Breakthrough trial aims to extend lives in aggressive stomach cancers

NCT ID NCT06532006

Recruiting now Disease control Sponsor: Shanghai Henlius Biotech Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 study is testing whether adding a new antibody drug called HLX22 to standard treatment helps people with advanced HER2-positive stomach or gastroesophageal cancer live longer without their cancer getting worse. About 550 adults with previously untreated, advanced cancer will receive either the new combination or standard treatment, and researchers will compare how long patients live and how well they tolerate the treatments. The goal is to find a more effective first-line therapy for this aggressive cancer type.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ANIMI - Unidade de Tratamento Oncologico
RECRUITING

Lages, Santa Catarina, 88501-003, Brazil
ASST Cremona
RECRUITING

Cremona, 80131, Italy
Advanced Research LLC
RECRUITING

Deerfield Beach, Florida, 33064, United States
Affiliated Hospital of Youjiang Medical University for Nationalities
RECRUITING

Baise City, China
Agioi Anargiroi General Oncology Hospital of Kifissia
RECRUITING

Kifissia, 14564, Greece
Agios Savvas Cancer Hospital (Saint Savvas Regional Anticancer Oncology Hospital of Athens)
RECRUITING

Athens, 11522, Greece
AidPort, Osrodek Badan Klinicznych
RECRUITING

Otwock, Poland
American Oncology Network Vista Oncology Division
RECRUITING

Olympia, Washington, 98502, United States
Ankara City Hospital
RECRUITING

Ankara, Turkey (Türkiye)
Ankara University Medicine Faculty Cebeci Hospital
RECRUITING

Ankara, Turkey (Türkiye)
Asan Medical Center
RECRUITING

Seoul, South Korea
Ataturk University Faculty Of Medicine Research Hospital Medical Oncology
RECRUITING

Erzurum, Turkey (Türkiye)
Azienda Ospedaliera San Sebastiano di Caserta
RECRUITING

Caserta, 81100, Italy
Azienda Ospedaliero Universitaria delle Marche
RECRUITING

Torrette, 60126, Italy
Azienda Sanitaria Universitaria Friuli Centrale (ASU FC) (Azienda Sanitaria Universitaria Integrata di Udine) (ASUIUD) (AOU Santa Maria della Misericordia di Udine) (AAS4 Friuli Centrale)
RECRUITING

Udine, 33100, Italy
BRCR Medical Center
RECRUITING

Plantation, Florida, 33322, United States
Balkan Oncology Hospital, Trakya University
RECRUITING

Edirne, Turkey (Türkiye)
Banner MD Anderson Cancer Center
RECRUITING

Greeley, Colorado, 80631, United States
Baskent University Adana Dr Turgut Noyan Research and Application Center
RECRUITING

Adana, Turkey (Türkiye)
Beijing Cancer Hospital
RECRUITING

Beijing, 100142, China

Contact
Beneficência Portuguesa de São Paulo
RECRUITING

San Pablo, SP, 01321-001, Argentina
Brazilian Institute for Cancer Control (IBCC)
RECRUITING

Vila Mariana, São Paulo, 04014-002, Brazil
CER - Centro de Rehabilitacion Medica San Juan
RECRUITING

San Juan, J5402 DIL, Argentina
Cancer Hospital Affiliated to Xinjiang Medical University
RECRUITING

Ürümqi, China
Cancer Hospital Chinese Academy of Medical Sciences
RECRUITING

Beijing, China
Cancer Hospital of Shandong First Medical University
RECRUITING

Jinan, China
Central Coast Local Health District (Gosford and Wyong Hospital)
RECRUITING

Gosford, Sydney, 2250, Australia
Centro Especializado en Oncologia de Precision
RECRUITING

Lima, Peru
Centro Gaúcho Integrado - Hospital Mãe de Deus
RECRUITING

Porto Alegre, Rio Grande do Sul, 90110-270, Brazil
Centro Médico Privado CEMAIC
NOT_YET_RECRUITING

