Race against fungus: new drug battles deadly blood infection

NCT ID NCT05421858

Summary

This study is testing whether a new medication called fosmanogepix works as well as current standard treatments for serious Candida fungal infections in the blood or organs. About 450 adults with these life-threatening infections will receive either the new treatment or standard medications. The goal is to see if the new option is at least as effective at clearing the infection and keeping patients alive.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • "LAIKO" General Hospital

    RECRUITING

    Athens, 115 27, Greece

  • "Sotiria" Chest Diseases Hospital of Athens

    SUSPENDED

    Athens, 11527, Greece

  • AOU Senese

    RECRUITING

    Siena, 53100, Italy

  • Ajou University Hospital

    RECRUITING

    Suwon, 16499, South Korea

  • Amiens Picardie University Hospital - South, Intensive Care Unit (ICU)

    RECRUITING

    Amiens, 80054, France

  • Augusta University Medical Center

    RECRUITING

    Augusta, Georgia, 30912-5563, United States

  • Big Metropolitan Hospital Niguarda Regional Health Authority

    RECRUITING

    Milan, 20162, Italy

  • British Sanatorium SA

    RECRUITING

    Rosario, S2000CVB, Argentina

  • Buenos Aires Italian Hospital, Department of Infectious Diseases

    RECRUITING

    Buenos Aires, C1199ABB, Argentina

  • Cardiomet CEQUIN Foundation, Department of Nephrology

    RECRUITING

    Armenia, 630004, Colombia

  • Carilion Clinic

    RECRUITING

    Roanoke, Virginia, 24014, United States

  • Central Hospital Mendoza

    RECRUITING

    Mendoza, M5500IDN, Argentina

  • Central Hospital de San Isidro Melchor Posse

    RECRUITING

    Buenos Aires, B1641, Argentina

  • Chaim Sheba Medical Center, Department of Infectious Diseases

    RECRUITING

    Ramat Gan, 52621, Israel

  • China Medical University Hospital

    RECRUITING

    Taichung, 404327, Taiwan

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Cordoba Private University Hospital, Department of Infectious Diseases

    RECRUITING

    Córdoba, X5016KEH, Argentina

  • DMC Harper University Hospital

    RECRUITING

    Detroit, Michigan, 48201, United States

  • David Geffen School of Medicine at UCLA

    RECRUITING

    Los Angeles, California, 90095, United States

  • Edith Wolfson Medical Center, Department of Infectious Diseases

    RECRUITING

    Holon, 58100, Israel

  • Emory University Hospital - Clifton Road

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Erasme Hospital, Department of Infectious and Tropical Diseases

    RECRUITING

    Brussels, B-1070, Belgium

  • Eurohospital University Hospital

    RECRUITING

    Plovdiv, 4004, Bulgaria

  • Far Eastern Memorial Hospital

    RECRUITING

    New Taipei City, 220, Taiwan

  • Frankfurt University Clinic

    RECRUITING

    Frankfurt am Main, Hesse, 60590, Germany

  • General Hospital Saint-Jan

    RECRUITING

    Bruges, 8000, Belgium

  • General Hospital of Athens "Evangelismos", 5th Department of Internal Medicine and Infectious Diseases Unit

    RECRUITING

    Athens, PC 10676, Greece

  • General Hospital of Thessaloniki "Ippokratio"

    RECRUITING

    Thessaloniki, 54642, Greece

  • Giuliano Isontina University Health Authority

    RECRUITING

    Trieste, 34125, Italy

  • HC-UFPR

    RECRUITING

    Curitiba, Paraná, 80060-900, Brazil

  • Helen Joseph Hospital

    RECRUITING

    Johannesburg, 2092, South Africa

  • Henry Ford Hospital, Department of Medicine, Division of Infectious Diseases

    RECRUITING

    Detroit, Michigan, 48202, United States

  • High Technology Medical Institute S.A.S, IMAT S.A.S.

    RECRUITING

    Montería, 230002, Colombia

  • Hospital "S. Croce e Carle"

    RECRUITING

    Cuneo, 12100, Italy

  • Hospital Clinic of Barcelona, Department of Infectious Diseases

    SUSPENDED

    Barcelona, Catalonia, 08036, Spain

  • Hospital Favoriten, Department of Internal Medicine IV - Infectious Diseases and Tropical Medicine

    RECRUITING

    Vienna, 1100, Austria

  • Hospital Our Lady of Grace

    RECRUITING

    Curitiba, Paraná, 80810-040, Brazil

  • Hospital San Raffaele, IRCCS

    RECRUITING

    Milan, 20132, Italy

  • Hospital del Mar, Department of Infectious Diseases

    RECRUITING

    Barcelona, Catalonia, 08003, Spain

  • Houston Methodist Hospital - Texas Medical Center

    RECRUITING

    Houston, Texas, 77030, United States

  • IRCCS Policlinic Hospital San Martino

    RECRUITING

    Genoa, 16132, Italy

  • Indiana University Methodist Hospital

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Italian Hospital of La Plata, Department of Infectious Diseases

