New pill aims to outperform standard heartburn drug in healing damaged esophagus

NCT ID NCT07037875

Summary

This study is testing if a new drug called linaprazan glurate works better than the common medication lansoprazole at healing damage in the esophagus caused by severe acid reflux (GERD). About 500 adults with confirmed esophageal damage will be randomly assigned to take one of two doses of the new drug or the standard drug for 8 weeks. Doctors will use camera exams to check if the damage has healed after 4 weeks and will monitor symptoms and safety.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • "MEDIS" Medical Center

    Bydgoszcz, 85-229, Poland

  • "Vita Longa" Non-Public Healthcare Facility, Limited Liability Company

    Katowice, 40-748, Poland

  • 20th Diagnostic Consultancy Center

    Sofia, Sofia City Province, 1618, Bulgaria

  • Bekes County Central Hospital Dr. Rethy Pal Member Hospital, 4th Department of Internal Medicine - Gastroenterology - Hepatology

    Békéscsaba, H-5600, Hungary

  • CLINSANTE Clinical Research Centre Ewa Galczak-Nowak, Malgorzata Trzaska

    Bydgoszcz, 85-794, Poland

  • Central Hospital of Northern Pest - Military Hospital, Department of Gastroenterology

    Budapest, H-1062, Hungary

  • Clinexpert Ltd. Budapest

    Budapest, H-1033, Hungary

  • Clinic for Internal Medicine Munich-Sued

    Munich, Bavaria, 81379, Germany

  • Cluj Napoca County Emergency Clinical Hospital, Internal Medicine III

    Cluj-Napoca, 400006, Romania

  • Colentina Clinical Hospital, Department of Gastroenterology

    Bucharest, 020125, Romania

  • Diagnosis - Consulting Centre 1

    Sliven, Bulgaria

  • Diagnostic Consultative Center - Focus-5

    Sofia, Sofia City Province, 1463, Bulgaria

  • Diagnostic and Consulting Center Alexandrovska

    Sofia, Sofia City Province, 1431, Bulgaria

  • Diakonie Hospital

    Mannheim, Baden-Wurttemberg, 68163, Germany

  • EMC Medical Institute Joint Stock Company, CERTUS Private Healthcare Facility Hospital No. 1, CERTUS Private Healthcare Facility Ambulatories

    Poznan, 60-309, Poland

  • ETG Warszawa

    Warsaw, 02-677, Poland

  • ETG Zamosc

    Zamość, 22-400, Poland

  • Endohope Morava s.r.o.

    Zábřeh, 78901, Czechia

  • Fejer County St. Gyorgy University Teaching Hospital, Department of Internal Medicine I

    Székesfehérvár, H-8000, Hungary

  • First Private Hospital Vratsa

    Vratsa, 3000, Bulgaria

  • FutureMeds Krakow

    Krakow, 31-501, Poland

  • FutureMeds Warsaw Center

    Warsaw, 00-215, Poland

  • FutureMeds Wroclaw

    Wroclaw, 53-673, Poland

  • Futuremeds Targowek

    Warsaw, 03-291, Poland

  • G1 Institute

    Budapest, 1036, Hungary

  • Gastromed Sp. z o.o. (LLC)

    Torun, 87-100, Poland

  • Gastromedic s.r.o.

    Pardubice, 53003, Czechia

  • Heves County Markhot Ferenc Teaching Hospital and Clinic, Department of General and Vascular Surgery

    Eger, H-3300, Hungary

  • Hospital Prachatice a.s.

    Prachatice, 38301, Czechia

  • Hospital of Brothers Hospitallers of Saint John of God In Lodz, Endoscopy Lab

    Lodz, 93-357, Poland

  • Independent Public Healthcare Facility University Hospital in Krakow, NSSU Endoscopy Department

    Krakow, 30-688, Poland

  • Independent Public Healthcare Facility, Norbert Barlicki University Teaching Hospital No. 1 of the Medical University in Lodz, Clinical Department of General Gastroenterology and Oncology

