New pill aims to outperform chemo for tough lung cancer

NCT ID NCT06151574

Recruiting now Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

Summary

This study is testing if a new oral medicine called zongertinib works better than the current standard IV treatment for adults with advanced lung cancer that has a specific genetic change (HER2 mutation). Participants, who have not yet received treatment for their advanced cancer, are randomly assigned to receive either the daily pill or the standard combination of IV drugs. The main goal is to see which treatment better slows the cancer's growth and improves survival and quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LUNG CANCER, NON-SQUAMOUS, NON-SMALL CELL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

A. O. Ospedale Circolo Fond. Macchi
NOT_YET_RECRUITING

Varese, 21100, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
AOU Policlinico G. Rodolico San Marco
RECRUITING

Catania, 95123, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
AOU Policlinico Umberto I
NOT_YET_RECRUITING

Roma, 00161, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Aichi Cancer Center Hospital
RECRUITING

Aichi, Nagoya, 464-8681, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Asan Medical Center
ACTIVE_NOT_RECRUITING

Seoul, 05505, South Korea
Associacao Dr. Bartholomeu Tacchini
ACTIVE_NOT_RECRUITING

Bento Gonçalves, 95700-084, Brazil
Austin Health
ACTIVE_NOT_RECRUITING

Heidelberg, Victoria, 3084, Australia
Azienda Ospedaliera Unversitaria di Parma
RECRUITING

Parma, 43100, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Beijing Cancer Hospital
RECRUITING

Beijing, 100142, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Bradford Hill- Centro de Investigación Clínica
COMPLETED

Recoleta, 8420383, Chile
Brussels - HOSP Jules Bordet
ACTIVE_NOT_RECRUITING

Anderlecht, 1070, Belgium
CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia
ACTIVE_NOT_RECRUITING

Santo André, 09060-650, Brazil
CTR Leon Berard
RECRUITING

Lyon, 69373, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cancer Care Specialists
ACTIVE_NOT_RECRUITING

Reno, Nevada, 89511, United States
Cancer Hospital of Chinese Academy of Medical Science
NOT_YET_RECRUITING

Beijing, 1000021, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Carolina Blood and Cancer Care Associates, PA
COMPLETED

Rock Hill, South Carolina, 29732, United States
Centro Hospitalar Lisboa Norte Hospital Pulido Valente
COMPLETED

Lisbon, 1769-001, Portugal
Centro Oncologico Riojano Integral (CORI)
COMPLETED

La Rioja, F5300COE, Argentina
Chang Gung Memorial Hospital, Linkou
RECRUITING

Taoyuan District, 330, Taiwan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Chung Shan Medical University Hospital
RECRUITING

Taichung, 404, Taiwan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Chungbuk National University Hospital
ACTIVE_NOT_RECRUITING

Cheongiu, 28644, South Korea
Clearview Cancer Institute
COMPLETED

Huntsville, Alabama, 35805, United States
ClinRé 001-022 (Premier Cancer Care and Infusion Center)
ACTIVE_NOT_RECRUITING

Fresno, California, 93710, United States
Clinic Floridsdorf
ACTIVE_NOT_RECRUITING

Vienna, 1210, Austria
Clinica Adventista Belgrano
ACTIVE_NOT_RECRUITING

CABA, 1430, Argentina
Complejo Hospitalario Universitario A Coruña
NOT_YET_RECRUITING

A Coruña, 15006, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
FAICIC S de RL de C.V.
COMPLETED

Veracruz, 91900, Mexico
First Affiliated Hospital of Xiamen University
NOT_YET_RECRUITING

Xiamen, 361003, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 200032, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fujian Cancer Hospital
RECRUITING

Fuzhou, 350014, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fundação Faculdade Regional de Medicina de São José do Rio Preto
RECRUITING

São José do Rio Preto, 15090-000, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
Gabrail Cancer Center
COMPLETED

Canton, Ohio, 44718, United States
Gachon University Gil Medical Center
NOT_YET_RECRUITING

Incheon, 21565, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
Gemeinschaftskrankenhaus Havelhöhe gGmbH
RECRUITING

Berlin, 14089, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Greater Poland Center of Pulmonology and Thoracic Surgery
RECRUITING

Poznan, 60-569, Poland

Contact Phone: •••-•••-•••• Email: •••••@•••••
Guangdong Provincial People's Hospital
RECRUITING

Guangzhou, 510080, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Guy's Hospital
ACTIVE_NOT_RECRUITING

