New pill targets 'Undruggable' cancer driver in major trial

NCT ID NCT06959615

Recruiting now Disease control Sponsor: Jacobio Pharmaceuticals Co., Ltd. Source: ClinicalTrials.gov ↗

Summary

This study is testing a new oral drug, JAB-23E73, designed to block a common cancer-driving protein called KRAS. It aims to find a safe dose and see if the drug can shrink tumors in 334 adults with advanced solid tumors that have a KRAS gene change. The trial is in early phases, first focusing on safety and then expanding to see how well it works in specific cancers like lung cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Anhui Provincial Cancer Hospital
NOT_YET_RECRUITING

Hefei, Anhui, 230001, China
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100032, China
Beijing Chest Hospital
RECRUITING

Beijing, Beijing Municipality, 100032, China
Beijing Friendship Hospital, Capital Medical University
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100050, China
Fudan University Zhongshan Hospital
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Fujian cancer Hospital
NOT_YET_RECRUITING

Fuzhou, Fujian, 350014, China
Guangxi Medical University Cancer Hospital
RECRUITING

Nanning, Guangxi, 530012, China
Harbin Medical University Cancer Hospital
RECRUITING

Haerbin, Heilongjiang, 150081, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450003, China
Huashan Hospital Fudan University
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200040, China
Hunan Cancer Hospital
NOT_YET_RECRUITING

Changsha, Hunan, 200032, China
Jiangsu Cancer Hospital
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210009, China
Jiangsu Province Hospital
RECRUITING

Nanjing, Jiangsu, 210029, China
Nanjing Drum Tower Hospital
RECRUITING

Nanjing, Jiangsu, 210008, China
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
RECRUITING

Beijing, Beijing Municipality, 100021, China
National Cancer Center/Cancer Hospital- Langfang Campus, Chinese Academy of Medical Sciences and Peking Union Medical College
RECRUITING

Langfang, Hebei, 065000, China
Peking Union Medical College Hospital
RECRUITING

Beijing, Beijing Municipality, 100032, China
ShanXi Cancer Hospital
RECRUITING

Taiyuan, Shanxi, 650118, China
Shanghai Jiaotong University School of Medicine Ruijin Hospital
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200025, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
RECRUITING

Guangzhou, Guangdong, 510120, China
The First Affiliate of Soochow University
NOT_YET_RECRUITING

Suzhou, Jiangsu, 215006, China
The First Affiliated hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330006, China
The First Affiliated hospital of Xi'an Jiaotong University
NOT_YET_RECRUITING

Xi’an, Shanxi, 710061, China
The First Affiliated hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China
The First Hospital of China Medical University
RECRUITING

Shenyang, Liaoning, 110001, China
The Second Affiliate Hospital Zhejiang University School of Medicine
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310009, China
Tianjin Medical University Cancer Institute&Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300211, China
Tongji Hospital
NOT_YET_RECRUITING

Wuhan, Hubei, 430030, China
West China Hospital, Sichuan University
NOT_YET_RECRUITING

Chengdu, Sichuan, 610041, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, 310005, China
Zhejiang Provincial People's Hospital
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310014, China
Zhongnan Hospital of Wuhan University
RECRUITING

Wuhan, Hubei, 430071, China

Conditions

Explore the condition pages connected to this study.

ADVANCED SOLID TUMOR