New Two-Drug combo could supercharge deworming in african kids
NCT ID NCT06282315
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This large Phase 3 trial in Ghana and Kenya will test whether a single dose of a new albendazole-ivermectin combination pill works better than the standard albendazole alone to prevent soil-transmitted worm infections in 20,000 school-aged children. The study focuses on safety and how well the combo reduces worm infections. If it works, it could improve mass deworming programs across Africa.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- albendazole and ivermectin combination tablet
- What this could lead to
- If successful, this could provide a more effective single-dose treatment to prevent worm infections in millions of children, reducing disease spread.
- What could go wrong
- This is a large trial, but the new combination may cause more side effects than the standard drug, and results may vary by region or worm type.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ghana Health Service (GHS)
RECRUITINGAccra, Accra, Ghana
-
Kenya Medical Research Institution (KEMRI)
RECRUITINGNairobi, Nairobi County, 00200, Kenya