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New hope for devastating Women's cancers: experimental combo therapy enters major trial

NCT ID NCT03651206

Recruiting now Disease control Sponsor: ARCAGY/ GINECO GROUP Source: ClinicalTrials.gov ↗

Summary

This international study is testing whether combining two newer drugs (dostarlimab and niraparib) works better than using niraparib alone or standard chemotherapy for women with rare, aggressive uterine or ovarian carcinosarcoma that has returned after initial treatment. The trial aims to find more effective options for these difficult-to-treat cancers where current treatments offer limited benefit. Researchers will measure how well tumors shrink and how long patients live on these different approaches.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliera Ordine Mauriziano Di Torino

    ACTIVE_NOT_RECRUITING

    Torino, 10128, Italy

  • Azienda Ospedaliera Per L'Emergenza Cannizzaro

    ACTIVE_NOT_RECRUITING

    Catania, 95126, Italy

  • Azienda Ospedaliero-Universitaria di Bologna IRCCS Istituto di Ricerca e di Cura a Carattere Scientifico

    ACTIVE_NOT_RECRUITING

    Bologna, 40138, Italy

  • CHRU Jean Minjoz

    ACTIVE_NOT_RECRUITING

    Besançon, 25000, France

  • CHU Saint-Etienne - Pôle de Cancérologie

    NOT_YET_RECRUITING

    Saint-Priest-en-Jarez, 42271, France

    Contact

  • CHU de BREST - Hôpital Cavale Blanche

    NOT_YET_RECRUITING

    Brest, 29200, France

    Contact

  • CHU de Limoges - Hôpital Dupuytren

    NOT_YET_RECRUITING

    Limoges, 87042, France

    Contact

  • Centre Eugène Marquis

    RECRUITING

    Rennes, 35000, France

    Contact

  • Centre François Baclesse

    RECRUITING

    Caen, 14000, France

    Contact

  • Centre Georges François Leclerc

    NOT_YET_RECRUITING

    Dijon, 21079, France

    Contact

  • Centre Hospitalier Universitaire de Nîmes, Institut de Cancérologie du GARD

    NOT_YET_RECRUITING

    Nîmes, 30900, France

    Contact

  • Centre Jean Perrin

    RECRUITING

    Clermont-Ferrand, 63000, France

    Contact

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69001, France

    Contact

  • Centre Oscar Lambret

    RECRUITING

    Lille, 59000, France

    Contact

  • Centre Régional de Lutte contre le cancer - Institut Bergonié

    ACTIVE_NOT_RECRUITING

    Bordeaux, 33000, France

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    ACTIVE_NOT_RECRUITING

    Roma, 00168, Italy

  • Groupe Hospitalier des Diaconesses Croix Saint-Simon

    RECRUITING

    Paris, 75020, France

    Contact

  • Hopital Milétrie - Centre Hospitalier Universitaire Poitiers

    RECRUITING

    Poitiers, 86000, France

    Contact

    Contact

  • Hospital Clinico Universitario De Valencia

    ACTIVE_NOT_RECRUITING

    Valencia, 46010, Spain

  • Hospital Universitario 12 De Octubre

    ACTIVE_NOT_RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Ramon Y Cajal

    ACTIVE_NOT_RECRUITING

    Madrid, 28034, Spain

  • Hospital Virgen de la Arrixaca

    ACTIVE_NOT_RECRUITING

    Murcia, 30120, Spain

  • Humanitas Mirasole S.p.A.

    ACTIVE_NOT_RECRUITING

    Milan, 20159, Italy

  • Hôpital Privé du Confluent S.A.S.

    ACTIVE_NOT_RECRUITING

    Nantes, 44000, France

  • Hôpitaux Universitaires de Strasbourg

    ACTIVE_NOT_RECRUITING

    Strasbourg, France

  • ICANS

    RECRUITING

    Strasbourg, 67200, France

    Contact

  • ICL - Centre Alexis Vautrin

    NOT_YET_RECRUITING

    Vandœuvre-lès-Nancy, 54519, France

    Contact

  • ICO - Centre René Gauducheau

    RECRUITING

    Saint-Herblain, 44800, France

    Contact

  • ICO Paul Papin

    NOT_YET_RECRUITING

    Angers, 49055, France

    Contact

  • IRCCS Istituto Nazionale Tumori Fondazione Pascale

    ACTIVE_NOT_RECRUITING

    Naples, 80131, Italy

  • IUCT Oncopole - Institut Claudius Régaud

    RECRUITING

    Toulouse, 31000, France

    Contact

  • Institut Curie

    RECRUITING

    Paris, 76016, France

    Contact

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

    Contact

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, 13000, France

    Contact

  • Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l.

    ACTIVE_NOT_RECRUITING

    Meldola, 47014, Italy

  • Ospedale San Raffaele S.r.l.

    ACTIVE_NOT_RECRUITING

    Milan, 20132, Italy

Conditions

Explore the condition pages connected to this study.

ENDOMETRIAL CARCINOSARCOMA OVARIAN CARCINOSARCOMA