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New hope for lung cancer patients: experimental drug aims to outperform current standard

NCT ID NCT06765109

Recruiting now Disease control Sponsor: Nuvalent Inc. Source: ClinicalTrials.gov ↗

Summary

This study tests whether a new drug called NVL-655 works better than the current standard treatment (alectinib) for people with advanced ALK-positive lung cancer who haven't had treatment before. About 450 participants will be randomly assigned to receive either the new drug or the standard treatment. Researchers will measure how long patients live without their cancer getting worse, including whether the drug better controls cancer that has spread to the brain.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A.C.Camargo Cancer Center

    RECRUITING

    São Paulo, 01509-010, Brazil

    Contact

  • AUSL Della Romagna - Ospedale Santa Maria delle Croci

    RECRUITING

    Ravenna, 48121, Italy

    Contact

  • Aarhus Universitetshospital

    RECRUITING

    Aarhus, 8200, Denmark

    Contact

  • AdventHealth Cancer Institute

    RECRUITING

    Orlando, Florida, 32804, United States

    Contact

  • Aichi Cancer Center

    RECRUITING

    Chikusa, 464-8681, Japan

    Contact

  • Antwerp University Hospital

    RECRUITING

    Edegem, 2650, Belgium

    Contact

  • Athens Medical Center

    RECRUITING

    Marousi, 151 25, Greece

    Contact

  • Austin Health

    RECRUITING

    Heidelberg, Victoria, 3084, Australia

    Contact

  • Azienda Ospedaliero Universitaria Pisana

    RECRUITING

    Pisa, 56126, Italy

    Contact

  • Azienda Ospedaliero Universitaria delle Marche

    RECRUITING

    Ancona, 60126, Italy

    Contact

  • Bacs-Kiskun Varmegyei Oktatokorhaz

    RECRUITING

    Kecskemét, 6000, Hungary

    Contact

  • Barbara Ann Karmanos Cancer Institute

    WITHDRAWN

    Detroit, Michigan, 48201, United States

  • Beacon International Specialist Centre

    RECRUITING

    Petaling Jaya, Selangor, 46050, Malaysia

    Contact

  • Bioclinic Thessaloniki

    RECRUITING

    Thessaloniki, 546 22, Greece

    Contact

  • CUF Porto Hospital

    RECRUITING

    Porto, 4100-180, Portugal

    Contact

  • Cambridge University Hospitals NHS Trust, Addenbrooke's Hospital

    RECRUITING

    Cambridge, NG5 1PB, United Kingdom

    Contact

  • Center for Lung Cancer, National Cancer Center

    RECRUITING

    Goyang-si, 10408, South Korea

    Contact

  • Centre Francois Baclesse

    RECRUITING

    Caen, 14076, France

    Contact

  • Centre Hospitalier Universitaire (CHU) Nantes Hopital Nord Laennec

    RECRUITING

    Nantes, 44093, France

    Contact

  • Centre Hospitalier Universitaire (CHU) de Bordeaux

    RECRUITING

    Pessac, 33604, France

    Contact

  • Centre Hospitalier Universitaire d' Angers

    RECRUITING

    Angers, 49000, France

    Contact

  • Centre Hospitalier Universitaire de Toulouse - Hopital Larrey

    RECRUITING

    Toulouse, 31059, France

    Contact

  • Centre Leon Berard

    RECRUITING

    Lyon, 69373, France

    Contact

  • Centro de Investigaciones Clinicas UC CICUC

    RECRUITING

    Santiago, 8320000, Chile

    Contact

  • Chung Shan Medical University

    RECRUITING

    Taichung, 40201, Taiwan

    Contact

  • Chungbuk National University Hospital

    RECRUITING

    Cheongju-si, 28644, South Korea

    Contact

  • Cliniques Universitaires Saint-Luc

    RECRUITING

    Brussels, 1200, Belgium

    Contact

  • Complejo Hospitalario Universitario a Coruña

    RECRUITING

    A Coruña, 15006, Spain

    Contact

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

  • Debreceni Egyetem Klinikai Kozpont Nagyerdei Campus

    RECRUITING

    Debrecen, 4032, Hungary

    Contact

  • Duke Cancer Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    RECRUITING

    Milan, 20133, Italy

    Contact

  • Fundacao Champalimaud

    RECRUITING

    Lisbon, 1400-038, Portugal

    Contact

  • Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto Hospital de Base

    RECRUITING

    São José do Rio Preto, 15090, Brazil

    Contact

  • Fundacion Arturo Lopez Perez FALP

    RECRUITING

    Providencia, 7500000, Chile

    Contact

  • Fundação Pio XII

    RECRUITING

    Barretos, 14784, Brazil

    Contact

  • Gachon University Gil Medical Center

    RECRUITING

    Incheon, 21565, South Korea

    Contact

  • Guy's Cancer Centre NHS Foundation Trust

    RECRUITING

    London, SE1 9RT, United Kingdom

    Contact

  • H Lee Moffitt Cancer Center and Research Institute

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

