New hope for rare blood cancer: platform trial tests multiple drugs at once
NCT ID NCT07018752
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing three oral drugs—roginolisib, golcadomide, and azacitidine—alone or in combination for people with peripheral T-cell lymphoma that has come back or not responded to treatment. The trial has two phases: Phase 1 finds safe doses, and Phase 2 checks if the drugs improve outcomes. About 49 adults will take part, with the goal of gathering early data to design larger future studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
roginolisib, golcadomide, and azacitidine (oral drugs)
What this could lead to
If successful, this trial could identify new drug combinations that improve outcomes for people with hard-to-treat peripheral T-cell lymphoma.
What could go wrong
This is an early-phase trial with only 49 participants, so results may not apply to all patients. The drugs may cause side effects or fail to work better than existing options.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CH de la Côte Basque - Service Hématologie
RECRUITINGSaint-Jean-de-Luz, 64500, France
Contact
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CH du Mans - Centre de Cancérologie de la Sarthe - Service Hématologie
NOT_YET_RECRUITINGLe Mans, 72000, France
Contact
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CHRU Nancy - Hôpital Brabois - Service Hématologie
NOT_YET_RECRUITINGVandœuvre-lès-Nancy, 54500, France
Contact
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CHU Dijon Bourgogne - Service Hématologie Clinique
RECRUITINGDijon, 21000, France
Contact
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CHU Estaing - Service Thérapie Cellulaire et Hématologie Clinique
NOT_YET_RECRUITINGClermont-Ferrand, 63100, France
Contact
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CHU Lyon-Sud - Hématologie Clinique
RECRUITINGPierre-Bénite, 69310, France
Contact
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CHU Pontchaillou - Hématologie Clinique
NOT_YET_RECRUITINGRennes, 35000, France
Contact
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CHU de Bordeaux - Hôpital Haut-Lévêque - Centre François Magendie - Service d'Hématologie et Thérapie Cellulaire
NOT_YET_RECRUITINGPessac, 33600, France
Contact
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CHU de Grenoble - Service Hématologie
NOT_YET_RECRUITINGLa Tronche, 38700, France
Contact
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CHU de Lille - Hôpital Claude Huriez - Service des Maladies du Sang
RECRUITINGLille, 59000, France
Contact
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CHU de Montpellier - Département d'Hématologie Clinique
RECRUITINGMontpellier, 34080, France
Contact
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CHU de Nantes - Service Hématologie
RECRUITINGNantes, 44000, France
Contact
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CHU de Poitiers - Hôpital de la Milétrie - Service d'Oncologie Hématologique et Thérapie Cellulaire
RECRUITINGPoitiers, 86000, France
Contact
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Centre Henri Becquerel - Service Hématologie
RECRUITINGRouen, 76000, France
Contact
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Hôpital Henri Mondor - Unité Hémopathies Lymphoïdes
RECRUITINGCréteil, 94000, France
Contact
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Hôpital Necker - Service Hématologie Adultes
RECRUITINGParis, 75015, France
Contact
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Institut Paoli Calmettes - Service Hématologie
NOT_YET_RECRUITINGMarseille, 13009, France
Contact
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Institut d'Hématologie de Basse Normandie - Service Hématologie (CHU Hôpital Côte de Nacre)
RECRUITINGCaen, 14000, France
Contact
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Institut de Cancérologie Strasbourg Europe - Service Hématologie
RECRUITINGStrasbourg, 67200, France
Contact
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Institut de Cancérologie et d'Hématologie Universitaire de Saint-Étienne - Service Hématologie
RECRUITINGSaint-Etienne, 42000, France
Contact