Breakthrough trial aims to extend lives in aggressive bile duct cancer

NCT ID NCT06282575

Recruiting now Disease control Sponsor: Jazz Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new targeted drug called zanidatamab to standard chemotherapy works better for people with advanced HER2-positive bile duct cancer. Researchers will compare the combination treatment against standard chemotherapy alone in 286 participants. The main goal is to see if the new combination helps people live longer without their cancer getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AIG Hospitals (A Unit of Asian Institute of Gastroenterology)
RECRUITING

Hyderabad, Telangana, 500032, India
AOU dell'Universit~ degli Studi della Campania Luigi Vanvitelli
RECRUITING

Napoli, 80131, Italy
AdventHealth Hematology and Oncology
RECRUITING

Orlando, Florida, 32804, United States
Aichi Cancer Center
RECRUITING

Nagoya, Aichi-ken, 464-8681, Japan
Akdeniz University Medical Faculty Hospital
RECRUITING

Antalya, 07070, Turkey (Türkiye)
Asan Medical Center
RECRUITING

Seoul, 5505, South Korea
Asklepios Tumorzentrum Hamburg, Asklepios Klinik Altona - Onkologie und Palliativmedizin mit Sektionen Hamatologie und Rheumatologie
RECRUITING

Hamburg, 22763, Germany
Atlantic Health System/Morristown Medical Center
ACTIVE_NOT_RECRUITING

Morristown, New Jersey, 07960, United States
Azienda Ospedaliera Universitaria Integrata Verona
RECRUITING

Verona, 37134, Italy
Azienda Ospedaliero - Universitaria Pisana
RECRUITING

Pisa, 56126, Italy
Azienda Ospedaliero Universitaria di Cagliari Presidio Ospedaliero Duilio Casula
RECRUITING

Monserrato, Cagliari, 9042, Italy
Azienda Sanitaria Universitaria Friuli Centrale - P.O. S. Maria della Misericordia
RECRUITING

Udine, 33100, Italy
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100142, China
Biocinetic Ltda
RECRUITING

Santiago, Santiago Metropolitan, 8320000, Chile
CAIPO Centro para la Atención Integral del Paciente Oncológico
RECRUITING

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
CHA Bundang Medical Center, CHA University
RECRUITING

Bundang-Gu, Seongnam-Si, Gyeonggi-do, 13496, South Korea
CHU Besancon
RECRUITING

Besançon, Cedex, 25030, France
CHU Brest Hôpital de la Cavale Blanche
RECRUITING

Brest, 29200, France
CHU Estaing
RECRUITING

Clermont-Ferrand, 63100, France
CHU Montepellier - Hôpital Saint Eloi
RECRUITING

Montpellier, 34000, France
CHU Poitiers
RECRUITING

Poitiers, 86000, France
CHU de Bordeaux - Hôpital Haut Leveque
RECRUITING

Pessac, Cedex, 33604, France
CHU de Toulouse- (Toulouse University Hospital Center)
RECRUITING

Toulouse, Cedex 9, 31059, France
Cancerstudieenheten Huddinge, Karolinska Universitetssjukhuset Huddinge
RECRUITING

Huddinge, 14186, Sweden
Centre Hospitalier de l'Universite de Montreal (CHUM)
RECRUITING

Montreal, Quebec, H2X 0C1, Canada
Centro Médico Privado CEMAIC
RECRUITING

Córdoba, X5008HHW, Argentina
Centro Médico en Oncología Clínica EXELSUS S.R.L
RECRUITING

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Centro de Investigacion y Especialidades Medicas (CDIEM)
RECRUITING

Santiago, Santiago Metropolitan, 7500859, Chile
Centro de Investigaciónes Clínicas - Clínica Viedma
RECRUITING

Viedma, Río Negro Province, R8500ACE, Argentina
Centrul De Oncologie "SF. Nectarie" S.R.L.
ACTIVE_NOT_RECRUITING

Craiova, Dolj, 200542, Romania
Centrul de Oncologie Euroclinic SRL
ACTIVE_NOT_RECRUITING

