Major trial tests new drug combo against standard treatment for advanced lung cancer

NCT ID NCT05899608

Recruiting now Disease control Sponsor: Summit Therapeutics Source: ClinicalTrials.gov ↗

Summary

This study compares two different drug combinations for people with advanced non-small cell lung cancer that has spread. About 1600 participants will receive either a new drug called ivonescimab or the standard drug pembrolizumab, both combined with chemotherapy. The main goals are to see which combination helps people live longer and keeps the cancer from growing.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

"George Papanikolaou" General Hospital of Thessaloniki
RECRUITING

Thessaloniki, 57010, Greece
Acibadem Bel Medic General Hospital
RECRUITING

Belgrade, 11000, Serbia
Actualidad Basada en Investigación del Cáncer
RECRUITING

Guadalajara, 44680, Mexico
Althian Clinical Research
RECRUITING

Monterrey, 64060, Mexico
American Oncology Partners, PA
RECRUITING

Kansas City, Missouri, 64132, United States
Arke SMO S.A DE C.V
RECRUITING

Mexico City, 06700, Mexico
Ascension Sacred Heart Health System
RECRUITING

Pensacola, Florida, 32504, United States
Ascension Saint Agnes Hospital
RECRUITING

Baltimore, Maryland, 21229, United States
Asklepios Klinik Gauting GmbH
RECRUITING

Gauting, 82131, Germany
Azienda Ospedaliera "Istituti Ospitalieri" di Cremona
RECRUITING

Cremona, 26100, Italy
Azienda Ospedaliera Universitaria Senese - Istituto Toscano Tumori
RECRUITING

Siena, 53100, Italy
Azienda Ospedaliero Universitaria delle Marche
RECRUITING

Ancona, 60126, Italy
Azienda Sanitaria Territoriale Pesaro Urbino (AST PU)
RECRUITING

Pesaro, 61122, Italy
BRCR Medical Center Inc
RECRUITING

Plantation, Florida, 33322, United States
BRCR Medical Center Inc.
RECRUITING

Tamarac, Florida, 33321, United States
Banner MD Anderson Cancer Center at North Colorado Medical Center
RECRUITING

Loveland, Colorado, 80538, United States
Banner University Medical Center
RECRUITING

Phoenix, Arizona, 85006, United States
Baptist Health
RECRUITING

Lexington, Kentucky, 40503, United States
Beaumont Hospital
RECRUITING

Dublin, D09V2N0, Ireland
Beijing Chest Hospital
RECRUITING

Tongzhou, Beijing Municipality, 101125, China
BioResearch Partner- Hialeah Hospital
RECRUITING

Hialeah, Florida, 33013, United States
CHU UC Louvain Namur
RECRUITING

Louvain-la-Neuve, 6800, Belgium
CRI Centro Regiomontano de Investigación S.C.
RECRUITING

Monterrey, 64060, Mexico
Cancer Care NW Centers
RECRUITING

Spokane, Washington, 99202, United States
Cancer Care of Brevard
RECRUITING

Palm Bay, Florida, 32901, United States
Cancer Hospital Affiliated to Xinjiang Medical University
RECRUITING

Ürümqi, Xinjiang, 830011, China
Cancer Hospital Chinese Academy of Medical Science
RECRUITING

Beijing, 100021, China
Cancer Specialists of North Florida
RECRUITING

Jacksonville, Florida, 32256, United States
Carbone Cancer Center
RECRUITING

Madison, Wisconsin, 53792, United States
Cedar Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Centre Hospitalier (Intercommunal) De Cornouaille Quimper
RECRUITING

Quimper, 29107, France
Centre Hospitalier Intercommunal de Creteil (CHIC
RECRUITING

Créteil, 94010, France
Centre Hospitalier Lyon-Sud
RECRUITING

Pierre-Bénite, 69495, France
Centre Hospitalier Regional Universitaire (CHRU) Brest
RECRUITING

