First patients receive experimental lymphoma drug in groundbreaking immune therapy trial

NCT ID NCT05737628

Summary

This is the first study in people testing a new immune-boosting drug called BYON4228, both alone and combined with an existing lymphoma drug (rituximab). It aims to find safe doses and see if it helps patients whose B-cell non-Hodgkin's lymphoma has returned or hasn't responded to at least two prior treatments. The research will measure side effects and whether the treatment shrinks tumors.

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Contacts and locations

Locations

  • ASST Spedali Civili di Brescia

    Brescia, Italy

  • Centro Integral Oncológico Clara Campal (CIOCC) Hospital Universitario HM Sanchinarro

    Madrid, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, Spain

  • IRCCS Ospedale San Raffaele

    Milan, Italy

  • Institut Català d'Oncologia

    Barcelona, Spain

  • Instituto Europeo di Oncologia

    Milan, Italy

  • Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRCCS IRST

    Ravenna, Italy

  • Istituto di Candiolo - Fondazione del Piemonte per l'Oncologia - IRCCS

    Candiolo, Italy

  • Radboud UMC

    Nijmegen, Netherlands

  • The Christie NHS Foundation Trust

    Manchester, United Kingdom

  • University Hospitals Plymouth NHS Trust

    Plymouth, United Kingdom

  • Vrije Universiteit Medisch Centrum

    Amsterdam, Netherlands

Conditions

Explore the condition pages connected to this study.