Cordoba, Santa Fe Province, X5008HHW, Argentina
Centro de Investigacion Pergamino SA
RECRUITING

Buenos Aires, Buenos Aires, B2700, Argentina
Centro de Investigaciones Clinicas. Clinica Viedma S.A.
RECRUITING

Viedma, Río Negro Province, 8500, Argentina
Centro de Oncologia de Precision
RECRUITING

Santiago, Santiago Metropolitan, 7560908, Chile
Centrul de Oncologie Sfantu Nectarie
RECRUITING

Floreşti, Romania
Chungbuk National University Hospital
RECRUITING

Cheongju-si, South Korea
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Clinica Amethyst Radiotherapy
RECRUITING

Craiova, Romania
Clinica de Hematologia e Oncologia Viver
RECRUITING

Santa Maria, Rio Grande Do Sul (RS), 97015-450, Brazil
Comprehensive Cancer Centers Nevada
RECRUITING

Las Vegas, Nevada, 89169, United States
Concord Repatriation General Hospital
RECRUITING

Concord, Sydney, Australia
Dezhou Second People's hospital
RECRUITING

Dezhou, China
Dicle University Medical Faculty Oncology Hospital
RECRUITING

Diyarbakır, Turkey (Türkiye)
Europejskie Centrum Zdrowia Otwock Sp. Z.o.o.
RECRUITING

Skorzewo, Poland
Evangelisches Krankenhaus Bielefeld gGmbH (EvKB)
RECRUITING

Bielefeld, 33611, Germany
Evex Hospitals - Caucasus Medical Center
RECRUITING

Tbilisi, 186, Georgia
Exelsus
RECRUITING

San Miguel de Tucumán, 4000, Argentina
Florida Cancer Specialist - East
RECRUITING

West Palm Beach, Florida, 33401, United States
Florida Cancer Specialist - North
RECRUITING

St. Petersburg, Florida, 33705, United States
Florida Cancer Specialist - South
RECRUITING

Fort Myers, Florida, 33901, United States
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, China
Fujian Cancer Hospital
RECRUITING

Fuzhou, China
Fundacion Arturo Lopez Perez
RECRUITING

Santiago, 99010-080, Chile
Fundacion CENIT
RECRUITING

Buenos Aires, 1125, Argentina
Gansu Provincial Cancer Hospital
RECRUITING

Lanzhou, China
Gansu Provincial Hospital
RECRUITING

Lanzhou, China
Gansu Wuwei Tumour Hospital
RECRUITING

Lanzhou, China
General Hospital of Ningxia Medical University
RECRUITING

Yinchuan, China
GenesisCare Research
RECRUITING

Campbelltown, Sydney, 2560, Australia
Gifu University Hospital
RECRUITING

Gifu, Japan
Gruppo Humanitas - Humanitas Research Hospital (Istituto Clinico Humanitas)
RECRUITING

Rozzano, 20089, Italy
Gunma University Hospital
RECRUITING

Maebashi, Japan
Guthrie Medical Group, PC and Robert Packer Hospital (Guthrie Cancer Center - Sayre)
RECRUITING

Sayre, Pennsylvania, 18840, United States
Gyeongsang National University Hospital
RECRUITING

Jinju, South Korea
HCA Midwest Health
RECRUITING

Nashville, Tennessee, 60637, United States
Hamamatsu University Hospital
RECRUITING

Hamamatsu, Japan
Hamatologisch-Onkologischen Praxis Eppendorf (HOPE)
RECRUITING

Hamburg, 20249, Germany
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, China
Heping Hospital Affiliated to Changzhi Medical College
RECRUITING

Changzhi, China
Hiroshima City Hiroshima Citizens Hospital
RECRUITING

Hiroshima, Japan
Hokkaido University Hospital
RECRUITING

Sapporo, Japan
Holden Comprehensive Cancer Center - University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States
Hospital Alvaro Cunqueiro
RECRUITING