Brest, 29200, France
Centre Hospitalier Regional et Universitaire de Tours
RECRUITING

Tours, 37044, France
Centre Hospitalier Universitaire (CHU) de Caen
RECRUITING

Caen, 14033, France
Centre Hospitalier Universitaire (CHU) de Rennes
RECRUITING

Rennes, 35033, France
Centre Hospitalier Universitaire de Montpellier (CHU Montpellier)
RECRUITING

Montpellier, 34295, France
Centre de Cancérologie de la Sarthe
RECRUITING

Le Mans, 72000, France
Centro de Atención Oncológica Viva
RECRUITING

La Paz, 23040, Mexico
Centro de Atención Oncológica Viva
RECRUITING

Mexico City, 06760, Mexico
Centro de Investigación Clínica GRAMEL
RECRUITING

Mexico City, 03720, Mexico
Centro di Riferimento Oncologico di Aviano
RECRUITING

Aviano, 33081, Italy
Centrum Onkologii im. prof. F. Lukaszczyka w Bydgoszczy
RECRUITING

Bydgoszcz, 85796, Poland
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Clinica Universidad de Navarra (CUN) - Pamplona
RECRUITING

Pamplona, 31008, Spain
Dicle University
RECRUITING

Diyarbakır, 21280, Turkey (Türkiye)
Exigent Network
RECRUITING

Petersburg, Florida, 33709, United States
First Affiliated Hospital of Gannan Medical University
RECRUITING

Ganzhou, Jiangxi, 341000, China
Florida Cancer Specialists & Research Institute (FCS) - North
RECRUITING

St. Petersburg, Florida, 33705, United States
Florida Cancer Specialists & Research Institute (FCS)-East
RECRUITING

Fort Myers, Florida, 33901, United States
Florida Cancer Specialists & Research Institute (FCS)-South
RECRUITING

West Palm Beach, Florida, 33401, United States
Fondazione IRCCS - Istituto Nazionale dei Tumori - Milano
RECRUITING

Milan, 20133, Italy
Fondazione IRCCS Policlinico San Matteo
RECRUITING

Pavia, 27100, Italy
Fondazione IRCCS San Gerardo dei Tintori
RECRUITING

Monza, 20900, Italy
Fu Yang People's Hospital
RECRUITING

Yangzhou, Anhui, 236010, China
Fudan University Shanghai Cancer Center
RECRUITING

Xuhui, Shanghai Municipality, 200032, China
Fujian Cancer Hospital
RECRUITING

Fuzhou, Fujian, 350014, China
Fujian Cancer Hospital
RECRUITING

Guangzhou, Guangdong, 510230, China
Fujita Health University Hospital
RECRUITING

Aichi, 470-1192, Japan
Galenos General Clinic
RECRUITING

Thessaloniki, 54622, Greece
Galway Univeristy Hospitals
RECRUITING

Galway, H91 YR71, Ireland
Gansu Provincial Cancer Hospital
RECRUITING

Lanzhou, Gansu, 730013, China
General Hospital of Athens
RECRUITING

Athens, 11527, Greece
General Hospital of Athens Alexandra
RECRUITING

Athens, 11528, Greece
Guangxi Medical University Cancer Hospital
RECRUITING

Guangxi, 530021, China
Gustave Roussy Oncologie Médical
RECRUITING

Villejuif, 94800, France
H Universitario Virgen Del Rocio
RECRUITING

Seville, 41013, Spain
Hainan General Hospital
RECRUITING

Haikou, Hainan, 190000, China
Hakodate Goryoukaku Hospital
RECRUITING

Hokkaido, 040-8611, Japan
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150081, China
Hartford Hospital
RECRUITING

Hartford, Connecticut, 06053, United States
Health Pharma Professional Research S.A. de C.V.
RECRUITING

Mexico City, 03100, Mexico
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450003, China
Henan University of Science and Technology Affiliated Anyang Cancer Hospital
RECRUITING

