Engineered immune cells take aim at Tough-to-Treat blood cancer

NCT ID NCT06420089

Summary

This first-in-human study is testing a new type of CAR-T cell therapy called Senza5 CART5 for patients with aggressive T-cell lymphoma that has returned or resisted standard treatments. Researchers will give 30 participants a single infusion of these specially modified immune cells to find the safest and most effective dose. The main goal is to determine if this approach is safe and well-tolerated while also looking for early signs that it might help control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Pennsylvania - Abramson Caner Center

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.