Race against fungus: new drug battles deadly blood infection
NCT ID NCT05421858
Summary
This study is testing whether a new medication called fosmanogepix works as well as current standard treatments for serious Candida fungal infections in the blood or organs. About 450 adults with these life-threatening infections will receive either the new treatment or standard medications. The goal is to see if the new option is at least as effective at clearing the infection and keeping patients alive.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Contact
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Locations
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"LAIKO" General Hospital
RECRUITINGAthens, 115 27, Greece
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"Sotiria" Chest Diseases Hospital of Athens
SUSPENDEDAthens, 11527, Greece
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AOU Senese
RECRUITINGSiena, 53100, Italy
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Ajou University Hospital
RECRUITINGSuwon, 16499, South Korea
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Amiens Picardie University Hospital - South, Intensive Care Unit (ICU)
RECRUITINGAmiens, 80054, France
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Augusta University Medical Center
RECRUITINGAugusta, Georgia, 30912-5563, United States
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Big Metropolitan Hospital Niguarda Regional Health Authority
RECRUITINGMilan, 20162, Italy
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British Sanatorium SA
RECRUITINGRosario, S2000CVB, Argentina
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Buenos Aires Italian Hospital, Department of Infectious Diseases
RECRUITINGBuenos Aires, C1199ABB, Argentina
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Cardiomet CEQUIN Foundation, Department of Nephrology
RECRUITINGArmenia, 630004, Colombia
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Carilion Clinic
RECRUITINGRoanoke, Virginia, 24014, United States
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Central Hospital Mendoza
RECRUITINGMendoza, M5500IDN, Argentina
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Central Hospital de San Isidro Melchor Posse
RECRUITINGBuenos Aires, B1641, Argentina
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Chaim Sheba Medical Center, Department of Infectious Diseases
RECRUITINGRamat Gan, 52621, Israel
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China Medical University Hospital
RECRUITINGTaichung, 404327, Taiwan
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City of Hope
RECRUITINGDuarte, California, 91010, United States
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Cordoba Private University Hospital, Department of Infectious Diseases
RECRUITINGCórdoba, X5016KEH, Argentina
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DMC Harper University Hospital
RECRUITINGDetroit, Michigan, 48201, United States
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David Geffen School of Medicine at UCLA
RECRUITINGLos Angeles, California, 90095, United States
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Edith Wolfson Medical Center, Department of Infectious Diseases
RECRUITINGHolon, 58100, Israel
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Emory University Hospital - Clifton Road
RECRUITINGAtlanta, Georgia, 30322, United States
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Erasme Hospital, Department of Infectious and Tropical Diseases
RECRUITINGBrussels, B-1070, Belgium
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Eurohospital University Hospital
RECRUITINGPlovdiv, 4004, Bulgaria
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Far Eastern Memorial Hospital
RECRUITINGNew Taipei City, 220, Taiwan
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Frankfurt University Clinic
RECRUITINGFrankfurt am Main, Hesse, 60590, Germany
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General Hospital Saint-Jan
RECRUITINGBruges, 8000, Belgium
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General Hospital of Athens "Evangelismos", 5th Department of Internal Medicine and Infectious Diseases Unit
RECRUITINGAthens, PC 10676, Greece
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General Hospital of Thessaloniki "Ippokratio"
RECRUITINGThessaloniki, 54642, Greece
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Giuliano Isontina University Health Authority
RECRUITINGTrieste, 34125, Italy
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HC-UFPR
RECRUITINGCuritiba, Paraná, 80060-900, Brazil
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Helen Joseph Hospital
RECRUITINGJohannesburg, 2092, South Africa
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Henry Ford Hospital, Department of Medicine, Division of Infectious Diseases
RECRUITINGDetroit, Michigan, 48202, United States
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High Technology Medical Institute S.A.S, IMAT S.A.S.