Anyang, Henan, 471023, China
Henan University of Science and Technology Affiliated Anyang Cancer Hospital
RECRUITING

Zhengzhou, Henan, 455000, China
Henry Dunant Hospital Center
RECRUITING

Athens, 11526, Greece
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Hirosaki University Hospital
RECRUITING

Hirosaki, 036-8563, Japan
Hiroshima University Hospital
RECRUITING

Hiroshima, 734-8551, Japan
Hopital Nord
RECRUITING

Marseille, 13915, France
Hospital Alvaro Cunqueiro (HAC)
RECRUITING

Vigo, 36312, Spain
Hospital Clinico Universitario de Valencia (CHUV)
RECRUITING

Valencia, 46010, Spain
Hospital La Fe Bulevar Sur
RECRUITING

Valencia, 46206, Spain
Hospital Regional Universitario de Málaga
RECRUITING

Málaga, 29011, Spain
Hospital Universitari Dexeus
RECRUITING

Barcelona, 08028, Spain
Hospital Universitari Germans Trias i Pujol
RECRUITING

Badalona, 08916, Spain
Hospital Universitario "Dr. José Eleuterio González"
RECRUITING

Monterrey, 64460, Mexico
Hospital Universitario La Paz
RECRUITING

Madrid, 28046, Spain
Hospital Universitario Lucus Augusti (HULA)
RECRUITING

Lugo, 27003, Spain
Hospital Universitario de Badajoz
RECRUITING

Badajoz, 06080, Spain
Hospital Universitario de Jaén
RECRUITING

Jaén, 23007, Spain
Hospital de la Santa Creu i de Sant Pau
RECRUITING

Barcelona, 08025, Spain
Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States
Hunan Cancer Hospital Thoracic Medicine 1
RECRUITING

Changsha, Hunan, 410013, China
Hunan Cancer Hospital Thoracic Medicine 2
RECRUITING

Changsha, 410013, China
I Can Oncology Center
RECRUITING

Monterrey, 64710, Mexico
Illinois Cancer Care
RECRUITING

Peoria, Illinois, 61615, United States
Institut Curie
RECRUITING

Paris, 75000, France
Institut Za Plucne Bolesti Vojvodine Klinika za pulmolosku onkologiju
RECRUITING

Kamenica, 21204, Serbia
Institut d'Investigacio Biomedica de Girona Dr. Josep Trueta
RECRUITING

Girona, 17007, Spain
Institut de Cancérologie de l'Ouest
RECRUITING

Saint-Herblain, 44805, France
Institut de cancérologie Strasbourg Europe (ICANS)
RECRUITING

Strasbourg, 67033, France
Instituto Oncologico Baselga (IOB)
RECRUITING

Barcelona, 08003, Spain
Instytut Msf Sp. z o.o.
RECRUITING

Lodz, 90-302, Poland
Interbalkan Medical Center of Thessaloniki
RECRUITING

Athens, 57010, Greece
Istinye University Bahceshir Liv Hospital
RECRUITING

Istanbul, 34460, Turkey (Türkiye)
Istituti Fisioterapici Ospitalieri (IFO)
RECRUITING

Roma, 00144, Italy
Istituto Europeo di Oncologia (IEO)
RECRUITING

Genova, 16149, Italy
Istituto Europeo di Oncologia (IEO)
RECRUITING

Milan, 20133, Italy
Jiangxi Cancer Hospital
RECRUITING

Nanchang, Jiangxi, 330209, China
Jinhua Municipal Central Hospital
RECRUITING

Jinhua, Zhejiang, 321000, China
Kaiser Permanente
RECRUITING

Vallejo, California, 94589, United States
Kanagawa Cancer Center
RECRUITING

Yokohama, 241-8515, Japan
Kansai Medical University Hospital
RECRUITING

Osaka, 573-1191, Japan
Karmanos Cancer Insitute
RECRUITING

Detroit, Michigan, 48201, United States
Karolinska University Hospital
RECRUITING

