New drug combo challenges standard treatment for hepatitis d

NCT ID NCT07142811

Summary

This study is testing whether a new two-drug combination (Tobevibart+Elebsiran) works better than the current standard treatment (bulevirtide) for people with chronic hepatitis D virus (HDV) infection. About 100 adults with stable liver disease will receive either the new combination or the standard treatment for 48 weeks. Researchers will measure whether the virus becomes undetectable and monitor safety to see which approach is more effective.

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Contacts and locations

Locations

  • Investigative

    Valencia, 46014, Spain

  • Investigative Site

    Brussels, 1020, Belgium

  • Investigative Site

    Brussels, 1070, Belgium

  • Investigative Site

    Edegem, 2650, Belgium

  • Investigative Site

    Sofia, 1407, Bulgaria

  • Investigative Site

    Sofia, 1431, Bulgaria

  • Investigative Site

    Stara Zagora, 6003, Bulgaria

  • Investigative Site

    Clichy, 92110, France

  • Investigative Site

    Créteil, 94000, France

  • Investigative Site

    Limoges, 87042, France

  • Investigative Site

    Rennes, 35000, France

  • Investigative Site

    Toulouse, 31059, France

  • Investigative Site

    Hanover, 30625, Germany

  • Investigative Site

    Chisinau, 2025, Moldova

  • Investigative Site

    Amsterdam, 1081 HV, Netherlands

  • Investigative Site

    Nijmegen, 6525 GA, Netherlands

  • Investigative Site

    Rotterdam, 3015 GD, Netherlands

  • Investigative Site

    Karachi, 74800, Pakistan

  • Investigative Site

    Karachi, 75600, Pakistan

  • Investigative Site

    Lahore, 54800, Pakistan

  • Investigative Site

    Rawalpindi, 46000, Pakistan

  • Investigative Site

    Bucharest, 021105, Romania

  • Investigative Site

    Bucharest, 022328, Romania

  • Investigative Site

    Bucharest, 030303, Romania

  • Investigative Site

    Barcelona, 08028, Spain

  • Investigative Site

    Madrid, 28064, Spain

  • Investigative Site

    Kyiv, 01135, Ukraine

  • Investigative Site

    London, E1 1BB, United Kingdom

  • Investigative Site

    London, SE5 9RS, United Kingdom

  • Investigative Site

    Manchester, M8 5RB, United Kingdom

  • Investigative Site

    Nottingham, NG7 2UH, United Kingdom

Conditions

Explore the condition pages connected to this study.