New drug combo aims to halt blinding eye disease

NCT ID NCT07215390

Summary

This study is testing whether adding a new investigational drug called APL-3007 to an existing treatment (Syfovre) can better slow the progression of geographic atrophy, a late-stage form of age-related macular degeneration that causes permanent vision loss. About 240 participants aged 60+ who already receive Syfovre injections will receive either the new combination or continue with Syfovre plus a placebo. Researchers will measure changes in the size of the eye lesions and monitor safety over time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advanced Vision Research Institute

    RECRUITING

    Longmont, Colorado, 80503, United States

  • Associated Retina Consultants - Phoenix

    RECRUITING

    Phoenix, Arizona, 85020, United States

  • Austin Retina Associate (01046)

    RECRUITING

    San Marcos, Texas, 78666, United States

  • Austin Retina Associates

    RECRUITING

    Austin, Texas, 78705, United States

  • Austin Retina Associates - Round Rock (01032)

    RECRUITING

    Round Rock, Texas, 78681, United States

  • Barnet Dulaney Perkins Eye Center (01018)

    RECRUITING

    Mesa, Arizona, 85206, United States

  • Bay Area Retina Associates - Walnut Creek

    RECRUITING

    Walnut Creek, California, 94598, United States

  • California Retina Consultants (CRC) - Bakersfield Office

    RECRUITING

    Bakersfield, California, 93309, United States

  • Center for Retina and Macular Disease (01026)

    RECRUITING

    Winter Haven, Florida, 33880, United States

  • Charleston Neuroscience Institute LLC - Ladson

    RECRUITING

    Ladson, South Carolina, 29456, United States

  • Charleston Neuroscience Institute, LLC - Mount Pleasant (01051)

    RECRUITING

    Mt. Pleasant, South Carolina, 29464, United States

  • Colorado Retina Associates, PLLC

    RECRUITING

    Lakewood, Colorado, 80228, United States

  • Cumberland Valley Retina Consultants (CVRC)

    RECRUITING

    Hagerstown, Maryland, 21740, United States

  • EyeHealth Northwest

    RECRUITING

    Portland, Oregon, 97225, United States

  • Florida Retina Institute - Orlando (01053)

    RECRUITING

    Orlando, Florida, 32806, United States

  • Illinois Retina Associates, S.C. - Oak Park (01061)

    RECRUITING

    Oak Park, Illinois, 60304, United States

  • Long Island Vitreoretinal Consultants - Westbury

    RECRUITING

    Long Island City, New York, 11590, United States

  • Mid Atlantic Retina - Philadelphia (01017)

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • Mississippi Retina Associates

    RECRUITING

    Madison, Mississippi, 39110, United States

  • Orange County Retina Medical Group

    RECRUITING

    Santa Ana, California, 92705, United States

  • Retina Assocaites of Cleveland, Inc (01048)

    RECRUITING

    Cleveland, Ohio, 44122, United States

  • Retina Associates New Orleans - Jefferson Parish Location

    RECRUITING

    Metairie, Louisiana, 70001, United States

  • Retina Center of Texas - Southlake

    RECRUITING

    Southlake, Texas, 76092, United States

  • Retina Consultants P.C.

    RECRUITING

    Indianapolis, Indiana, 46214, United States

  • Retina Consultants San Diego

    RECRUITING

    Poway, California, 92064, United States

  • Retina Consultants of Orange County - Fullerton Office

    RECRUITING

    Fullerton, California, 93825, United States

  • Retina Consultants of Texas (01055)

    RECRUITING

    Schertz, Texas, 78154, United States

  • Retina Consultants of Texas - Abilene (01035)

    RECRUITING

    Abilene, Texas, 79606, United States

  • Retina Consultants of Texas - Bellaire (01067)

    RECRUITING

    Bellaire, Texas, 77401, United States

  • Retina Consultants of Texas - Katy

    RECRUITING

    Katy, Texas, 77494, United States

  • Retina Consultants of Texas - San Antonio Medical Center

    RECRUITING

    San Antonio, Texas, 78240, United States

  • Retina Consultants of Texas - The Woodlands

    RECRUITING

    The Woodlands, Texas, 73384, United States

  • Retina Specialty Institute - Pensacola

    RECRUITING

    Pensacola, Florida, 32503, United States

  • Retina Vitreous Associates of Florida (RVA) - Saint Petersburg

    RECRUITING

    St. Petersburg, Florida, 33711, United States

  • Retinal Research Institute, LLC (01021)

    RECRUITING

    Phoenix, Arizona, 85053, United States

  • Salehi Retina Institute, Inc dba Retina Associate or Southern California (01034)

    RECRUITING

    Huntington Beach, California, 92647, United States

  • Southeast Retina Center

    RECRUITING

    Augusta, Georgia, 30909, United States

  • Texas Retina Associates

    RECRUITING

    Dallas, Texas, 75231, United States

  • The Retina Partners - Encino

    RECRUITING

    Encino, California, 07003, United States

  • Tyler Retina Consultants

    RECRUITING

    Tyler, Texas, 75703, United States

  • University of Wisconsin Health - University Station Clinic

    RECRUITING

    Madison, Wisconsin, 53705, United States

  • Valley Retina Institute- McAllen (01076)

    RECRUITING

    McAllen, Texas, 78503, United States

  • Verum Research, LLC

    RECRUITING

    Eugene, Oregon, 97401, United States

Conditions

Explore the condition pages connected to this study.