Stockholm, 141 86, Sweden
Klinicki Centar Srbije
RECRUITING

Belgrade, 11000, Serbia
Klinicko Bolnicki Centar (KBC) Bezanijska Kosa
RECRUITING

Belgrade, 11080, Serbia
Klinikum Esslingen GmbH
RECRUITING

Esslingen am Neckar, 73730, Germany
Klinikverbund Allgaeu - Klinikum Kempte
RECRUITING

Kempten, 87435, Germany
Kocaeli University Hospital
RECRUITING

İzmit, 34460, Turkey (Türkiye)
Krankenhaus Nordwest GmbH
RECRUITING

Frankfurt, 60488, Germany
LA Cancer Network
RECRUITING

Anaheim, California, 92801, United States
Lahey Hospital
RECRUITING

Burlington, Massachusetts, 01805, United States
Leeds Teaching Hospitals NHS
RECRUITING

Leeds, LS2 9JT, United Kingdom
Levine Center
RECRUITING

Charlotte, North Carolina, 28204, United States
Linyi People's Hospital
RECRUITING

Linyi, Shandong, 276001, China
London Regional (LRCP)
RECRUITING

London, Ontario, N6A5W9, Canada
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mayo Clinic
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Med Polonia Sp. z o.o. NSZOZ
RECRUITING

Poznan, 60-693, Poland
Medical University of South Carolina (MUSC)
RECRUITING

Charleston, South Carolina, 29425, United States
Memorial Ankara Hospital
RECRUITING

Ankara, 06520, Turkey (Türkiye)
Memorial Cancer Institute
RECRUITING

Pembroke Pines, Florida, 33028, United States
Memorial Saglik Grubu Bahçelievler Hospital
RECRUITING

Istanbul, 34180, Turkey (Türkiye)
Memorial Sloan Kettering
RECRUITING

New York, New York, 10065, United States
Metropolitan General Hospital
RECRUITING

Athens, 15562, Greece
Mi Tres Torres
RECRUITING

Barcelona, 08107, Spain
Mianyang Central Hospital
RECRUITING

Mianyang, Sichuan, 621099, China
Mount Sinai
RECRUITING

New York, New York, 10029, United States
München Klinik gGmbH
RECRUITING

Munich, 81975, Germany
Nanyang Central Hospital
RECRUITING

Nanyang, Henan, 473001, China
Nara Medical University Hospital
RECRUITING

Kashihara, 634-8522, Japan
National Cancer Center Hospital (NCCH)
RECRUITING

Tokyo, 104-0045, Japan
National Hospital Organization - Hokkaido Cancer Center
RECRUITING

Hokkaido, 003-0804, Japan
National Hospital Organization Kyusyu Medical Center
RECRUITING

Fukuoka, 810-8563, Japan
National Hospital Organization Yamaguchi Ube Medical Center
RECRUITING

Yamaguchi, 755-0241, Japan
Necmettin Erbakan University Meram Medical Faculty Hospital
RECRUITING

Konya, 42080, Turkey (Türkiye)
Ningbo Medical Center Lihuili Hospital
RECRUITING

Ningbo, Zhejiang, 315010, China
Ocala Oncology
RECRUITING

Ocala, Florida, 34474, United States
Okayama University Hospital
RECRUITING

Okayama, 700-8558, Japan
Olympion Hospital
RECRUITING

Pátrai, 26443, Greece
Oncology Hematology Care (OHC), Inc
RECRUITING

Cincinnati, Ohio, 45242, United States
Osaka Medical and Pharmaceutical University Hospital (OMPU Hp)
RECRUITING