  • HRH Princess Maha Chakri Sirindhorn Medical Center

    RECRUITING

    Ongkharak, 26120, Thailand

    Contact

  • Helios Klinikum Emil von Behring GmbH

    RECRUITING

    Berlin, 14165, Germany

    Contact

  • Henry Dunant Hospital Center

    RECRUITING

    Athens, 115 26, Greece

    Contact

  • Herlev and Gentofte Hospital

    RECRUITING

    Herlev, 02730, Denmark

    Contact

  • Hoag Hospital Newport Beach

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact

  • Hospital Amaral Carvalho

    RECRUITING

    São Paulo, 17210-080, Brazil

    Contact

  • Hospital General Universitario Gregorio Marañon

    RECRUITING

    Madrid, 28007, Spain

    Contact

  • Hospital Kuala Lumpur

    RECRUITING

    Kuala Lumpur, Kuala Lumpur, 50586, Malaysia

    Contact

  • Hospital Nord

    RECRUITING

    Marseille, 13015, France

    Contact

  • Hospital Pulau Pinang

    RECRUITING

    George Town, Pulau Pinang, 10450, Malaysia

    Contact

  • Hospital Regional Universitario de Malaga

    RECRUITING

    Málaga, 29010, Spain

    Contact

  • Hospital Sao Lucas Da Pontificia Universidade Catolica Do Rio Grande Do Sul

    RECRUITING

    Porto Alegre, 90610, Brazil

    Contact

  • Hospital Umum Sarawak

    RECRUITING

    Kuching, 93586, Malaysia

    Contact

  • Hospital Universitari de Girona Dr Josep Trueta

    RECRUITING

    Girona, 17007, Spain

    Contact

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

    Contact

  • Hospital Universitario Ramon y Cajal

    RECRUITING

    Madrid, 28034, Spain

    Contact

  • Hospital Universitario Virgen Macarena

    RECRUITING

    Seville, 41009, Spain

    Contact

  • Hospital Universitario Virgen del Rocio

    RECRUITING

    Seville, 41013, Spain

    Contact

  • Hospital de Cascais

    RECRUITING

    Alcabideche, 2755-009, Portugal

    Contact

  • ICO Badalona H.U. Germans Trias i Pujol

    RECRUITING

    Badalona, 08916, Spain

    Contact

  • IRCCS Istituto Tumori Giovanni Paolo II

    RECRUITING

    Bari, 70124, Italy

    Contact

  • Institut Bergonie

    RECRUITING

    Bordeaux, 33000, France

    Contact

  • Institut Kanser Negara

    RECRUITING

    Putrajaya, Putrajaya, 62250, Malaysia

    Contact

  • Institut Regional du Cancer de Montpellier

    RECRUITING

    Montpellier, 34298, France

    Contact

  • Instituto Portugues de Oncologia do Porto Francisco Gentil, E.P.E.

    RECRUITING

    Porto, 4200-072, Portugal

    Contact

  • Irmandade Da Santa Casa de Misericordia de Porto Alegre

    RECRUITING

    Porto Alegre, 90035, Brazil

    Contact

  • Istituti Fisioterapici Ospitalieri - IRCCS Istituto Nazionale Tumori Regina Elena

    RECRUITING

    Roma, 00144, Italy

    Contact

  • Istituto Clinico Humanitas

    RECRUITING

    Milan, 20089, Italy

    Contact

  • Istituto Europeo di Oncologia

    RECRUITING

    Milan, 20141, Italy

    Contact

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST)

    RECRUITING

    Meldola, 47014, Italy

    Contact

  • Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia

    RECRUITING

    Torino, 10060, Italy

    Contact

  • Kanagawa Cancer Center

    RECRUITING

    Yokohama, 241-8515, Japan

    Contact

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, 80756, Taiwan

    Contact

  • Kindai University Hospital

    RECRUITING

    Sakai, 590-0197, Japan

    Contact

  • Klinikum Esslingen GmbH

    RECRUITING

    Esslingen am Neckar, 73730, Germany

    Contact

  • Kyushu University Hospital

    RECRUITING

    Fukuoka, Fukuoka, 812-8582, Japan

    Contact

  • LungenClinic Grosshansdorf GmBH

    RECRUITING

    Großhansdorf, D-22927, Germany

    Contact

  • Lungenfachklinik Immenhausen

    RECRUITING

    Immenhausen, 34376, Germany

    Contact

  • MVZ Onkologie Velbert

    RECRUITING

    Velbert, 42551, Germany

    Contact

  • Maharaj Nakorn Chiang Mai Hospital

    RECRUITING

    Chiang Mai, 50200, Thailand

    Contact

  • Maidstone Hospital

    RECRUITING

    Maidstone, ME16 9QQ, United Kingdom

    Contact

  • Matrai Gyogyintezet

    RECRUITING

    Gyöngyös, 7151, Hungary

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • National Cancer Centre Singapore

    RECRUITING

    Singapore, 168583, Singapore

    Contact

  • National Cheng Kung University Hospital

    RECRUITING

    Tainan, 70403, Taiwan

    Contact

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

    Contact

  • Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis

    RECRUITING

    Amsterdam, 1066 CX, Netherlands

    Contact

  • Nemocnice AGEL Nový Jičín a.s.

