New drug trial aims to tame severe eczema itch and rash

NCT ID NCT06881251

Summary

This study is testing an investigational drug called JNJ-95475939 to see if it can reduce the rash and severe itch of moderate to severe atopic dermatitis (eczema). It will involve about 256 adults whose eczema is not well controlled by standard creams or other treatments. Participants will receive either the new drug, a placebo (an inactive substance), or an existing approved drug for comparison over 24 weeks to measure improvements in skin and quality of life.

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Contacts and locations

Locations

  • Arlington Center for Dermatology

    Arlington, Texas, 76011, United States

  • BR TRIALS Ensaios Clinicos e Consultoria Ltda

    São Paulo, 01236030, Brazil

  • CIPREC

    Buenos Aires, C1061AAS, Argentina

  • Care Clinic

    Katowice, 40 568, Poland

  • Center for Clinical Studies

    Houston, Texas, 77004, United States

  • Centre De Recherche Dermatologique Du Quebec Metropolitain

    Québec, Quebec, G1V 4X7, Canada

  • Centrum Badan Klinicznych PI House sp z o o

    Gdansk, 80 546, Poland

  • Centrum Medyczne All Med

    Krakow, 30 033, Poland

  • Centrum Medyczne Angelius Provita

    Katowice, 40-611, Poland

  • Centrum Terapii Wspolczesnej J M Jasnorzewska Spolka Komandytowo Akcyjna

    Lodz, 90-338, Poland

  • Ceti - Centro de Estudos Em Terapias Inovadoras

    Curitiba, 80.030-110, Brazil

  • Charite - Universitaetsmedizin Berlin (CCM)

    Berlin, 10117, Germany

  • Dawes Fretzin Clinical Research Group LLC

    Indianapolis, Indiana, 46250, United States

  • DeNova Research

    Chicago, Illinois, 60602, United States

  • Derma Internacional S A

    Buenos Aires, C1426, Argentina

  • Dermatology Research Institute Inc

    Calgary, Alberta, T2J 7E1, Canada

  • Dr. Chih ho Hong Medical

    Surrey, British Columbia, V3R 6A7, Canada

  • Eurofins bioskin GmbH

    Hamburg, 20095, Germany

  • Fachklinik Bad Bentheim

    Bad Bentheim, 48455, Germany

  • First OC Dermatology

    Fountain Valley, California, 92708, United States

  • Frontier Derm Partners CRO, LLC

    Mill Creek, Washington, 98012, United States

  • Fukuoka University Hospital

    Fukuoka, 814-0180, Japan

  • Fundacao do ABC Centro Universitario FMABC

    Santo André, 09060 870, Brazil

  • Grupo Dermatologico Y Estetico Pedro Jaen

    Madrid, 28002, Spain

  • Guys and St Thomas NHS Foundation Trust

    London, SE1 9RT, United Kingdom

  • Hamilton Research LLC

    Alpharetta, Georgia, 30022, United States

  • Hosp. Clinico Univ. de Santiago

    Santiago de Compostela, 15706, Spain

  • Hosp. Gral. Univ. Dr. Balmis

    Alicante, 03010, Spain

  • Hosp. Univ. San Cecilio

    Granada, 18016, Spain

  • Hosp. Univ. de Bellvitge

    LHospitalet de Llobregat, 08907, Spain

  • Hosp. Univ. de La Princesa

    Madrid, 28006, Spain

  • Hosp. de Manises

    Manises, 46940, Spain

  • Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP

    Ribeirão Preto, 14048 900, Brazil

  • Hospital De Clinicas De Porto Alegre

    Porto Alegre, 90035 903, Brazil

  • INAER - Investigación en Alergias y Enfermedades Respiratorias

    Buenos Aires, C1425, Argentina

  • ISA - Interdisciplinary Study Association GmbH

    Berlin, 10789, Germany

  • Indiana Clinical Trial Center

    Plainfield, Indiana, 46168, United States

  • Innovaderm Research Inc.

    Montreal, Quebec, H2X 2V1, Canada

  • Instituto Brasil de Pesquisa Clinica

    Rio de Janeiro, 20241 180, Brazil

  • Instituto de Neumonologia y Dermatologia

    Buenos Aires, C1425, Argentina

  • Jitaikai Tachikawa dermatology clinic

    Tachikawa, 190 0023, Japan

  • Karma Clinical Trials Inc.

    St. John's, Newfoundland and Labrador, A1A 4Y3, Canada

  • Klinika Ambroziak Dermatologia

    Warsaw, 02 953, Poland

  • Kume Clinic

    Sakai, 593 8324, Japan

  • Lynderm Research Inc.

    Markham, Ontario, L3P 1X2, Canada

  • Medizinische Fakultaet Carl Gustav Carus Technische Universitaet Dresden

    Dresden, 01307, Germany

  • Mie University Hospital

    Tsu, 514-8507, Japan

  • Nomura Dermatology Clinic

    Yokohama, 221 0825, Japan

  • Northwick Park Hospital

    London, HA13UJ, United Kingdom

  • Optima Research

    Boardman, Ohio, 44512, United States

  • Oregon Medical Research Center

    Portland, Oregon, 97201, United States

  • Osaka Habikino Medical Center

    Habikino, 583 8588, Japan

  • Progressive Clinical Research

    San Antonio, Texas, 78213, United States

  • Queens Square Medical Facilities

    Yokohama, 220 6208, Japan

  • Red River Research Partners LLC

    Fargo, North Dakota, 58103, United States

  • Royal London Hospital

    London, E1 1BB, United Kingdom

  • Royalderm Agnieszka Nawrocka

    Warsaw, 02962, Poland

  • Salford Royal Hospital

    Salford, M6 8HD, United Kingdom

  • Sapporo Skin Clinic

    Sapporo, 060 0063, Japan

  • Shirasaki Dermatology Clinic

    Takaoka Shi, 933-0871, Japan

  • SimcoDerm Medical and Surgical Dermatology Centre

    Barrie, Ontario, L4M 7G1, Canada

  • Specjalistyczny gabinet dermatologiczny Aplikacyjno Badawczy Marek Brzewski Pawel Brzewski Spolka Cywilna

    Krakow, 30-002, Poland

  • Studienzentrum Dr Schwarz Germany

    Langenau, 89129, Germany

  • Studienzentrum an der Hase GbR

    Bramsche, 49565, Germany

  • Teikyo University Hospital

    Itabashi Ku, 173 8606, Japan

  • The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust

    Kings Lynn, PE30 4ET, United Kingdom

  • Therapia Nova

    Warsaw, 01 595, Poland

  • Universitatsklinikum Dusseldorf

    Düsseldorf, 40225, Germany

  • Universitatsklinikum Frankfurt

    Frankfurt, 60596, Germany

  • University of California Los Angeles - Division of Dermatology

    Los Angeles, California, 90024, United States

  • WroMedica I Bielicka A Strzalkowska s c

    Wroclaw, 51 685, Poland

Conditions

Explore the condition pages connected to this study.