New hope for tough stomach tumors: experimental drug combo enters human testing

NCT ID NCT06655246

Summary

This early-stage trial is testing the safety and initial effectiveness of a new oral drug, ziftomenib, when given alongside the standard drug imatinib. It is for adults with advanced gastrointestinal stromal tumors (GIST) whose cancer has continued to grow despite treatment with imatinib alone. The main goals are to find a safe dose and see if the combination can help control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Harvard University

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Cancer Center

    RECRUITING

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Cancer Center

    RECRUITING

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Cancer Center

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan-Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Sarah Cannon Research Institute

    RECRUITING

    Denver, Colorado, 80220, United States

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute

    RECRUITING

    Dallas, Texas, 75230, United States

  • Stanford Cancer Institute

    RECRUITING

    Palo Alto, California, 94304, United States

  • Temple University Health System

    RECRUITING

    Philadelphia, Pennsylvania, 19111, United States

  • Thomas Jefferson University

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • UCLA Santa Monica Medical Center

    RECRUITING

    Santa Monica, California, 90404, United States

  • University Of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • University of California, San Diego

    RECRUITING

    La Jolla, California, 92093, United States

  • University of Colorado Cancer Center

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90033, United States

  • University of Texas

    RECRUITING

    Houston, Texas, 77030, United States

  • University of Texas Health Science Center

    RECRUITING

    San Antonio, Texas, 78229, United States

  • University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

  • Yale University School of Medicine

    RECRUITING

    New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.