RECRUITINGMontería, 230002, Colombia
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Hospital "S. Croce e Carle"
RECRUITINGCuneo, 12100, Italy
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Hospital Clinic of Barcelona, Department of Infectious Diseases
SUSPENDEDBarcelona, Catalonia, 08036, Spain
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Hospital Favoriten, Department of Internal Medicine IV - Infectious Diseases and Tropical Medicine
RECRUITINGVienna, 1100, Austria
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Hospital Our Lady of Grace
RECRUITINGCuritiba, Paraná, 80810-040, Brazil
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Hospital San Raffaele, IRCCS
RECRUITINGMilan, 20132, Italy
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Hospital del Mar, Department of Infectious Diseases
RECRUITINGBarcelona, Catalonia, 08003, Spain
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Houston Methodist Hospital - Texas Medical Center
RECRUITINGHouston, Texas, 77030, United States
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IRCCS Policlinic Hospital San Martino
RECRUITINGGenoa, 16132, Italy
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Indiana University Methodist Hospital
RECRUITINGIndianapolis, Indiana, 46202, United States
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Italian Hospital of La Plata, Department of Infectious Diseases
RECRUITINGLa Plata, B1900, Argentina
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Jessa Hospital
RECRUITINGHasselt, 3500, Belgium
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Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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Kaohsiung Chang Gung Memorial Hospital
RECRUITINGKaohsiung City, 833401, Taiwan
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Kaohsiung Medical University Chung-Ho Memorial Hospital
RECRUITINGKaohsiung City, 807377, Taiwan
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Kepler University Hospital GmbH, Department of Pulmonology, Clinical Department of Infectious Diseases
RECRUITINGLinz, 4021, Austria
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Kyungpook National University Hospital
RECRUITINGDaegu, 41944, South Korea
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Linkou Chang Gung Memorial Hospital
RECRUITINGTaoyuan, 333, Taiwan
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Lishui People's Hospital
RECRUITINGLishui, 323000, China
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Liuzhou People's Hospital
RECRUITINGLiuchow, 530021, China
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Luz Castro de Gutierrez Medellin General Hospital, Research Center
RECRUITINGMedellín, 050015, Colombia
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Maggiore Polyclinic Hospital, Foundation IRCCS Ca' Granda
RECRUITINGMilan, 20122, Italy
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Maharaj Nakorn Chiang Mai Hospital
RECRUITINGChiang Mai, 50200, Thailand
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Marseille Nord University Hospitals - AP-HM, Medical Intensive Care Unit, Acute Respiratory Distress and Severe Infections
SUSPENDEDMarseille, 13015, France
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Medical University Vienna
RECRUITINGVienna, 1090, Austria
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Milpark Hospital
SUSPENDEDJohannesburg, 2193, South Africa
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Monash Medical Center Clayton
RECRUITINGClayton, 3168, Australia
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Nantes University Hospital Center - Hotel Dieu Hospital, Department of Infectious and Tropical Diseases
RECRUITINGNantes, 44000, France
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National University Hospital
RECRUITINGSingapore, 119074, Singapore
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Pablo Tobon Uribe Hospital
RECRUITINGMedellín, 050034, Colombia
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Peter MacCallum Cancer Center, State
RECRUITINGMelbourne, Victoria, 3000, Australia
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Polyclinic San Matteo, IRCCS
RECRUITINGPavia, 27100, Italy
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Pontifical University Of Rio Grande Do Sul (PUCRS) - St. Luke Hospital
RECRUITINGPorto Alegre, Rio Grande do Sul, 90610-000, Brazil
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Porto Alegre Clinical Hospital (HCPA), Infectious Diseases / Internal Medicine
RECRUITINGPorto Alegre, Rio Grande do Sul, 90035-903, Brazil
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Practice of R Moodley and MI Sarvan - Umhlanga
RECRUITINGUmhlanga, 4320, South Africa
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Princess Alexandra Hospital
RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Qingyuan People's Hospital
RECRUITINGQingyuan, 511518, China
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Rambam Health Care Campus, Institute of Infectious Diseases
RECRUITINGHaifa, 3109601, Israel
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Rennes University Hospital Center - Hospital Pontchaillou
RECRUITINGRennes, 35000, France
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Royal Melbourne Hospital
RECRUITINGParkville, Victoria, 3050, Australia
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Ryexo Clinical Research
WITHDRAWNPretoria, 0084, South Africa
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Saint Luc University Hospital, Department of Internal Medicine
RECRUITINGBrussels, 1200, Belgium
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Samsung Medical Center
RECRUITINGSeoul, 06351, South Korea
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Santa Marcelina Hospital
RECRUITINGSão Paulo, 08270-070, Brazil
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Severance Hospital, Yonsei University Health System
RECRUITINGSeoul, 03722, South Korea
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Shamir Medical Center, Department of Infectious Diseases
RECRUITINGẔerifin, 7033001, Israel
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Singapore General Hospital
RECRUITINGSingapore, 169608, Singapore
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Siriraj Hospital
RECRUITINGBangkok, 10700, Thailand
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Somer Clinic
RECRUITINGRionegro, 54040, Colombia
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Songklanagarind Hospital
RECRUITINGHat Yai, 90110, Thailand