    Lodz, 90-153, Poland

  • Israeli - Georgian Medical Research Clinic Healthycore LLC

    Tbilisi, 0119, Georgia

  • JSC Georgian Clinics

    Kutaisi, 4600, Georgia

  • Janmrtelobis Sakhli LLC

    Tbilisi, 0144, Georgia

  • Javorszky Odon Hospital Vac, Department of Gastroenterology

    Vác, H-2600, Hungary

  • Khozrevanidze's Clinic

    Batumi, 6000, Georgia

  • LEPL The First University Clinic of Tbilisi State Medical University

    Tbilisi, 0178, Georgia

  • LLC Geo Hospitals

    Tbilisi, 0144, Georgia

  • LTD Aversi Clinic

    Marneuli, 3000, Georgia

  • LTD Aversi Clinic

    Tbilisi, 0160, Georgia

  • LTD Krol Medical Corporation

    Tbilisi, 0101, Georgia

  • Main Railway Outpatient Clinic Debrecen, Department of Gastroenterology

    Debrecen, H-4025, Hungary

  • Malkhaz Katsiashvili Multiprofile Emergency Medicine Center LLC

    Tbilisi, 0180, Georgia

  • Medical Care Unit Dachau

    Dachau, Bavaria, 85221, Germany

  • Medical Center "Orange"

    Sofia, Sofia City Province, 1343, Bulgaria

  • Medical Center Hera

    Sofia, Sofia City Province, 1510, Bulgaria

  • Medical Center Hera

    Kyustendil, 2500, Bulgaria

  • Medical Centre Oporow

    Wroclaw, 52-416, Poland

  • Military Hospital Brno, Internal Department

    Brno, 615 00, Czechia

  • Multiprofile Hospital For Active Treatment St. Ivan Rilski Gorna Oriahovitsa EOOD

    Gorna Oryahovitsa, 5100, Bulgaria

  • Multiprofile Hospital for Active Treatment "Sv. Ivan Rilski - 2003" OOD

    Dupnitsa, 2600, Bulgaria

  • Multiprofile Hospital for Active Treatment "Sveti Panteleymon"

    Plovdiv, 4000, Bulgaria

  • Multiprofile Hospital for Active Treatment - "Vita"

    Sofia, Sofia City Province, 1407, Bulgaria

  • NZOZ KERmed Medical Centre

    Bydgoszcz, 85-231, Poland

  • NZOZ Specialist Gastrology Centre GASTROMED

    Bialystok, 15-322, Poland

  • New health-CK, Kieltucki and partners g.p.

    Staszów, 28-200, Poland

  • Obuda Healthcare Center Ltd.

    Budapest, H-1036, Hungary

  • Oswiecim Clinical Trial Centre

    Oświęcim, 32-600, Poland

  • PreventaMed s.r.o.

    Olomouc, 779 00, Czechia

  • St. John Paul 2nd Municipal Hospital in Elblag, Department of Internal Diseases

    Elblag, 82-300, Poland

  • SurGal Clinic s.r.o.

    Brno, 602 00, Czechia

  • Synexus Hungary Ltd.

    Budapest, H-1036, Hungary

  • Synexus Polska Sp. z o.o. Branch in Gdansk

    Gdansk, 80-382, Poland

  • Synexus Polska Sp. z o.o. Branch in Katowice

    Katowice, 40-040, Poland

  • Synexus Polska Sp. z o.o. Branch in Poznan

    Poznan, 60-702, Poland

  • TVM MED SERV SRL, Medical Center for Gastroenterology, Hepatology and Digestive Endoscopy

    Cluj-Napoca, 400061, Romania

  • The New Hospitals

    Tbilisi, 0114, Georgia

  • Therapia Nova

    Warsaw, 01-595, Poland

  • University Hospital Brno

    Brno, 625 00, Czechia

  • University Multiprofile Hospital for Active Treatment "Sveta Marina"

    Pleven, 5800, Bulgaria

  • University Multiprofile Hospital for Active Treatment "Tsaritsa Yoanna - ISUL"

    Sofia, Sofia City Province, 1527, Bulgaria

  • University Multiprofile Hospital for Active Treatment and Emergency Medicine "N.I. Pirogov

    Sofia, Sofia City Province, 1606, Bulgaria

  • University of Szeged, Department of Internal Medicine- Western Site

    Szeged, H-6720, Hungary

  • WIP Warsaw IBD Point Profesor Kierkus

    Warsaw, 04-501, Poland

Conditions

Explore the condition pages connected to this study.