    RECRUITING

    Nový Jičín, 74101, Czechia

    Contact

  • Nottingham City Hospital

    RECRUITING

    Nottingham, NG5 1PB, United Kingdom

    Contact

  • Okayama University Hospital

    RECRUITING

    Okayama, 700-8558, Japan

    Contact

  • Oncovida - Santiago

    RECRUITING

    Santiago, 8320000, Chile

    Contact

  • One Day Med

    RECRUITING

    Szczecin, 70-419, Poland

    Contact

  • Optum Medical Care, PC

    RECRUITING

    Westbury, New York, 11590, United States

    Contact

  • Osaka International Cancer Institute

    RECRUITING

    Osaka, 541-8567, Japan

    Contact

  • Palo Verde Hematology Oncology

    RECRUITING

    Glendale, Arizona, 85304, United States

    Contact

  • Peter MacCallum Cancer Centre

    RECRUITING

    Melbourne, 3000, Australia

    Contact

  • Phramongkutklao Hospital

    RECRUITING

    Bangkok, 10400, Thailand

    Contact

  • Prince of Wales Hospital

    RECRUITING

    Shatin, Hong Kong

    Contact

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 1L7, Canada

    Contact

  • Queen Elizabeth Hospital

    RECRUITING

    Hong Kong, Hong Kong

    Contact

  • Queen Mary Hospital Department of Medicine

    RECRUITING

    Hong Kong, 999077, Hong Kong

    Contact

  • Radboud University Medical Center

    RECRUITING

    Nijmegen, 6525 GA, Netherlands

    Contact

  • Rajavithi Hospital

    RECRUITING

    Din Daeng, 10400, Thailand

    Contact

  • Ramathibodi Hospital, Mahidol University

    RECRUITING

    Bangkok, 10400, Thailand

    Contact

  • Rocky Mountain Cancer Centers

    RECRUITING

    Boulder, Colorado, 80218, United States

    Contact

  • Royal Free London NHS Foundation Trust

    RECRUITING

    Hampstead, NW3 2QG, United Kingdom

    Contact

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

    Contact

  • Sanatorio Allende

    RECRUITING

    Córdoba, 5000, Argentina

    Contact

  • Sanatorio Parque S.A.

    RECRUITING

    Rosario, Santa Fe Province, S20000DSV, Argentina

    Contact

  • Santa Casa de Misericordia de Belo Horizonte

    RECRUITING

    Belo Horizonte, 30150, Brazil

    Contact

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

    Contact

  • Severance Hospital Yonsei Cancer Center

    RECRUITING

    Seoul, 03722, South Korea

    Contact

  • Shizuoka Cancer Center

    RECRUITING

    Nagaizumi-chō, 411-0934, Japan

    Contact

  • Siriraj Hospital Mahidol University

    RECRUITING

    Bangkok, 10700, Thailand

    Contact

  • Sotiria Thoracic Diseases Hospital of Athens

    RECRUITING

    Athens, 115 27, Greece

    Contact

  • Sunway Medical Centre

    RECRUITING

    Subang Jaya, 47500, Malaysia

    Contact

  • Sylvester Comprehensive Cancer Center Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

  • Szpital Specjalistyczny w Brzozowie

    RECRUITING

    Brzozów, 36-200, Poland

    Contact

  • Tan Tock Seng Hospital

    RECRUITING

    Singapore, 308433, Singapore

    Contact

  • The Cancer Institute Hospital of Japanese Foundation for Cancer Research

    RECRUITING

    Tokyo, 135-8550, Japan

    Contact

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

    Contact

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

  • The Royal Marsden NHS Foundation Trust

    RECRUITING

    London, SW3 6JJ, United Kingdom

    Contact

  • UOMi Cancer Center

    RECRUITING

    Barcelona, 08017, Spain

    Contact

  • UZ Leuven

    RECRUITING

    Leuven, 3000, Belgium

    Contact

  • University General Hospital of Larissa

    RECRUITING

    Larissa, 411 10, Greece

    Contact

  • University Medical Center Utrecht

    RECRUITING

    Utrecht, 3584, Netherlands

    Contact

  • University of California, Irvine Health

    RECRUITING

    Orange, California, 92868, United States

    Contact

  • University of Cincinnati Cancer Center

    RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact

  • University of Southern Denmark

    RECRUITING

    Odense, 5000, Denmark

    Contact

  • Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

  • Wakayama Medical University Hospital

    RECRUITING

    Wakayama, 641-0012, Japan

    Contact

  • Washington University Center for Advanced Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

  • Westmead Hospital

    RECRUITING

    Westmead, New South Wales, 2145, Australia

    Contact

  • Wiener Gesundheitsverbund

    RECRUITING

    Vienna, 1210, Austria

    Contact

  • Winship Cancer Institute of Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

  • Zanamed Medical Clinic Sp. z o.o.

    RECRUITING

    Lublin, 20-601, Poland

    Contact

Conditions

Explore the condition pages connected to this study.

ANAPLASTIC LYMPHOMA KINASE-POSITIVE NON SMALL CELL LUNG CANCER