Iași, 700106, Romania
Champalimaud Clinical Center
RECRUITING

Lisbon, 1400-038, Portugal
Chang Gung Memorial Hospital Kaohsiung Branch of the Chang Gung Medical Foundation
RECRUITING

Kaohsiung City, 833, Taiwan
Chang Gung Memorial Hospital Linkou Branch of the Chang Gung Medical Foundation
RECRUITING

Taoyuan District, 333, Taiwan
Charité - Universitätsmedizin Berlin - Campus Virchow Klinikum, Medizinische Klinik mit Schwerpunkt Hamatologie und Tumorimmunologie
RECRUITING

Berlin, 13353, Germany
Chiba Cancer Center
RECRUITING

Chiba, Chiba, 260-8717, Japan
Chopda Medicare & Research Centre Pvt. Ltd - Magnum Heart Institute
RECRUITING

Nashik, Maharashtra, 422005, India
City of Hope(City of Hope National Medical Center, City of Hope Medical Center)
RECRUITING

Duarte, California, 91010, United States
Clinica Puerto Montt
RECRUITING

Port Montt, Los Lagos Region, 5507642, Chile
Clinica Universidad de Navarra
RECRUITING

Pamplona, 31008, Spain
Complejo Hospitalario Universitario de Santiago -Hospital Clinico Universitario de Santiago
RECRUITING

Santiago de Compostela, A Coruna, 15706, Spain
Comprehensive Cancer Center, Helsinki University Hospital
RECRUITING

Helsinki, 290, Finland
Docrates Cancer Center
RECRUITING

Helsinki, 180, Finland
Fakultni nemocnice Hradec Kralove, Klinika onkologie a radioterapie
ACTIVE_NOT_RECRUITING

Hradec Králové, 50005, Czechia
Fakultni nemocnice v Motole, Onkologicka klinika
ACTIVE_NOT_RECRUITING

Prague, 150 00, Czechia
Fakultní nemocnice Brno, Interní hematologická a onkologická klinika
ACTIVE_NOT_RECRUITING

Brno, 625 00, Czechia
Fondazione IRCCS Istituto Nazionale per lo studio e la cura dei Tumori
RECRUITING

Milan, 20133, Italy
Fondazione Policlinico Universitario Gemelli-IRCCS
RECRUITING

Roma, 00168, Italy
Fundación ARS Médica
RECRUITING

San Salvador de Jujuy, Jujuy Province, 4600, Argentina
Fundación Arturo López Pérez (FALP)
RECRUITING

Santiago, Santiago Metropolitan, 7500921, Chile
Fundação Doutor Amaral Carvalho - Hospital Amaral Carvalho
RECRUITING

Jaú, São Paulo, 17210-080, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto (FUNFARME)
RECRUITING

São José do Rio Preto, São Paulo, 15090-000, Brazil
Fundação Pio XII Hospital de Amor de Barretos
RECRUITING

Barretos, São Paulo, 14.784-400, Brazil
Gustave Roussy
RECRUITING

Villejuif, 94805, France
Hacettepe University Cancer Institute
RECRUITING

Ankara, Sihhiye, 06230, Turkey (Türkiye)
Hanyang University Seoul Hospital
WITHDRAWN

Seoul, 4763, South Korea
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150086, China
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States
Hokkaido University Hospital
RECRUITING

Sapporo, Hokkaidô, 060-8648, Japan
Hopital Henri Mondor
RECRUITING

Créteil, 94010, France
Hospital Beaujon University
RECRUITING

Clichy, 92110, France
Hospital Clinico Universidad de Chile
RECRUITING

Santiago, Santiago Metropolitan, 8380494, Chile
Hospital Italiano de Buenos Aires
RECRUITING

Ciudad Autónoma de Buenos Aires (caba), Buenos Altes, C1199ABB, Argentina
Hospital Nossa Senhora Da Conceição/Centro Integrado de Pesquisa em Oncologia CIPO-GHC
RECRUITING

Porto Alegre, 91350-200, Brazil
Hospital Oncologico, Puerto Rico Medical Center
RECRUITING

