New hope for tough bladder cancers: drug combo trial launches

NCT ID NCT05562830

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 26 times

Summary

This study is for people with advanced bladder cancer that has stopped responding to standard immunotherapy. It tests new drug combinations, with or without the drug pembrolizumab, to see if they can shrink tumors or slow the disease. About 48 adults will take part, and the main goals are to check safety and how well the tumors respond.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anschutz Cancer Pavilion ( Site 1017)

    COMPLETED

    Aurora, Colorado, 80045, United States

  • Asan Medical Center ( Site 1901)

    RECRUITING

    Seoul, 05505, South Korea

    Contact Phone: •••-•••-••••

  • Bradford Hill ( Site 1155)

    RECRUITING

    Santiago, Region M. de Santiago, 8420383, Chile

    Contact Phone: •••-•••-••••

  • Cleveland Clinic-Taussig Cancer Center ( Site 1036)

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-••••

  • FALP-UIDO ( Site 1151)

    RECRUITING

    Santiago, Region M. de Santiago, 7500921, Chile

    Contact Phone: •••-•••-••••

  • Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1408)

    RECRUITING

    Milan, Lombardy, 20133, Italy

    Contact Phone: •••-•••-••••

  • Hospital Clinico San Carlos ( Site 1765)

    RECRUITING

    Madrid, 28040, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitari Vall d'Hebron ( Site 1767)

    RECRUITING

    Barcelona, Catalonia, 08035, Spain

    Contact Phone: •••-•••-••••

  • Huntsman Cancer Institute ( Site 1041)

    RECRUITING

    Salt Lake City, Utah, 84112-5500, United States

    Contact Phone: •••-•••-••••

  • Indiana University Melvin and Bren Simon Cancer Center ( Site 1011)

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-••••

  • Istituto Nazionale Tumori IRCCS Fondazione Pascale-S.C. Sperimentazioni Cliniche ( Site 1406)

    RECRUITING

    Naples, 80131, Italy

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center ( Site 1031)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)-medical oncology ( Site 1302)

    RECRUITING

    Amsterdam, North Holland, 1066 CX, Netherlands

    Contact Phone: •••-•••-••••

  • Princess Margaret Cancer Centre ( Site 1106)

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-••••

  • ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 1201)

    RECRUITING

    London, London, City of, SW3 6JJ, United Kingdom

    Contact Phone: •••-•••-••••

  • Rabin Medical Center-Oncology ( Site 1504)

    RECRUITING

    Petah Tikva, 4941492, Israel

    Contact Phone: •••-•••-••••

  • Rambam Health Care Campus-Oncology ( Site 1501)

    RECRUITING

    Haifa, 3109601, Israel

    Contact Phone: •••-•••-••••

  • Rigshospitalet-Dept. of Oncology ( Site 1701)

    RECRUITING

    Copenhagen, Capital Region, 2100, Denmark

    Contact Phone: •••-•••-••••

  • Royal Brisbane and Women's Hospital-Medical Oncology Clinical Trials Unit, Cancer Care Services ( Site 1952)

    COMPLETED

    Brisbane, Queensland, 4029, Australia

  • Samsung Medical Center ( Site 1902)

    RECRUITING

    Seoul, 06351, South Korea

    Contact Phone: •••-•••-••••

  • Severance Hospital, Yonsei University Health System ( Site 1903)

    RECRUITING

    Seoul, 03722, South Korea

    Contact Phone: •••-•••-••••

  • Sheba Medical Center-ONCOLOGY ( Site 1503)

    RECRUITING

    Ramat Gan, 5265601, Israel

    Contact Phone: •••-•••-••••

  • Siteman Cancer Center ( Site 1038)

    RECRUITING

    St Louis, Missouri, 63108, United States

    Contact Phone: •••-•••-••••

  • St Bartholomew's Hospital ( Site 1206)

    RECRUITING

    London, London, City of, EC1A 7BE, United Kingdom

    Contact Phone: •••-•••-••••

  • UPMC Hillman Cancer Center ( Site 1014)

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-••••

  • University of California San Francisco ( Site 1044)

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-••••

  • University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 1045)

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-••••

  • University of Chicago Medical Center ( Site 1037)

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.