New Two-Drug combo could supercharge deworming in african kids

NCT ID NCT06282315

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This large Phase 3 trial in Ghana and Kenya will test whether a single dose of a new albendazole-ivermectin combination pill works better than the standard albendazole alone to prevent soil-transmitted worm infections in 20,000 school-aged children. The study focuses on safety and how well the combo reduces worm infections. If it works, it could improve mass deworming programs across Africa.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

albendazole and ivermectin combination tablet

What this could lead to

If successful, this could provide a more effective single-dose treatment to prevent worm infections in millions of children, reducing disease spread.

What could go wrong

This is a large trial, but the new combination may cause more side effects than the standard drug, and results may vary by region or worm type.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

helminthiasis Hookworm Infections

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ghana Health Service (GHS)

    RECRUITING

    Accra, Accra, Ghana

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Kenya Medical Research Institution (KEMRI)

    RECRUITING

    Nairobi, Nairobi County, 00200, Kenya

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••