London, SE1 9RT, United Kingdom
HOP Civil
RECRUITING

Strasbourg, 67091, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
HOP Louis Pradel
NOT_YET_RECRUITING

Bron, 69677, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
HOP Nord
RECRUITING

Marseille, 13015, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
HOP Pontchaillou
RECRUITING

Rennes, 35000, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
HOP Tenon
RECRUITING

Paris, 75020, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hakodate Goryoukaku Hospital
RECRUITING

Hokkaido, Hakodate, 040-8611, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, 150081, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Health Pharma Professional Research S.A. de C.V.
RECRUITING

Mexico City, 03100, Mexico

Contact Phone: •••-•••-•••• Email: •••••@•••••
Henan Cancer Hospital
RECRUITING

Zhengzhou, 450008, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hirosaki University Hospital
RECRUITING

Aomori, Hirosaki, 036-8563, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hokkaido Cancer Center
RECRUITING

Hokkaido, Sapporo, 003-0804, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital CUF Porto
ACTIVE_NOT_RECRUITING

Porto, 4100-180, Portugal
Hospital CUF Tejo
COMPLETED

Lisbon, 1350-352, Portugal
Hospital Clinico Universitario de Valencia
ACTIVE_NOT_RECRUITING

Valencia, 46010, Spain
Hospital Duran i Reynals
ACTIVE_NOT_RECRUITING

Barcelona, 08908, Spain
Hospital General Universitario Gregorio Marañón
COMPLETED

Madrid, 28009, Spain
Hospital General Universitario de Alicante
COMPLETED

Alicante, 03010, Spain
Hospital Regional Universitario de Málaga
ACTIVE_NOT_RECRUITING

Málaga, 29010, Spain
Hospital Santa Creu i Sant Pau
ACTIVE_NOT_RECRUITING

Barcelona, 08026, Spain
Hospital Sao Lucas da PUCRS
RECRUITING

Porto Alegre, 90610-000, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitari Vall D Hebron
ACTIVE_NOT_RECRUITING

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre
ACTIVE_NOT_RECRUITING

Madrid, 28041, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, 28046, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario Ramon Y Cajal
ACTIVE_NOT_RECRUITING

Madrid, 28034, Spain
Hospital Virgen del Rocío
ACTIVE_NOT_RECRUITING

Seville, 41013, Spain
Hospital de Basurto
ACTIVE_NOT_RECRUITING

Bilbao, 48013, Spain
Hospital do Cancer de Londrina
COMPLETED

Londrina, 86015-520, Brazil
Huntsman Cancer Institute
ACTIVE_NOT_RECRUITING

Salt Lake City, Utah, 84112, United States
Hôpital Larrey - CHU de Toulouse
RECRUITING

Toulouse, 31059, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
ICESP - Instituto do Cancer do Estado de Sao Paulo
ACTIVE_NOT_RECRUITING

São Paulo, 01246-000, Brazil
INS Curie
RECRUITING

Paris, 75248, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Institut Gustave Roussy
RECRUITING

Villejuif, 94805, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Instituto Medico Especializado Alexander Fleming
ACTIVE_NOT_RECRUITING

Ciudad Autónoma de Bs As, C1426ANZ, Argentina
Instituto Médico de la Fundación Estudios Clínicos
ACTIVE_NOT_RECRUITING

Rosario, S2000DEJ, Argentina
Instituto Nacional de Cancerologia
ACTIVE_NOT_RECRUITING

México, 14080, Mexico
Instituto Oncologico de Cordoba
ACTIVE_NOT_RECRUITING

Córdoba, X5000, Argentina
Istituto Di Candiolo
RECRUITING

Candiolo (TO), 10060, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Nazionale IRCCS Tumori Fondazione Pascale
RECRUITING

Napoli, 80131, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Tumori Giovanni Paolo II
RECRUITING

Bari, 70124, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Japanese Foundation for Cancer Research
RECRUITING

Tokyo, Koto-ku, 135-8550, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Juntendo University Hospital
RECRUITING

Tokyo, Bunkyo-ku, 113-8431, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Justus-Liebig Universität Gießen
NOT_YET_RECRUITING

Giessen, 35392, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Kanagawa Cancer Center
RECRUITING

Kanagawa, Yokohama, 241-8515, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Kanazawa University Hospital
RECRUITING

Ishikawa, Kanazawa, 920-8641, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Kangbuk Samsung Hospital
ACTIVE_NOT_RECRUITING