    RECRUITING

    La Plata, B1900, Argentina

  • Jessa Hospital

    RECRUITING

    Hasselt, 3500, Belgium

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • Kaohsiung Chang Gung Memorial Hospital

    RECRUITING

    Kaohsiung City, 833401, Taiwan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, 807377, Taiwan

  • Kepler University Hospital GmbH, Department of Pulmonology, Clinical Department of Infectious Diseases

    RECRUITING

    Linz, 4021, Austria

  • Kyungpook National University Hospital

    RECRUITING

    Daegu, 41944, South Korea

  • Linkou Chang Gung Memorial Hospital

    RECRUITING

    Taoyuan, 333, Taiwan

  • Lishui People's Hospital

    RECRUITING

    Lishui, 323000, China

  • Liuzhou People's Hospital

    RECRUITING

    Liuchow, 530021, China

  • Luz Castro de Gutierrez Medellin General Hospital, Research Center

    RECRUITING

    Medellín, 050015, Colombia

  • Maggiore Polyclinic Hospital, Foundation IRCCS Ca' Granda

    RECRUITING

    Milan, 20122, Italy

  • Maharaj Nakorn Chiang Mai Hospital

    RECRUITING

    Chiang Mai, 50200, Thailand

  • Marseille Nord University Hospitals - AP-HM, Medical Intensive Care Unit, Acute Respiratory Distress and Severe Infections

    SUSPENDED

    Marseille, 13015, France

  • Medical University Vienna

    RECRUITING

    Vienna, 1090, Austria

  • Milpark Hospital

    SUSPENDED

    Johannesburg, 2193, South Africa

  • Monash Medical Center Clayton

    RECRUITING

    Clayton, 3168, Australia

  • Nantes University Hospital Center - Hotel Dieu Hospital, Department of Infectious and Tropical Diseases

    RECRUITING

    Nantes, 44000, France

  • National University Hospital

    RECRUITING

    Singapore, 119074, Singapore

  • Pablo Tobon Uribe Hospital

    RECRUITING

    Medellín, 050034, Colombia

  • Peter MacCallum Cancer Center, State

    RECRUITING

    Melbourne, Victoria, 3000, Australia

  • Polyclinic San Matteo, IRCCS

    RECRUITING

    Pavia, 27100, Italy

  • Pontifical University Of Rio Grande Do Sul (PUCRS) - St. Luke Hospital

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90610-000, Brazil

  • Porto Alegre Clinical Hospital (HCPA), Infectious Diseases / Internal Medicine

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

  • Practice of R Moodley and MI Sarvan - Umhlanga

    RECRUITING

    Umhlanga, 4320, South Africa

  • Princess Alexandra Hospital

    RECRUITING

    Woolloongabba, Queensland, 4102, Australia

  • Qingyuan People's Hospital

    RECRUITING

    Qingyuan, 511518, China

  • Rambam Health Care Campus, Institute of Infectious Diseases

    RECRUITING

    Haifa, 3109601, Israel

  • Rennes University Hospital Center - Hospital Pontchaillou

    RECRUITING

    Rennes, 35000, France

  • Royal Melbourne Hospital

    RECRUITING

    Parkville, Victoria, 3050, Australia

  • Ryexo Clinical Research

    WITHDRAWN

    Pretoria, 0084, South Africa

  • Saint Luc University Hospital, Department of Internal Medicine

    RECRUITING

    Brussels, 1200, Belgium

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Santa Marcelina Hospital

    RECRUITING

    São Paulo, 08270-070, Brazil

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • Shamir Medical Center, Department of Infectious Diseases