Rio Piedras, 935, Puerto Rico
Hospital Provincial Del Centenario
RECRUITING

Rosario, Santa Fe Province, 2000, Argentina
Hospital Regional Universitario de Malaga
RECRUITING

Málaga, 29010, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, 28048, Spain
Hospital Universitario Miguel Servet
RECRUITING

Zaragoza, 50009, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, 14004, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain
Hospital Universitario y Politecnico La Fe
RECRUITING

Valencia, 46026, Spain
Hospital de Clinicas de Porto Alegre - HCPA
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hunan Provincial People's Hospital
RECRUITING

Changsha, Hunan, 410016, China
IRCCS Ospedale Policlinico San Martino
RECRUITING

Genova, 16132, Italy
Imelda VZW
RECRUITING

Bonheiden, Antwerpen, 2820, Belgium
Instituo di Candiolo, Fondazione del Piemonte per l'Oncologia (IRCCS)
RECRUITING

Candiolo, Torino, 10060, Italy
Institut de Cancérologie de l'Ouest
RECRUITING

Saint-Herblain, 44805, France
Instituto Médico de la Fundación Estudios Clínicos
RECRUITING

Rosario, Santa Fe Province, S2013DTC, Argentina
Instituto Nacional de Cancer - INCA
RECRUITING

Rio de Janeiro, 20230-130, Brazil
Instituto Português de Oncologia Do Porto Francisco Gentil, EPE
RECRUITING

Porto, 4200-072, Portugal
Institutul Clinic Fundeni
ACTIVE_NOT_RECRUITING

Bucharest, 22328, Romania
Irmandade Da Santa Casa de Misericordia de Porto Alegre - ISCMPA
RECRUITING

Porto Alegrev, Rio Grande do Sul, 90020-170, Brazil
Istanbul University Cerrahpasa Medical Faculty Hospital/Clinical Research Center
RECRUITING

Istanbul, Fatih, 34096, Turkey (Türkiye)
Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy
James Lind Centro de Investigacion del Cancer
RECRUITING

Temuco, Región de la Araucanía, 4800827, Chile
Jilin Cancer Hospital
RECRUITING

Changchun, Jilin, 130000, China
KLES Dr Prabhakar Kore Hospital and Medical Research Centre
RECRUITING

Belagavi, Karnataka, 590010, India
Kagoshima University Hospital
RECRUITING

Kagoshima, Kagoshima-ken, 890-8520, Japan
Kanagawa Cancer Center
RECRUITING

Yokohama, Kanagawa, 241-8515, Japan
Kanazawa University Hospital
RECRUITING

Kanazawa, Ishikawa-ken, 9208641, Japan
Kaohsiung Medical University - Chung-Ho Memorial Hospital
RECRUITING

Kaohsiung City, 807, Taiwan
Korea University Anam Hospital
RECRUITING

Seoul, 2841, South Korea
Korea University Guro Hospital
RECRUITING

Seoul, 8308, South Korea
Krankenhaus Nordwest - Institut für Klinisch-Onkologische Forschung (IFK)
RECRUITING

Frankfurt am Main, Hesse, 60488, Germany
Kuopio University Hospital
RECRUITING

Kuopio, 70029, Finland
Kyorin University Hospital
RECRUITING

Mitaka-shi, Tokyo, 181-8611, Japan
Kyoto University Hospital
RECRUITING

Kyoto, Kyôto, 606-8507, Japan
LMU Universitätsklinikum München, Campus Großhadern, Medizinische Klinik und Poliklinik III - Hämatologie und Onkologie
RECRUITING

München, Bavaria, 81377, Germany
Laura and Isaac Perlmutter Cancer Center at NYU Langone - Ambulatory Care Center
RECRUITING

New York, New York, 10016, United States
Liga Norte Riograndense Contra O Cancer
RECRUITING

Natal, Rio Grande do Norte, 59062-000, Brazil
London Health Sciences Centre
RECRUITING

London, Ontario, NGA 5W9, Canada
Mahamana Pandit Madan Mohan Malviya Cancer Centre
RECRUITING

Varanasi, Uttar Pradesh, 221005, India
Max Super Speciality Hospital - Saket (a unit of Devki Devi foundation)
RECRUITING