Vigo, Spain
Hospital Clinico Universitario de Valencia
RECRUITING

Valencia, Spain
Hospital General Universitario Gregorio Maranon
RECRUITING

Madrid, Spain
Hospital Santa Marcelina HSM
RECRUITING

São Paulo, 08270-120, Brazil
Hospital Universitario Central de Asturias
RECRUITING

Oviedo, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, Spain
Hospital Universitario Puerta de Hierro Majadahonda
RECRUITING

Majadahonda, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, Spain
Hospital de Clinicas de Porto Alegre (HCPA)
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hospital del Mar
RECRUITING

Barcelona, Spain
Hunan Cancer Hospital
RECRUITING

Changsha, China
Hyogo Cancer Center
RECRUITING

Akashi-shi, Hyōgo, Japan
IONC Instituto Oncologico de Cordoba
RECRUITING

Córdoba, 5000, Argentina
IP Clinic
RECRUITING

Lodz, Poland
Ibaraki Prefectural Central Hospital, Ibaraki Cancer Center
RECRUITING

Kasama-shi, Japan
Icegclinic
RECRUITING

Santiago, 8240000, Chile
Instiruto Nacional de Enfermedades Neoplasicas
RECRUITING

Lima, Peru
Institut Catala di Oncologia - Hospital Duran i Reynals
RECRUITING

Barcelona, Spain
Instituto San Marcos
RECRUITING

San Juan, J5400 EBB, Argentina
Instituto de Oncologia de Rosario
RECRUITING

Cordoba, Santa Fe Province, 2000, Argentina
Instituto de Oncologia do Paraná - IOP Pequisa
RECRUITING

Curitiba, Paraná (PR), 82305-100, Brazil
Instituto del Cancer RedSalud Vitacura
RECRUITING

Santiago, Santiago Metropolitan, 7630000, Chile
Instituto di Ricovero e Cura a Carattere Scientifico (IRCCS)
RECRUITING

San Giovanni Rotondo, 71013, Italy
Institutto Peruano de Oncologia y Radioterapia
RECRUITING

San Isidro, Peru
Ishikawa Prefectural Central Hospital
RECRUITING

Kanazawa, Japan
Izumi City General Hospital
RECRUITING

Izumi-shi, Japan
JSV VIAN- Caraps Medline
RECRUITING

Tbilisi, 159, Georgia
Jeonbuk National University Hospital
RECRUITING

Cheongju-si, South Korea
Jiangsu Province Hospital
RECRUITING

Nanjing, China
Kagawa University Hospital
RECRUITING

Takamatsu, Kagawa-ken, Japan
Kangbuk Samsung Hospital
RECRUITING

Seoul, South Korea
Kayseri Memorial Hospital
RECRUITING

Kayseri, Turkey (Türkiye)
Keiyukai Sapporo Hospital
RECRUITING

Sapporo, Japan
Klinikum St. Marien Amberg
RECRUITING

Amberg, 92224, Germany
Kocaeli University Hospital
RECRUITING

Kocaeli, Turkey (Türkiye)
Korea University Anam Hospital
RECRUITING

Seoul, South Korea
Korea University Guro Hospital
RECRUITING

Seoul, South Korea
Kreiskliniken Reutlingen gGmbH
RECRUITING

Reutlingen, 72764, Germany
LLC Todua Clinic
RECRUITING

Tbilisi, 112, Georgia
Liaoning Medical University Cancer Institute & Hospital
RECRUITING

Shenyang, China
Liuzhou Workers' Hospital
RECRUITING

Liuchow, China
Los Angeles Cancer Network
RECRUITING

Anaheim, California, 92801, United States
Ltd "New Hospitals"
RECRUITING

Tbilisi, 114, Georgia
Macquarie University
RECRUITING

North Ryde, Sydney, 2109, Australia
Maria Sklodowska-Curie National Cancer Research Institute
RECRUITING

