New pill aims to outperform standard heartburn drug in healing damaged esophagus
NCT ID NCT07037875
Summary
This study is testing if a new drug called linaprazan glurate works better than the common medication lansoprazole at healing damage in the esophagus caused by severe acid reflux (GERD). About 500 adults with confirmed esophageal damage will be randomly assigned to take one of two doses of the new drug or the standard drug for 8 weeks. Doctors will use camera exams to check if the damage has healed after 4 weeks and will monitor symptoms and safety.
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Contacts and locations
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Study contacts
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Contact
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Contact
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Locations
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"MEDIS" Medical Center
Bydgoszcz, 85-229, Poland
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"Vita Longa" Non-Public Healthcare Facility, Limited Liability Company
Katowice, 40-748, Poland
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20th Diagnostic Consultancy Center
Sofia, Sofia City Province, 1618, Bulgaria
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Bekes County Central Hospital Dr. Rethy Pal Member Hospital, 4th Department of Internal Medicine - Gastroenterology - Hepatology
Békéscsaba, H-5600, Hungary
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CLINSANTE Clinical Research Centre Ewa Galczak-Nowak, Malgorzata Trzaska
Bydgoszcz, 85-794, Poland
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Central Hospital of Northern Pest - Military Hospital, Department of Gastroenterology
Budapest, H-1062, Hungary
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Clinexpert Ltd. Budapest
Budapest, H-1033, Hungary
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Clinic for Internal Medicine Munich-Sued
Munich, Bavaria, 81379, Germany
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Cluj Napoca County Emergency Clinical Hospital, Internal Medicine III
Cluj-Napoca, 400006, Romania
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Colentina Clinical Hospital, Department of Gastroenterology
Bucharest, 020125, Romania
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Diagnosis - Consulting Centre 1
Sliven, Bulgaria
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Diagnostic Consultative Center - Focus-5
Sofia, Sofia City Province, 1463, Bulgaria
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Diagnostic and Consulting Center Alexandrovska
Sofia, Sofia City Province, 1431, Bulgaria
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Diakonie Hospital
Mannheim, Baden-Wurttemberg, 68163, Germany
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EMC Medical Institute Joint Stock Company, CERTUS Private Healthcare Facility Hospital No. 1, CERTUS Private Healthcare Facility Ambulatories
Poznan, 60-309, Poland
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ETG Warszawa
Warsaw, 02-677, Poland
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ETG Zamosc
Zamość, 22-400, Poland
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Endohope Morava s.r.o.
Zábřeh, 78901, Czechia
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Fejer County St. Gyorgy University Teaching Hospital, Department of Internal Medicine I
Székesfehérvár, H-8000, Hungary
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First Private Hospital Vratsa
Vratsa, 3000, Bulgaria
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FutureMeds Krakow
Krakow, 31-501, Poland
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FutureMeds Warsaw Center
Warsaw, 00-215, Poland
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FutureMeds Wroclaw
Wroclaw, 53-673, Poland
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Futuremeds Targowek
Warsaw, 03-291, Poland
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G1 Institute
Budapest, 1036, Hungary
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Gastromed Sp. z o.o. (LLC)
Torun, 87-100, Poland
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Gastromedic s.r.o.
Pardubice, 53003, Czechia
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Heves County Markhot Ferenc Teaching Hospital and Clinic, Department of General and Vascular Surgery
Eger, H-3300, Hungary
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Hospital Prachatice a.s.
