Could a double-drug punch shrink head and neck tumors before radiation?

NCT ID NCT06959108

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 32 times

Summary

This study tests whether adding an immunotherapy drug (pucotenlimab) to a targeted therapy (MRG003) before standard chemoradiation can shrink tumors more effectively than MRG003 alone in people with advanced head and neck cancer. About 106 adults aged 18–75 will take part. The goal is to see if the combination improves response rates and delays cancer progression.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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