New Delhi, 110017, India
Medizinische Hochschule Hannover - Klinik Fur Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie
RECRUITING

Hanover, Nieder-Sachsen, 30625, Germany
Memorial Sloan Kettering Cancer Centers
RECRUITING

New York, New York, 10022, United States
Mie University Hospital
RECRUITING

Tsu, Mie-ken, 514-8507, Japan
Military Medical Academy, Clinic for Gastroenterology and Hepatology
ACTIVE_NOT_RECRUITING

Belgrade, 11040, Serbia
Minnesota Oncology Hematology, P.A.
ACTIVE_NOT_RECRUITING

Maple Grove, Minnesota, 55369, United States
Mount Vernon Cancer Centre
RECRUITING

London, England, HA 6 2RN, United Kingdom
NHS Foundation Trust Royal Marsden Hospital
RECRUITING

London, England, SW3 6JJ, United Kingdom
National Cancer Center
RECRUITING

Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea
National Cancer Center Hospital
RECRUITING

Chuo-Ku, Tokyo, 104-0045, Japan
National Cancer Center Hospital East
RECRUITING

Kashiwa, Chiba, 277-8577, Japan
National Cheng Kung University Hospital
RECRUITING

Tainan, 704, Taiwan
National Hospital Organization Kyushu Cancer Center
RECRUITING

Fukuoka, Fukuoka, 811-1395, Japan
National Hospital Organization Shikoku Cancer Center
RECRUITING

Matsuyama, Ehime, 791-0280, Japan
National Taiwan University Cancer Center
RECRUITING

Taipei, 106, Taiwan
Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg
RECRUITING

Heidelberg, Baden-Wurttemberg, 69120, Germany
Niigata University Medical and Dental Hospital
RECRUITING

Niigata, Niigata, 951-8520, Japan
Norton Cancer Institute - Audubon
RECRUITING

Louisville, Kentucky, 40217, United States
Ochsner Clinic Foundation
RECRUITING

New Orleans, Louisiana, 70121, United States
Oncology Institute of Vojvodina, Internal Oncology Clinic
ACTIVE_NOT_RECRUITING

Kamenitz, 21204, Serbia
Oncovida
RECRUITING

Santiago, Santiago Metropolitan, 7500994, Chile
Onkologiska mottagningen, Sahlgrenska Universitetssjukhuset
RECRUITING

Gothenburg, 413 45, Sweden
Onkologiska mottagningen, Skånes Universitetssjukhus Malmö
ACTIVE_NOT_RECRUITING

Malmo, 205 02, Sweden
Osaka Prefectural Hospital Organization Osaka International Cancer Institute
RECRUITING

Osaka, Osaka, 541-8567, Japan
Osaka University Hospital
RECRUITING

Suita-Shi, Ôsaka, 565-0871, Japan
Pi Health Cancer Hospital
RECRUITING

Hyderabad, Telangana, 500032, India
Princess Margaret Cancer Centre - University Health Network
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Pusan National University Hospital
RECRUITING

Busan, 49241, South Korea
Rabin Medical Center, Bellinson Hospital
RECRUITING

Petah Tikva, 49100, Israel
Rajiv Gandhi Cancer Institute And Research Centre
RECRUITING

New Delhi, 110085, India
Rambam Health Care Campus
RECRUITING

Haifa, 3109601, Israel
Rocky Mountain Cancer Centers, LLP
ACTIVE_NOT_RECRUITING

Lone Tree, Colorado, 80124, United States
Royal Marsden Hospital NHS Foundation Trust
RECRUITING

Surrey, England, SM2 5PT, United Kingdom
SCRI Oncology Partners
ACTIVE_NOT_RECRUITING

Nashville, Tennessee, 37203, United States
Saint Francis Cancer Center
RECRUITING

Greenville, South Carolina, 29607, United States
Samsung Medical Center
RECRUITING

Seoul, 6351, South Korea
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 3080, South Korea
Servicios Médicos URUMED SpA
RECRUITING

Rancagua, Libertador Gen Bernardo O Higgins, 2820000, Chile
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, 3722, South Korea
Shandong Provincial Third Hospital
RECRUITING