Prachatice, 38301, Czechia
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Hospital of Brothers Hospitallers of Saint John of God In Lodz, Endoscopy Lab
Lodz, 93-357, Poland
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Independent Public Healthcare Facility University Hospital in Krakow, NSSU Endoscopy Department
Krakow, 30-688, Poland
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Independent Public Healthcare Facility, Norbert Barlicki University Teaching Hospital No. 1 of the Medical University in Lodz, Clinical Department of General Gastroenterology and Oncology
Lodz, 90-153, Poland
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Israeli - Georgian Medical Research Clinic Healthycore LLC
Tbilisi, 0119, Georgia
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JSC Georgian Clinics
Kutaisi, 4600, Georgia
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Janmrtelobis Sakhli LLC
Tbilisi, 0144, Georgia
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Javorszky Odon Hospital Vac, Department of Gastroenterology
Vác, H-2600, Hungary
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Khozrevanidze's Clinic
Batumi, 6000, Georgia
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LEPL The First University Clinic of Tbilisi State Medical University
Tbilisi, 0178, Georgia
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LLC Geo Hospitals
Tbilisi, 0144, Georgia
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LTD Aversi Clinic
Marneuli, 3000, Georgia
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LTD Aversi Clinic
Tbilisi, 0160, Georgia
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LTD Krol Medical Corporation
Tbilisi, 0101, Georgia
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Main Railway Outpatient Clinic Debrecen, Department of Gastroenterology
Debrecen, H-4025, Hungary
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Malkhaz Katsiashvili Multiprofile Emergency Medicine Center LLC
Tbilisi, 0180, Georgia
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Medical Care Unit Dachau
Dachau, Bavaria, 85221, Germany
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Medical Center "Orange"
Sofia, Sofia City Province, 1343, Bulgaria
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Medical Center Hera
Sofia, Sofia City Province, 1510, Bulgaria
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Medical Center Hera
Kyustendil, 2500, Bulgaria
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Medical Centre Oporow
Wroclaw, 52-416, Poland
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Military Hospital Brno, Internal Department
Brno, 615 00, Czechia
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Multiprofile Hospital For Active Treatment St. Ivan Rilski Gorna Oriahovitsa EOOD
Gorna Oryahovitsa, 5100, Bulgaria
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Multiprofile Hospital for Active Treatment "Sv. Ivan Rilski - 2003" OOD
Dupnitsa, 2600, Bulgaria
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Multiprofile Hospital for Active Treatment "Sveti Panteleymon"
Plovdiv, 4000, Bulgaria
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Multiprofile Hospital for Active Treatment - "Vita"
Sofia, Sofia City Province, 1407, Bulgaria
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NZOZ KERmed Medical Centre
Bydgoszcz, 85-231, Poland
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NZOZ Specialist Gastrology Centre GASTROMED
Bialystok, 15-322, Poland
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New health-CK, Kieltucki and partners g.p.
Staszów, 28-200, Poland
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Obuda Healthcare Center Ltd.
Budapest, H-1036, Hungary
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Oswiecim Clinical Trial Centre
Oświęcim, 32-600, Poland
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PreventaMed s.r.o.
Olomouc, 779 00, Czechia
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St. John Paul 2nd Municipal Hospital in Elblag, Department of Internal Diseases
Elblag, 82-300, Poland
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SurGal Clinic s.r.o.
Brno, 602 00, Czechia
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Synexus Hungary Ltd.
Budapest, H-1036, Hungary
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Synexus Polska Sp. z o.o. Branch in Gdansk
Gdansk, 80-382, Poland
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Synexus Polska Sp. z o.o. Branch in Katowice
Katowice, 40-040, Poland
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Synexus Polska Sp. z o.o. Branch in Poznan
Poznan, 60-702, Poland
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TVM MED SERV SRL, Medical Center for Gastroenterology, Hepatology and Digestive Endoscopy
Cluj-Napoca, 400061, Romania
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The New Hospitals
Tbilisi, 0114, Georgia
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Therapia Nova
Warsaw, 01-595, Poland
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University Hospital Brno
Brno, 625 00, Czechia
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University Multiprofile Hospital for Active Treatment "Sveta Marina"
Pleven, 5800, Bulgaria
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University Multiprofile Hospital for Active Treatment "Tsaritsa Yoanna - ISUL"
Sofia, Sofia City Province, 1527, Bulgaria
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University Multiprofile Hospital for Active Treatment and Emergency Medicine "N.I. Pirogov
Sofia, Sofia City Province, 1606, Bulgaria
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University of Szeged, Department of Internal Medicine- Western Site
Szeged, H-6720, Hungary
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WIP Warsaw IBD Point Profesor Kierkus
Warsaw, 04-501, Poland
Conditions
Explore the condition pages connected to this study.