Hope for kidney cancer: new drug cocktail shows promise in Late-Stage trial

NCT ID NCT05899049

First seen Nov 10, 2025 · Last updated May 12, 2026 · Updated 18 times

Summary

This study tests if adding a new drug (belzutifan) or a different immunotherapy combo (MK-1308A) to standard treatment helps people with advanced clear cell kidney cancer live longer or slow their cancer. About 249 Chinese adults who have not had prior treatment for advanced disease will take part. The goal is to see if these combinations work better than the current standard therapy.

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Contacts and locations

Locations

  • Beijing Cancer hospital-Renal carcinoma and melanoma ( Site 6000)

    Beijing, Beijing Municipality, 100142, China

  • Chongqing University Cancer Hospital ( Site 6009)

    Chongqing, Chongqing Municipality, 400030, China

  • Guangzhou First People's Hospital ( Site 6007)

    Guangzhou, Guangdong, 510180, China

  • Henan Cancer Hospital-Urology ( Site 6006)

    Zhengzhou, Henan, 450008, China

  • Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S

    Nanjing, Jiangsu, 210000, China

  • Ningbo First Hospital-Urology ( Site 6028)

    Ningbo, Zhejiang, 315010, China

  • SUN YAT-SEN UNIVERSITY CANCER CENTRE ( Site 6003)

    Guangzhou, Guangdong, 510060, China

  • The First Affiliated Hospital of Guangzhou Medical University-Urology ( Site 6036)

    Guangzhou, Guangdong, 510120, China

  • The First Affiliated Hospital of Nanchang University ( Site 6019)

    Nanchang, Jiangxi, 330006, China

  • The First Affiliated Hospital of Wenzhou Medical University-Urology Surgery ( Site 6021)

    Wenzhou, Zhejiang, 325000, China

  • The First Affiliated Hospital of Xi'an Jiaotong University ( Site 6014)

    Xi'an, Shaanxi, 710061, China

  • The First Affiliated Hospital, Zhejiang University ( Site 6024)

    Hangzhou, Zhejiang, 310003, China

  • The First Hospital of Jiaxing ( Site 6033)

    Jiaxing, Zhejiang, 314001, China

  • The Second Affiliated Hospital of Soochow University-Urology ( Site 6025)

    Suzhou, Jiangsu, 215004, China

  • The Second Hospital of Tianjin Medical University ( Site 6032)

    Tianjin, Tianjin Municipality, 300211, China

  • West China Hospital Sichuan University-Urology Surgery ( Site 6016)

    Chengdu, Sichuan, 610041, China

  • Wuhan Union Hospital ( Site 6002)

    Wuhan, Hubei, 430022, China

Conditions

Explore the condition pages connected to this study.