New cancer pill targets Tough-to-Treat tumors

NCT ID NCT05593094

Summary

This early-stage study is testing a new oral medication called ZN-A-1041 for people with advanced HER2-positive cancers that have spread or returned after treatment. Researchers will give the drug alone or combined with other standard cancer therapies to about 210 participants to find safe doses and see if it helps control tumor growth. The study is specifically looking at cancers that have spread, including to the brain.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Arizona Clinical Research Center, Inc.;Hematology Oncology Physicians - Aoa

    Tucson, Arizona, 85712, United States

  • Asst Papa Giovanni XXIII

    Bergamo, Lombardy, 24127, Italy

  • Auckland City Hospital

    Auckland, 1023, New Zealand

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Centre Georges Francois Leclerc

    Dijon, 21000, France

  • Centre Léon Bérard Centre Régional de Lutte Contre Le Cancer Rhône Alpes

    Lyon, 69373, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Clatterbridge Cancer Centre

    Liverpool, Merseyside, L69 3GL, United Kingdom

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University School of Medicine

    Durham, North Carolina, 27710, United States

  • EDOG - Institut Claudius Regaud - PPDS

    Toulouse, Haute-Garonne, 31059, France

  • Fondazione Policlinico Universitario A Gemelli-Rome

    Magnago, Lombardy, 20020, Italy

  • Fundacion Instituto Valenciano de Oncologia (IVO)

    Valencia, 46009, Spain

  • Geelong Hospital

    Geelong, Victoria, 3220, Australia

  • Gustave Roussy

    Villejuif, 94800, France

  • Hospital Beata Maria Ana

    Madrid, 28007, Spain

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital Clinico San Carlos

    Madrid, 28040, Spain

  • Hospital Clinico Universitario de Santiago

    Santiago de Compostela, LA Coruna, 15706, Spain

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Ramon y Cajal

    A Gudiña, Orense, 32540, Spain

  • Hospital Universitario Virgen Macarena

    Seville, 41009, Spain

  • Hospital Universitario Virgen del Rocio

    Las Cabezas de San Juan, Sevilla, 41730, Spain

  • Hospital Universitario de Jaen

    Jaén, 23007, Spain

  • Institut Paoli-Calmettes

    Marseille, 13009, France

  • Institut de Cancerologie de l Ouest

    Saint-Herblain, 44805, France

  • Instituto Oncologico Dr. Rosell-Hospital Universitari Dexeus-Grupo Quironsalud

    Barcelona, 08028, Spain

  • Instituto de Investigacion Oncologica Vall dHebron (VHIO) - EPON

    Argentona, Barcelona, 08310, Spain

  • Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST S.r.l - PPDS

    Parma, Emilia-Romagna, 43126, Italy

  • MD Anderson Cancer Center

    Houston, Texas, 77030-4000, United States

  • Sunshine Hospital

    St Albans, Victoria, 3021, Australia

  • TOI Clinical Research

    Cerritos, California, 90703-2684, United States

  • The Christie

    Manchester, Lancashire, M20 4BX, United Kingdom

  • UCSF Helen Diller Family CCC

    San Francisco, California, 94158, United States

  • University of Michigan Hospital

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.