New hope for Tough-to-Treat bile duct cancer
NCT ID NCT05874414
Summary
This study is testing whether a new drug called GNS561 works better when combined with an existing drug, trametinib, for people with advanced bile duct cancer that has a specific genetic change (KRAS mutation) and has stopped responding to standard chemotherapy. The main goals are to find a safe dose and see if the combination can shrink tumors. It is for adults whose cancer has progressed after one or two prior treatments.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Froedtert Hospital and the Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Hospital of the University of Pennsylvania
TERMINATEDPhiladelphia, Pennsylvania, 19104, United States
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LA Cancer Network
RECRUITINGLos Angeles, California, 92801, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Orlando Health
RECRUITINGOrlando, Florida, 32806, United States
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Pan American Center for Oncology Trials, LLC
RECRUITINGRio Piedras, Puerto Rico, 00935, Puerto Rico
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Roswell Park Cancer Institute
TERMINATEDBuffalo, New York, 14263, United States
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USC Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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University Of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Texas, MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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University of Virginia Comprehensive Cancer Center
RECRUITINGCharlottesville, Virginia, 22908, United States
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Conditions
Explore the condition pages connected to this study.