New hope for hard-to-treat colorectal cancer: triple therapy enters phase 2 trial

NCT ID NCT06589440

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new oral drug (SR-8541A) combined with two immunotherapy drugs for people with a tough-to-treat type of colorectal cancer (MSS-CRC) that has spread and stopped responding to standard treatments. The goal is to find the best dose and see if the combination is safe and shrinks tumors. About 70 adults with or without liver metastases will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atlantic Health

    RECRUITING

    Morristown, New Jersey, 07960, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Swedish

    RECRUITING

    Seattle, Washington, 98104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Oncology- Austin

    RECRUITING

    Austin, Texas, 78745, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Oncology- Northeast Texas

    RECRUITING

    Tyler, Texas, 75702, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Oncology- Sammons- DFW

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Texas M.D. Anderson Cancer Center GI Medical Oncology Dept

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••