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Srinagarind Hospital
RECRUITINGKhon Kaen, 40002, Thailand
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Taichung Veterans General Hospital
RECRUITINGTaichung, 407219, Taiwan
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Taipei Medical University Hospital
RECRUITINGTaipei, 11000, Taiwan
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Taipei Veterans General Hospital
RECRUITINGTaipei, 112201, Taiwan
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Tan Tock Seng Hospital
RECRUITINGSingapore, 308433, Singapore
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The 1st Affiliated Hospital of Nanchang University
RECRUITINGNanchang, 330006, China
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The Alfred Hospital
RECRUITINGMelbourne, Victoria, 3004, Australia
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The First Affiliated Hospital of Bengbu Medical College
RECRUITINGBengbu, 233099, China
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The Tel Aviv Sourasky Medical Center, Infectious Diseases Unit
RECRUITINGTel Aviv, 6423906, Israel
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The University of Texas Health Science Center at Houston
RECRUITINGHouston, Texas, 77030, United States
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Tours Regional University Hospital Center
RECRUITINGTours, 37000, France
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Tzaneio General Hospital
SUSPENDEDPiraeus, 185 36, Greece
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UC Davis Medical Center
RECRUITINGSacramento, California, 95817, United States
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UCL Mont-Godinne University Hospitals
SUSPENDEDYvoir, 5530, Belgium
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UPMC Presbyterian
RECRUITINGPittsburgh, Pennsylvania, 15213-2582, United States
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University Hospital Brussels
RECRUITINGBrussels, 1090, Belgium
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University Hospital Cologne, Department of Internal Medicine I, Clinical Study Centre II for Infectious Diseases
RECRUITINGCologne, North Rhine-Westphalia, 50937, Germany
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University Hospital Cruces
RECRUITINGBarakaldo, 48903, Spain
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University Hospital Giessen and Marburg GmbH
RECRUITINGGiessen, Hesse, 35392, Germany
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University Hospital Graz, Department of Internal Medicine
RECRUITINGGraz, 1100, Austria
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University Hospital Heidelberg, Clinic for Anesthesiology
RECRUITINGHeidelberg, 69120, Germany
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University Hospital Nuestra Senora de Valme
RECRUITINGSeville, Andalusia, 41014, Spain
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University Hospital Ramon y Cajal, Department of Infectious Diseases
RECRUITINGMadrid, Madrid, 28034, Spain
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University Hospital Regensburg
RECRUITINGRegensburg, Bavaria, 93053, Germany
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University Hospital Ulm, Comprehensive Infectious Diseases Center Ulm (CIDCU)
RECRUITINGUlm, Baden-Wurttemberg, 89081, Germany
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University Hospital Vall d'Hebron, Intensive Care Unit (ICU)
RECRUITINGBarcelona, Catalonia, 08035, Spain
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University Hospital Virgen Macarena
RECRUITINGSeville, Andalusia, 41009, Spain
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University Hospital of Pisa
RECRUITINGPisa, 56124, Italy
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University Hospitals Leuven, Campus Gasthuisberg, Department of Infectious Diseases
RECRUITINGLeuven, 3000, Belgium
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University Medical Center "N. I. Pirogov", Burns and Plastic Surgery Clinic
RECRUITINGSofia, 1606, Bulgaria
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University Medical Center "N. I. Pirogov", Clinic of Purulent-Septic Surgery
RECRUITINGSofia, 1606, Bulgaria
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University Polyclinic Hospital of Modena
RECRUITINGModena, 41124, Italy
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University of Alabama at Birmingham School of Medicine, Department of Medicine
RECRUITINGBirmingham, Alabama, 35294-0006, United States
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University of Kentucky College of Medicine
RECRUITINGLexington, Kentucky, 40506, United States
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University of Michigan Health System (UMHS) - A. Alfred Taubman Health Care Center
RECRUITINGAnn Arbor, Michigan, 48109-5000, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27514, United States
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University of Pennsylvania School of Medicine
RECRUITINGPhiladelphia, Pennsylvania, 19104-6243, United States
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University of Pretoria / Steve Biko Academic Hospital
RECRUITINGPretoria, 0084, South Africa
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University of Texas Health Science Center at San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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Vajira Hospital
RECRUITINGBangkok, 10300, Thailand
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Victor Dupouy Hospital Center Argenteuil, Intensive Care Unit
RECRUITINGArgenteuil, 95107, France
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Washington University School of Medicine, Infectious Diseases Clinical Research Unit
RECRUITINGSt Louis, Missouri, 63110, United States
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Weill Cornell Medical College - NewYork-Presbyterian Hospital
RECRUITINGNew York, New York, 10065, United States
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Westmead Hospital
RECRUITINGSydney, New South Wales, 2145, Australia
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Wuxi People's Hospital
RECRUITINGWuxi, 214023, China
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Zhejiang Provincal Hospital of Chinese Medicine
RECRUITINGHangzhou, 310006, China
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Zhejiang Provincial People's Hospital
RECRUITINGHangzhou, 310014, China
Conditions
Explore the condition pages connected to this study.