Scientists test new pill to target 'Undruggable' cancer driver
NCT ID NCT04973163
Summary
This is an early safety study for adults with advanced solid tumors (like lung or colorectal cancer) that have a specific KRAS G12C mutation and have stopped responding to standard treatments. Researchers are testing a new oral drug, BI 1823911, for the first time in people, both alone and combined with another drug, to find the safest dose and see if it can shrink tumors. Participants take daily pills and are closely monitored for side effects and tumor changes.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brussels - HOSP Jules Bordet
Anderlecht/Brussels-Capital, 1070, Belgium
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Edegem - UNIV UZ Antwerpen
Edegem/Antwerpen, 2650, Belgium
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Hospital Universitari Vall D Hebron
Barcelona, 08035, Spain
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10021, United States
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Sarah Cannon Research Institute at Mary Crowley
Dallas, Texas, 75230, United States
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The Christie
Manchester, M20 4BX, United Kingdom
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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UZ Leuven
Leuven/Vlaams-Brabant, 3000, Belgium
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Universitair Ziekenhuis Gent
Gent/Oost-Vlaanderen, 9000, Belgium
Conditions
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