Seoul, 03181, South Korea
Kaohsiung Chang Gung Memorial Hospital
RECRUITING

Kaohsiung City, 83301, Taiwan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Karolinska Universitetssjukhuset Solna
ACTIVE_NOT_RECRUITING

Stockholm, 171 76, Sweden
Komagome Hospital
RECRUITING

Tokyo, Bunkyo-ku, 113-8677, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Krems University Hospital
ACTIVE_NOT_RECRUITING

Krems, 3500, Austria
Kyushu University Hospital
RECRUITING

Fukuoka, Fukuoka, 812-8582, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Leicester Royal Infirmary
RECRUITING

Leicester, LE1 5WW, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
MED POLONIA SP Z O O, Clinical Trials Department,Poznan
ACTIVE_NOT_RECRUITING

Poznan, 60693, Poland
Maastricht University Medisch Centrum
ACTIVE_NOT_RECRUITING

Maastricht, 6229 HX, Netherlands
Meir Medical Center
RECRUITING

Kfar Saba, 4428164, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10461, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
National Cancer Center
ACTIVE_NOT_RECRUITING

Goyang, 10408, South Korea
National Cancer Center Hospital
RECRUITING

Tokyo, Chuo-ku, 104-0045, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
National Cancer Center Hospital East
COMPLETED

Chiba, Kashiwa, 277-8577, Japan
National Cancer Centre Singapore
ACTIVE_NOT_RECRUITING

Singapore, 168583, Singapore
National Taiwan University Cancer Center
RECRUITING

Taipei, 106, Taiwan

Contact Phone: •••-•••-•••• Email: •••••@•••••
National Taiwan University Hospital
RECRUITING

Taipei, 100, Taiwan

Contact Phone: •••-•••-•••• Email: •••••@•••••
National University Hospital-Singapore-22806
ACTIVE_NOT_RECRUITING

Singapore, 119228, Singapore
Nederlands Kanker Instituut - Antoni van Leeuwenhoek Amsterdam (METC AVL)
ACTIVE_NOT_RECRUITING

Amsterdam, 1066 CX, Netherlands
Northwell Health
COMPLETED

Lake Success, New York, 11042, United States
OPN Healthcare, Inc.
COMPLETED

Glendale, California, 91203, United States
Okayama University Hospital
RECRUITING

Okayama, Okayama, 700-8558, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
OncoClinicas Rio de Janeiro
RECRUITING

Rio de Janeiro, 22250-040, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
Oncology Center-Maria Sklodowska-Curie Institute
NOT_YET_RECRUITING

Warsaw, 02-781, Poland

Contact Phone: •••-•••-•••• Email: •••••@•••••
Oncology Hematology Associates
COMPLETED

Springfield, Missouri, 65807, United States
Osaka International Cancer Institute
RECRUITING

Osaka, Osaka, 541-8567, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Oslo Universitetssykehus HF, Radiumhospitalet
COMPLETED

Oslo, 0379, Norway
Pan American Center for Oncology Trials, LLC
COMPLETED

Rio Piedras, 00935, Puerto Rico
Pioneer Research Center - Bullhead City
COMPLETED

Bullhead City, Arizona, 86442, United States
Pius-Hospital, Oldenburg
RECRUITING

Oldenburg, 26121, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Polish Mother's Memorial Hospital - Research Institute
NOT_YET_RECRUITING

Lodz, 93-338, Poland

Contact Phone: •••-•••-•••• Email: •••••@•••••
Precision NextGen Oncology
COMPLETED

Beverly Hills, California, 90212, United States
Prince of Wales Hospital-Randwick-66496
ACTIVE_NOT_RECRUITING

Randwick, New South Wales, 2031, Australia
Princess Alexandra Hospital
ACTIVE_NOT_RECRUITING

Woolloongabba, Queensland, 4102, Australia
Princess Margaret Hospital
RECRUITING

Hong Kong, 999077, Hong Kong

Contact Phone: •••-•••-•••• Email: •••••@•••••
Queen Elizabeth Hospital-Hong Kong-51727
RECRUITING

Hong Kong, 51727, Hong Kong

Contact Phone: •••-•••-•••• Email: •••••@•••••
Queen Mary Hospital
RECRUITING

Hong Kong, 999077, Hong Kong

Contact Phone: •••-•••-•••• Email: •••••@•••••
Rabin Medical Center Beilinson
ACTIVE_NOT_RECRUITING