Osaka, 569-8686, Japan
Ospedale G.B. Rossi Borgo Roma
RECRUITING

Verona, 37134, Italy
Ospedale P. Pederzoli
RECRUITING

Peschiera del Garda, 37019, Italy
Ospedale San Luca
RECRUITING

Lucca, 55100, Italy
Ottawa Cancer Center
RECRUITING

Ottawa, Ontario, K1H8L6, Canada
Panamerican Clinical Research S.A de C.V.
RECRUITING

Guadalajara, 44670, Mexico
Park Nicollet Institute
RECRUITING

Saint Paul, Minnesota, 55101, United States
Peking University People's Hospital
RECRUITING

Beijing, 100044, China
Prisma Health-Upstate
RECRUITING

Greenville, South Carolina, 29605, United States
Providence Medical Foundation
RECRUITING

Santa Rosa, California, 95403, United States
Qingdao Central Hospital
RECRUITING

Qingdao, Shandong, 266042, China
Region Gävleborg Gävle Sjukhus Gävle Sjukhus
RECRUITING

Uppsala, 803 24, Sweden
Renati Innovation S.A.P.I. DE C.V.
RECRUITING

Guadalajara, 44680, Mexico
Rocky Mountain Cancer
RECRUITING

Lone Tree, Colorado, 80124, United States
SCRI-Nashville
RECRUITING

Nashville, Tennessee, 37203, United States
Saskatchewan Cancer
RECRUITING

Regina, Saskatchewan, S4T7T1, Canada
Sendai Kousei Hospital
RECRUITING

Miyagi, 981-0914, Japan
Shandong Cancer Hospital
RECRUITING

Jinan, Shandong, 250117, China
Shanghai Chest Hospital
RECRUITING

Xuhui, Shanghai Municipality, 200940, China
Shanghai Pulmonary Hospital
RECRUITING

Yangpu, Shanghai Municipality, 200433, China
Shanxi Provincial Cancer Hospital
RECRUITING

Taiyuan, Shanxi, 030013, China
Shengjing Hospital Of China Medical University
RECRUITING

Shenyang, Liaoning, 110004, China
Shinshu University Hospital
RECRUITING

Matsumoto, 390-8621, Japan
Shizuoka Cancer Center (SCC)
RECRUITING

Shizuoka, 411-8777, Japan
Sidney Kimmel Comprehensive Cancer Center
RECRUITING

Baltimore, Maryland, 21187, United States
St. Bartholomew's hospital
RECRUITING

London, EC1A 7BE, United Kingdom
St. James's Hospital (SJH)
RECRUITING

Dublin, D08 NHY1, Ireland
St. Vincent Cancer Center
RECRUITING

Billings, Montana, 59102, United States
Sutter Institute for Medical Research
RECRUITING

Sacramento, California, 95816, United States
Swedish Cancer Institute
RECRUITING

Seattle, Washington, 98103, United States
Szpital Specjalistyczny w Prabutach
RECRUITING

Prabuty, 82-550, Poland
TMC Healthcare
RECRUITING

Tucson, Arizona, 85711, United States
TaiZhou Hospital Of Zhejiang Province
RECRUITING

Taizhou, Zhejiang, 31700, China
Texas Oncology- Austin
RECRUITING

Austin, Texas, 78745, United States
Texas Oncology-Dallas
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology-San Antonio
RECRUITING

San Antonio, Texas, 78216, United States
Texas Oncology-Tyler
RECRUITING

Tyler, Texas, 75702, United States
The Affiliated Hospital of Xuzhou Medical University
RECRUITING

Xuzhou, Jiangsu, 2210000, China
The Cancer institute Hospital
RECRUITING

Tokyo, 135-8550, Japan
The Christie NHS Foundation Trust
RECRUITING

Manchester, M20 4BX, United Kingdom
The Fifth Medical Center of the General Hospital of the Chinese People's Liberation Army
RECRUITING

Beijing, 100853, China
The First Affiliated Hospital Of University Of South China
RECRUITING

Hengyang, Hunan, 421001, China
The First Affiliated Hospital of Guangxi Medical University
RECRUITING