Warsaw, Poland
Medical Center, Psychiko Clinic
RECRUITING

Athens, 11527, Greece
Medical Park Seyhan Hospital
RECRUITING

Adana, Turkey (Türkiye)
Medizinische Hochschule Hannover
RECRUITING

Hanover, 30625, Germany
Mianyang Central Hospital
RECRUITING

Mianyang, China
Mission Cancer + Blood (Exigent Network)
RECRUITING

Des Moines, Iowa, 50309, United States
Nanjing Drum Tower Hospital
RECRUITING

Nanjing, China
Napa Research
RECRUITING

Pompano Beach, Florida, 33064, United States
National Cancer Center Hospital
RECRUITING

Chuo Ku, Tokyo, Japan
National Hospital Organization Osaka National Hospital
RECRUITING

Chuo-ku Osaka-shi, Japan
Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68130, United States
Northwest Medical Specialties
RECRUITING

Tacoma, Washington, 98405, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
OPN - Oncology Physician Network (Los Alamitos)
RECRUITING

Los Alamitos, California, 90720, United States
Osaka International Cancer Institute
RECRUITING

Osaka, Japan
Osaka Keisatsu Hospital
RECRUITING

Osaka, Japan
Osaka Medical and Pharmaceutical University Hospital
RECRUITING

Takatsuki-shi, Japan
Osaki Citizen Hospital
RECRUITING

Osaki-shi, Japan
Panstwowy Instytut Medyczny MSWiA
RECRUITING

Warsaw, Poland
Papageorgiou General Hospital
RECRUITING

Thessaloniki, 56429, Greece
Peking Union Medical College Hospital
RECRUITING

Beijing, China
Peninsula Health-Frankston hospital
RECRUITING

Frankston, Melbourne, 3940, Australia
Personal Oncologia de Precisio e Personalizada
RECRUITING

Belo Horizonte, Minas Gerais, 30130 090, Brazil
Qinghai University Affiliated Hospital
RECRUITING

Xining, China
Real Hospital de Beneficencia Portuguesa
RECRUITING

Recife, Pernambuco, 52010-075, Brazil
Regional Institute of Gastroenterology and Hepatology
RECRUITING

Cluj-Napoca, Romania
Renji Hospital,Shanghai Jiao Tong University School of Medicine
RECRUITING

Shanghai, China
SLK-Kliniken Heilbronn GmbH
RECRUITING

Heilbronn, 74078, Germany
Saitama Cancer Center
RECRUITING

Saitama, Japan
Sakarya Training and Research Hospital
RECRUITING

Sakarya, Turkey (Türkiye)
Samsung Medical Center
RECRUITING

Seoul, South Korea
Sanatorio Plaza - Fundacion Pita
RECRUITING

Rosario, Santa Fe Province, 2000, Argentina
Sanatorio de la Mujer
RECRUITING

Rosario, Santa Fe Province, S2013, Argentina
Sc Sigmedical Srl
RECRUITING

Suceava, Romania
Seoul National University Hospital
RECRUITING

Seoul, South Korea
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, South Korea
Shanxi Cancer Hospital
RECRUITING

Taiyuan, China
Shizuoka General Hospital
RECRUITING

Shizuoka, Japan
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
RECRUITING

Chengdu, China
Sir Run Run Shaw Hospital (SRRSH), affiliated with the Zhejiang University School of Medicine
RECRUITING

Hangzhou, China
Sotiria General Hospital of Chest Diseases
RECRUITING

Athens, 11527, Greece
Spitalul Pelican
RECRUITING

Oradea, Romania
St. Vincent Hospital Melbourne
RECRUITING

Fitzroy, Melbourne, 3065, Australia
Suita Municipal Hospital
RECRUITING

Suita, Japan
Szpital Specjalistyczny Podkarpacki Osrodek Onkologiczny w Brzozowie
RECRUITING

Brzozów, Poland
Szpital Wojewodzki w Koszalinie im. Mikolaja Kopernika
RECRUITING

Koszalin, Poland
Tbilisi State Medical University and Ingorovka High Medical Technology University Clinic Ltd
RECRUITING

