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Weekly shot challenges daily injection in fight against aggressive liver disease

NCT ID NCT07200908

Recruiting now Disease control Sponsor: Mirum Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This global Phase 3 trial is testing whether a new weekly injection called brelovitug (BJT-778) works as well as or better than the current daily injection (bulevirtide) for treating chronic hepatitis D, a serious liver infection. About 172 participants will be randomly assigned to receive either the weekly injection for nearly two years or the daily injection for one year followed by the weekly shot. The main goal is to see which treatment better controls the virus and improves liver health.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Barts Health NHS Trust

    RECRUITING

    London, E12ES, United Kingdom

  • CHU Grenoble Alpes Hopital Nord Michallon

    RECRUITING

    La Tronche, 38700, France

  • Centre Hospitalier Universitaire De Rennes

    RECRUITING

    Rennes, 35000, France

  • Centrul Medical Unirea S.R.L

    RECRUITING

    Iași, Lasi, 700023, Romania

  • Chelsea and Westminster Hospital NHS Foundation Trust

    RECRUITING

    London, London, SW10 9NH, United Kingdom

  • Fakultni Nemocnice Brno

    RECRUITING

    Brno, Brno, 62500, Czechia

  • Fakultni Nemocnice Hradec Kralove

    RECRUITING

    Hradec Králové, Hradec Králové, 500 03, Czechia

  • Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, 20122, Italy

  • Goethe University Frankfurt

    RECRUITING

    Frankfurt, Frankfurt, 60590, Germany

  • HOCH Health Ostschweiz

    RECRUITING

    Sankt Gallen, St.Gallen, 95 9007, Switzerland

  • Hospital Clinic Provincial De Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hospital Universitari Vall D Hebron

    RECRUITING

    Barcelona, Barcelona, 08035, Spain

  • Hospital Universitario Marqués de Valdecilla

    RECRUITING

    Santander, 39008, Spain

  • Hospital Universitario Ramón y Cajal

    RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario Torrecardenas

    RECRUITING

    Almería, Almeria, 04009, Spain

  • Hospital Universitario Virgen de la Victoria

    RECRUITING

    Málaga, 29010, Spain

  • Hospital Universitario Álvaro Cunqueiro

    RECRUITING

    Vigo, 36312, Spain

  • Hull University Teaching Hospitals

    RECRUITING

    Cottingham, HU16 5JQ, United Kingdom

  • Hôpital Beaujon

    RECRUITING

    Clichy, 92110, France

  • Hôpital Estaing

    RECRUITING

    Clermont-Ferrand, 63000, France

  • Hôpital Pitié Salpêtrière

    NOT_YET_RECRUITING

    Paris, 75013, France

  • Hôpital Rangueil

    RECRUITING

    Toulouse, 31059, France

  • Hôpital de la Croix-Rousse

    RECRUITING

    Lyon, 69004, France

  • Hôpitaux Universitaires

    RECRUITING

    Geneva, Canton of Geneva, 1205, Switzerland

  • Institute For Clinical And Experimental Medicine

    RECRUITING

    Prague, Prague, 140 00, Czechia

  • Karolinska University Hospital

    RECRUITING

    Huddinge, 14186, Sweden

  • King's College Hospital NHS Foundation Trust

    RECRUITING

    London, SE5 9RS, United Kingdom

  • Klin Med s.r.o.

    RECRUITING

    Prague, Prague, 2 120 00, Czechia

  • Krajská nemocnice Liberec, a.s.

    RECRUITING

    Liberec, Liberec, 460 01, Czechia

  • Medical University of Graz

    RECRUITING

    Graz, 8036, Austria

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, 30625, Germany

  • National Institute Of Infectious Diseases

    RECRUITING

    Bucharest, Bucharest, 021105, Romania

  • National Institute of Infectious Diseases Prof Dr Matei Bals

    RECRUITING

    Bucharest, 021105, Romania

  • North Manchester General Hospital

    RECRUITING

    Manchester, Manchester, M8 5RB, United Kingdom

  • Queen Elizabeth Hospital Birmingham

    RECRUITING

    Birmingham, Birmingham, B15 2GW, United Kingdom

  • Rostock University Medical Center

    RECRUITING

    Rostock, Rostock, 18057, Germany

  • Site 512 Centre Hospitalier de Versailles _ Hopital Andre Magnot

    NOT_YET_RECRUITING

    Le Chesnay, 78157, France

  • Spitalul Clinic De Boli Infectioase Si Tropicale Dr. Victor Babes

    RECRUITING

    Bucharest, Bucharest, 030303, Romania

  • Spitalul Clinic de Boli Infectioase Constanta

    RECRUITING

    Constanța, 900709, Romania

  • University Hospital Henri Mondor - APHP

    RECRUITING

    Créteil, 94000, France

  • University Hospital Limoges

    RECRUITING

    Limoges, 87042, France

  • Universitätsklinikum Düsseldorf

    RECRUITING

    Düsseldorf, 40225, Germany

  • Universitätsklinikum St. Pölten

    RECRUITING

    Sankt Pölten, 3100, Austria

  • Universitätsspital Zürich

    RECRUITING

    Zurich, 8091, Switzerland

Conditions

Explore the condition pages connected to this study.

CHRONIC HEPATITIS D INFECTION