Nanning, Guangxi, 530000, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330006, China
The First Affiliated Hospital of Yangtze University
RECRUITING

Jingzhou, Hubei, 434023, China
The First Affiliated Hospital,Zhejiang University
RECRUITING

Hanzhou, Zhejiang, 310003, China
The Fourth Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 050011, China
The Oncology Institute of Hope & Innovation
RECRUITING

Cerritos, California, 90703, United States
The Second Affiliated Hospital of AFMU
RECRUITING

Xi'an, Shaanxi, 710004, China
The first affiliated Hospital of xi'an jiao tong university
RECRUITING

Xi'an, Shaanxi, 710049, China
Tottori University Hospital
RECRUITING

Yonago, 683-8504, Japan
Trinity Health
RECRUITING

Ann Arbor, Michigan, 48197, United States
UC Davis Medical Center
RECRUITING

Sacramento, California, 95817, United States
UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
Unicancer - Centre François Baclesse (CFB)
RECRUITING

Caen, 14059, France
Universidad Autonoma de Madrid (UAM)
RECRUITING

Madrid, 28040, Spain
Universidad de Las Palmas de Gran Canaria
RECRUITING

Las Palmas de Gran Canaria, 35016, Spain
Universita degli Studi della Campania "Luigi Vanvitelli"
RECRUITING

Naples, 80131, Italy
Universitaetsklinikum Giessen und Marburg
RECRUITING

Giesen, 35392, Germany
Universitaetsklinikum Heidelberg (UKHD)
RECRUITING

Heidelberg, 69126, Germany
Universitaetsklinikum Jena
RECRUITING

Jena, 07747, Germany
University Clinical Center Niš
RECRUITING

Niš, 18000, Serbia
University General Hospital of Patras
RECRUITING

Pátrai, 26504, Greece
University Hospitals Case Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of Arkansas
RECRUITING

Little Rock, Arkansas, 72205, United States
University of California Los Angeles (UCLA)
RECRUITING

Santa Monica, California, 90404, United States
University of Kansas Cancer Center
RECRUITING

Westwood, Kansas, 66205, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Nebraska Medical Center (UNMC)
RECRUITING

Omaha, Nebraska, 68105, United States
University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27514, United States
University of Southern California (USC)
RECRUITING

Los Angeles, California, 90033, United States
University of Texas at Tyler
RECRUITING

Tyler, Texas, 75708, United States
Universitätsklinikum Schleswig-Holstein
RECRUITING

Lübeck, 23538, Germany
Univerzitetski Klinicki Centar Kragujevac
RECRUITING

Kragujevac, 34000, Serbia
Valkyrie Clinical Trials
RECRUITING

Los Angeles, California, 90067, United States
Vall d'Hebron University
RECRUITING

Barcelona, 08035, Spain
Virginia Cancer
RECRUITING

Reston, Virginia, 20190, United States
Virginia Oncology Associates
RECRUITING

Norfolk, Virginia, 23502, United States
Vojnomedicinska Akademija (VMA)
RECRUITING

Belgrade, 11040, Serbia
Washington University St.Louis
RECRUITING

St Louis, Missouri, 63110, United States
West Cancer Center
RECRUITING

Memphis, Tennessee, 38138, United States
Willamette Valley Cancer Institute and Research Center (WVCI)
RECRUITING

Eugene, Oregon, 97401, United States
Wojskowy Instytut Medczny
RECRUITING

Warsaw, 04-141, Poland
Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, 410000, China
Xiangyang Central Hospital
RECRUITING

Xiangyang, Hubei, 441100, China
Yale University
RECRUITING

New Haven, Connecticut, 06510, United States
Yunnan Cancer Hospital
RECRUITING

Kunming, Yunnan, 650118, China
Zhejiang Cancer Hospital
RECRUITING

Hanzhou, Zhejiang, 310022, China
az Glorieux
RECRUITING

Ronse, 9600, Belgium

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CANCER