    RECRUITING

    Ẕerifin, 7033001, Israel

  • Singapore General Hospital

    RECRUITING

    Singapore, 169608, Singapore

  • Siriraj Hospital

    RECRUITING

    Bangkok, 10700, Thailand

  • Somer Clinic

    RECRUITING

    Rionegro, 54040, Colombia

  • Songklanagarind Hospital

    RECRUITING

    Hat Yai, 90110, Thailand

  • Srinagarind Hospital

    RECRUITING

    Khon Kaen, 40002, Thailand

  • Taichung Veterans General Hospital

    RECRUITING

    Taichung, 407219, Taiwan

  • Taipei Medical University Hospital

    RECRUITING

    Taipei, 11000, Taiwan

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, 112201, Taiwan

  • Tan Tock Seng Hospital

    RECRUITING

    Singapore, 308433, Singapore

  • The 1st Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, 330006, China

  • The Alfred Hospital

    RECRUITING

    Melbourne, Victoria, 3004, Australia

  • The First Affiliated Hospital of Bengbu Medical College

    RECRUITING

    Bengbu, 233099, China

  • The Tel Aviv Sourasky Medical Center, Infectious Diseases Unit

    RECRUITING

    Tel Aviv, 6423906, Israel

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

  • Tours Regional University Hospital Center

    RECRUITING

    Tours, 37000, France

  • Tzaneio General Hospital

    SUSPENDED

    Piraeus, 185 36, Greece

  • UC Davis Medical Center

    RECRUITING

    Sacramento, California, 95817, United States

  • UCL Mont-Godinne University Hospitals

    SUSPENDED

    Yvoir, 5530, Belgium

  • UPMC Presbyterian

    RECRUITING

    Pittsburgh, Pennsylvania, 15213-2582, United States

  • University Hospital Brussels

    RECRUITING

    Brussels, 1090, Belgium

  • University Hospital Cologne, Department of Internal Medicine I, Clinical Study Centre II for Infectious Diseases

    RECRUITING

    Cologne, North Rhine-Westphalia, 50937, Germany

  • University Hospital Cruces

    RECRUITING

    Barakaldo, 48903, Spain

  • University Hospital Giessen and Marburg GmbH

    RECRUITING

    Giessen, Hesse, 35392, Germany

  • University Hospital Graz, Department of Internal Medicine

    RECRUITING

    Graz, 1100, Austria

  • University Hospital Heidelberg, Clinic for Anesthesiology

    RECRUITING

    Heidelberg, 69120, Germany

  • University Hospital Nuestra Senora de Valme

    RECRUITING

    Seville, Andalusia, 41014, Spain

  • University Hospital Ramon y Cajal, Department of Infectious Diseases

    RECRUITING

    Madrid, Madrid, 28034, Spain

  • University Hospital Regensburg

    RECRUITING

    Regensburg, Bavaria, 93053, Germany

  • University Hospital Ulm, Comprehensive Infectious Diseases Center Ulm (CIDCU)

    RECRUITING

    Ulm, Baden-Wurttemberg, 89081, Germany

  • University Hospital Vall d'Hebron, Intensive Care Unit (ICU)

    RECRUITING

    Barcelona, Catalonia, 08035, Spain

  • University Hospital Virgen Macarena

    RECRUITING

    Seville, Andalusia, 41009, Spain

  • University Hospital of Pisa

    RECRUITING

    Pisa, 56124, Italy

  • University Hospitals Leuven, Campus Gasthuisberg, Department of Infectious Diseases

    RECRUITING

    Leuven, 3000, Belgium

  • University Medical Center "N. I. Pirogov", Burns and Plastic Surgery Clinic

    RECRUITING

    Sofia, 1606, Bulgaria

  • University Medical Center "N. I. Pirogov", Clinic of Purulent-Septic Surgery

    RECRUITING

    Sofia, 1606, Bulgaria

  • University Polyclinic Hospital of Modena

    RECRUITING

    Modena, 41124, Italy

  • University of Alabama at Birmingham School of Medicine, Department of Medicine

    RECRUITING

    Birmingham, Alabama, 35294-0006, United States

  • University of Kentucky College of Medicine

    RECRUITING

    Lexington, Kentucky, 40506, United States

  • University of Michigan Health System (UMHS) - A. Alfred Taubman Health Care Center

    RECRUITING

    Ann Arbor, Michigan, 48109-5000, United States

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • University of Pennsylvania School of Medicine

    RECRUITING

    Philadelphia, Pennsylvania, 19104-6243, United States

  • University of Pretoria / Steve Biko Academic Hospital

    RECRUITING

    Pretoria, 0084, South Africa

  • University of Texas Health Science Center at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Vajira Hospital

    RECRUITING

    Bangkok, 10300, Thailand

  • Victor Dupouy Hospital Center Argenteuil, Intensive Care Unit

    RECRUITING

    Argenteuil, 95107, France

  • Washington University School of Medicine, Infectious Diseases Clinical Research Unit

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medical College - NewYork-Presbyterian Hospital

    RECRUITING

    New York, New York, 10065, United States

  • Westmead Hospital

    RECRUITING

    Sydney, New South Wales, 2145, Australia

  • Wuxi People's Hospital

    RECRUITING

    Wuxi, 214023, China

  • Zhejiang Provincal Hospital of Chinese Medicine

    RECRUITING

    Hangzhou, 310006, China

  • Zhejiang Provincial People's Hospital

    RECRUITING

    Hangzhou, 310014, China

Conditions

Explore the condition pages connected to this study.