Novartis tests new weapon against silent parasite disease

NCT ID NCT06632600

Summary

This study is testing whether a new drug called LXE408 can clear or reduce the parasite that causes chronic Chagas disease. The trial will involve 130 adults with the disease but without severe organ damage. Researchers will compare LXE408 against a placebo and the current standard treatment, benznidazole, to see which works better at eliminating the parasite from the blood.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030-3411, United States

    Contact

    Contact Email: •••••@•••••

  • Boston Medical Center

    RECRUITING

    Boston, Massachusetts, 02118, United States

    Contact

    Contact Email: •••••@•••••

  • Novartis Investigative Site

    RECRUITING

    CABA, Buenos Aires, 1407, Argentina

  • Novartis Investigative Site

    RECRUITING

    CABA, Buenos Aires, C1221ADC, Argentina

  • Novartis Investigative Site

    RECRUITING

    Corrientes, W3400CDS, Argentina

  • Novartis Investigative Site

    RECRUITING

    Córdoba, X5016KEH, Argentina

  • Novartis Investigative Site

    RECRUITING

    Formosa, P3600KGC, Argentina

  • Novartis Investigative Site

    RECRUITING

    Montes Claros, Minas Gerais, 39401-001, Brazil

  • Novartis Investigative Site

    RECRUITING

    Recife, Pernambuco, 50100-060, Brazil

  • Novartis Investigative Site

    RECRUITING

    Rio de Janeiro, Rio de Janeiro, 21040-360, Brazil

  • Novartis Investigative Site

    RECRUITING

    São Caetano do Sul, São Paulo, 09521-160, Brazil

  • Novartis Investigative Site

    RECRUITING

    Barranquilla, Atlántico, 080005, Colombia

  • Novartis Investigative Site

    RECRUITING

    Yopal, Casanare Department, 850009, Colombia

  • Novartis Investigative Site

    RECRUITING

    Bogotá, 110131, Colombia

  • Novartis Investigative Site

    RECRUITING

    Bogotá, 111411, Colombia

  • Novartis Investigative Site

    RECRUITING

    Floridablanca, 681017, Colombia

  • Novartis Investigative Site

    RECRUITING

    San Gil, 684031, Colombia

  • Olive View UCLA Educ and Res Ins

    RECRUITING

    Sylmar, California, 91342, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Florida Shands

    RECRUITING

    Gainesville, Florida, 32610-0486, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.