Experimental pill targets Cancer's 'Guardian Gene' mutation

NCT ID NCT06386146

Summary

This clinical trial is testing an experimental oral medication called JAB-30355 for adults with advanced solid tumors that have a specific genetic mutation called TP53 Y220C. The study aims to determine the safest dose and see if the drug can shrink tumors in patients who have already tried at least one other treatment. Researchers will enroll 144 participants to evaluate both safety and early signs of effectiveness.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Denver, Colorado, 80218, United States

  • Research Site

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Research Site

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

  • Research Site

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

  • Research Site

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

  • Research Site

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510000, China

  • Research Site

    NOT_YET_RECRUITING

    Jinan, Shandong, 250117, China

  • Research Site

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

  • Research site

    RECRUITING

    Lake Mary, Florida, 32771, United States

  • Research site

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Research site

    TERMINATED

    Canton, Ohio, 44718, United States

  • Research site

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Research site

    RECRUITING

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.