Jinan, Shandong, 250000, China
Sichuan Cancer Hospital
RECRUITING

Chengdu, Sichuan, 610041, China
Spital Clinic Judetean de Urgenta Bihor
ACTIVE_NOT_RECRUITING

Oradea, Bihor County, 410169, Romania
Tata Memorial Hospital
RECRUITING

Mumbai, Maharashtra, 4000012, India
Technische Universität Dresden Medizinische Fakultät Carl Gustav Carus
RECRUITING

Dresden, Saxony, 01307, Germany
Tel Aviv Sourasky Medical Center (Ichilov)
RECRUITING

Tel Aviv, 6423906, Israel
Texas Oncology - DFW
ACTIVE_NOT_RECRUITING

Dallas, Texas, 75246, United States
The Cancer Institute Hospital of Japanese Foundation For Cancer Research
RECRUITING

Koto-Ku, Tokyo, 135-8550, Japan
The Chaim Sheba Medical Center, Tel Hashomer
RECRUITING

Ramat Gan, HaMerkaz, 5265601, Israel
The Christie NHS Foundation Trust
RECRUITING

Manchester, England, M20 4BX, United Kingdom
The First Affiliated Hospital of USTC(Anhui Provincial Hospital)
RECRUITING

Hefei, Anhui, 230036, China
The First Hospital of Lanzhou University
RECRUITING

Lanzhou, Gansu, 730000, China
The Hadassah University Medical Center, Ein Kerem Hospital
RECRUITING

Jerusalem, 91120, Israel
The Univerrsity of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
The University of Kansas Cancer Center - Westwood
RECRUITING

Westwood, Kansas, 66205, United States
The University of Tokyo Hospital
RECRUITING

Bunkyo-ku, Tokyo, 113-8655, Japan
Tohoku University Hospital
RECRUITING

Sendai, Miyagi, 980-8574, Japan
Trakya University Faculty of Medicine
RECRUITING

Edirne, 22030, Turkey (Türkiye)
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States
UZ Antwerpen
RECRUITING

Edegem, Antwerpen, 2650, Belgium
UZ Leuven
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium
Unidade Local de Saude de Almada-Seixal, E.P.E. - Hospital Garcia de Orta
RECRUITING

Almada, 2805-267, Portugal
Unidade Local de Saude de Coimbra, EPE - Hospitais da Universidade de Coimbra
RECRUITING

Coimbra, 3004-561, Portugal
Unidade Local de Saúde de São José - Hospital de Santo António dos Capuchos
RECRUITING

Lisbon, 1150-314, Portugal
University Clinical Center of Serbia, Clinic for Gastroenterohepatology
ACTIVE_NOT_RECRUITING

Belgrade, 11000, Serbia
University of Michigan Hospital
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
Universitätsklinikum Freiburg - Klinik für Innere Medizin II,
RECRUITING

Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Medizinische Klinik I (MKI)
RECRUITING

Lübeck, Schleswig-Holstein, 23562, Germany
Universitätsklinikum Tübingen - Medizinische Universitätsklinik, Innere Medizin I
RECRUITING

Tübingen, Baden-Wuttemberg, 72076, Germany
Vall d'Hebron Institute of Oncology/Hospital Universitari de Vall d'Hebron
RECRUITING

Barcelona, 8035, Spain
Veneto Institute of Oncology IOV - I.R.C.C.S.
RECRUITING

Padua, 35128, Italy
Virginia Commonwealth University, VCU Health
RECRUITING

Richmond, Virginia, 23219, United States
West China Hospital Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China
Western General Hospital, Edinburgh Cancer Centre
RECRUITING

Edinburgh, Scotland, EH4 2XU, United Kingdom
Winship Cancer Institute
RECRUITING

Atlanta, Georgia, 30322, United States
Yamaguchi University Hospital
RECRUITING

Ube-Shi, Yamaguchi, 755-8505, Japan
Zhongshan Hospital Fudan University
RECRUITING

Shanghai, 200032, China

Conditions

Explore the condition pages connected to this study.

BILIARY TRACT CANCER