Tbilisi, 114, Georgia
Teine Keijinkai Hospital
RECRUITING

Sapporo, Japan
Tekirdag namik kemal university hospital medical oncology klinik
RECRUITING

Tekirdağ, Turkey (Türkiye)
Texas Oncology - Gulf Coast (SCRI)
RECRUITING

Webster, Texas, 77598, United States
Texas Oncology - West (SCRI)
RECRUITING

Abilene, Texas, 79606, United States
Texas Oncology Central South (SCRI)
RECRUITING

Austin, Texas, 78705, United States
Texas Oncology Northeast (SCRI)
RECRUITING

Denton, Texas, 76201, United States
The Affiliated Hospital of Qingdao University
RECRUITING

Qingdao, China
The Cancer Institute Hospital of JFCR
RECRUITING

Kōtoku, Japan
The Central Hospital of Shaoyang
RECRUITING

Shaoyang, China
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, China
The First Affiliated Hospital of Bengbu Medical University
RECRUITING

Bengbu, China
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, China
The First Affiliated Hospital of Henan University of Science
RECRUITING

Luoyang, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, China
The First Affiliated Hospital of Xiamen University
RECRUITING

Xiamen, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, China
The First Affiliated Hospital, Zhejiang University School of Medic
RECRUITING

Hangzhou, China
The First Hospital Of Lanzhou University
RECRUITING

Lanzhou, China
The First Hospital of Jilin University
RECRUITING

Changchun, China
The First People's Hospital of Changzhou
RECRUITING

Changzhou, China
The Fourth Hospital of Hebei Medical University
RECRUITING

Shijia Zhuang, China
The Second Hospital of Anhui Medical University
RECRUITING

Hefei, China
The Sixth Affiliated Hospital of Sun Yat-sen University
RECRUITING

Guangzhou, China
The University of Texas MD Anderson cancer Center
RECRUITING

Houston, Texas, 77030, United States
Tianjin Medical University Cancer Institute & Hospital
RECRUITING

Tianjin, China
Tochigi Cancer Center
RECRUITING

Utsunomiya, Japan
Toyonaka Municipal Hospital
RECRUITING

Toyonaka-shi, Japan
UPMC Hillman Cancer Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
Universita degli Studi della Campania "Luigi Vanvitelli" - Azienda Ospedaliera Universitaria
RECRUITING

Napoli, 80131, Italy
Universitaetsklinikum Carl-Gustav-Carus
RECRUITING

Dresden, 1307, Germany
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of the Sunshine Coast Clinical Trials, Sunshine Coast Haematology and Oncology Clinic
RECRUITING

Sunshine Coast, Queensland, 4556, Australia
Uniwersytecki Szpital Kliniczny Nr 1 w Lublinie
RECRUITING

Lublin, Poland
Uniwersyteckie Centrum Kliniczne
ENROLLING_BY_INVITATION

Gdansk, Poland
União Brasileira de Educação e Assistência
RECRUITING

Puerto Alegre, RS, 90610000, Argentina
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
Wakayama Medical University Hospital
RECRUITING

Wakayama, Japan
Washington University School of Medicine St. Louis
RECRUITING

St Louis, Missouri, 63110, United States
West China Hospital of Sichuan University
RECRUITING

Chengdu, China
West Virginia University Cancer Institute
RECRUITING

Morgantown, West Virginia, 26506, United States
Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka w S?upsku Sp. z o.o.
RECRUITING

Słupsk, Poland
Xuzhou Central Hospital
RECRUITING

Xuzhou, China
Yamagata Prefectural Central Hospital
RECRUITING

Yamagata, Japan
Yichang Central People's Hospital
RECRUITING

Yichang, China
Zhongshan City People's Hospital
RECRUITING

Guangdong, China

Conditions

Explore the condition pages connected to this study.

GASTRIC CANCER GASTROESOPHAGEAL JUNCTION CANCER HER2-POSITIVE GASTRIC CANCER MONOCLONAL ANTIBODY