Petah Tikva, 49100, Israel
Rambam Medical Center
ACTIVE_NOT_RECRUITING

Haifa, 3109601, Israel
Regional Medical Oncology Center
COMPLETED

Wilson, North Carolina, 27893, United States
Royal North Shore Hospital-St Leonards-20807
ACTIVE_NOT_RECRUITING

St Leonards, New South Wales, 2065, Australia
SCRI Oncology Partners
ACTIVE_NOT_RECRUITING

Nashville, Tennessee, 37203, United States
Sahlgrenska Universitetsjukhuset
COMPLETED

Gothenburg, 413 45, Sweden
Samsung Medical Center
ACTIVE_NOT_RECRUITING

Seoul, 06351, South Korea
Scripps Green Hospital
ACTIVE_NOT_RECRUITING

La Jolla, California, 92037, United States
Severance Hospital
ACTIVE_NOT_RECRUITING

Seoul, 03722, South Korea
Sharp Memorial Hospital
ACTIVE_NOT_RECRUITING

San Diego, California, 92123, United States
Shikoku Cancer Center
RECRUITING

Ehime, Matsuyama, 791-0280, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Shizuoka Cancer Center
RECRUITING

Shizuoka, Sunto-gun, 411-8777, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine
RECRUITING

Hangzhou, 310016, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Sourasky Medical Center
ACTIVE_NOT_RECRUITING

Tel Aviv, 6423906, Israel
St John of God Subiaco Hospital
ACTIVE_NOT_RECRUITING

Subiaco, Western Australia, 6008, Australia
St. Louis Cancer Care, LLP
COMPLETED

Bridgeton, Missouri, 63044, United States
St. Marianna University Hospital
RECRUITING

Kanagawa, Kawasaki, 216-8511, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Swedish Cancer Institute
COMPLETED

Edmonds, Washington, 98026, United States
Swedish Cancer Institute
COMPLETED

Issaquah, Washington, 98029, United States
Swedish Cancer Institute
ACTIVE_NOT_RECRUITING

Seattle, Washington, 98104, United States
Taizhou Hospital of Zhejiang Province
RECRUITING

Taizhou, 317099, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Catholic University of Korea, St.Vincent's Hospital
ACTIVE_NOT_RECRUITING

Suwon, 16247, South Korea
The First Affiliated Hospital of Wenzhou Medical University
RECRUITING

Wenzhou, 325000, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
The First Affiliated Hospital, Zhejiang University
RECRUITING

Hangzhou, 310003, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Royal Marsden Hospital, Chelsea
ACTIVE_NOT_RECRUITING

London, SW3 6JJ, United Kingdom
The Royal Marsden Hospital, Sutton
ACTIVE_NOT_RECRUITING

Sutton, SM2 5PT, United Kingdom
Thoraxklinik-Heidelberg gGmbH am Universitätsklinikum Heidelberg
RECRUITING

Heidelberg, 69126, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tohoku University Hospital
RECRUITING

Miyagi, Sendai, 980-8574, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
UZ Leuven
ACTIVE_NOT_RECRUITING

Leuven, 3000, Belgium
Universitair Ziekenhuis Gent
ACTIVE_NOT_RECRUITING

Ghent, 9000, Belgium
University Hospital Kyoto Prefectural University of Medicine
RECRUITING

Kyoto, Kyoto, 602-8566, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Augsburg
RECRUITING

Augsburg, 86156, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Carl Gustav Carus Dresden
RECRUITING

Dresden, 01307, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Köln (AöR)
RECRUITING

Cologne, 50937, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Tübingen
NOT_YET_RECRUITING

Tübingen, 72076, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Valkyrie Clinical Trials
ACTIVE_NOT_RECRUITING

Los Angeles, California, 90067, United States
Vestre Viken HF, Drammen Sykehus
COMPLETED

Drammen, N-3004, Norway
Virginia Cancer Specialists, PC
ACTIVE_NOT_RECRUITING

Fairfax, Virginia, 22031, United States
Wakayama Medical University Hospital
RECRUITING

Wakayama, Wakayama, 641-8510, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
West China Hospital, Sichuan University
RECRUITING

Chengdu, 610042, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Western General Hospital
ACTIVE_NOT_RECRUITING

Edinburgh, EH4 2XU, United Kingdom
Wuhan Union Hospital
RECRUITING

Wuhan, 430022, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, 310022, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Zhongshan Hospital Affiliated to Fudan University
RECRUITING

Shanghai, 200032, China

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

LUNG CANCER, NON-SQUAMOUS, NON-SMALL CELL