First patients dosed in groundbreaking trial targeting a common Cancer-Causing gene

NCT ID NCT06364696

Summary

This is the first time a new drug called ASP4396 is being given to people. The study aims to find a safe dose and understand how the body handles it. It is for adults with advanced solid tumors that have spread and carry a specific genetic change called KRAS G12D, who have few other treatment options. The main goal is to check for side effects and see how well people tolerate the drug.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • NEXT Oncology Dallas

    Irving, Texas, 75039, United States

  • NEXT Oncology Virginia

    Fairfax, Virginia, 22031, United States

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    West Valley City, Utah, 84119, United States

  • University of Kansas Cancer Center

    Westwood, Kansas, 66205, United States

  • University of Rochester

    Rochester, New York, 14627, United States

Conditions

Explore the condition pages connected to this study.