New 'Smart Bomb' drug targets tough cancers in major trial

NCT ID NCT06747585

Summary

This study is testing a new experimental drug called ALE.P02 for adults with advanced squamous cell cancers that have spread or can't be removed by surgery. The drug is designed to target cancer cells that have a specific marker called Claudin-1. Researchers will first find the safest and most effective dose, then see how well the drug works to shrink tumors in patients with cancers of the lung, head and neck, cervix, or esophagus who have already tried standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AP-HM Hôpital de La Timone CEPCM

    RECRUITING

    Marseille, 13005, France

  • Buddihist Tzu Chi Medical Foundation - Taipei Tzu Chi Hospital

    RECRUITING

    Taipei, 231020, Taiwan

  • CHRU De Lille- Hôpital Claude Huriez - Medical Oncology

    RECRUITING

    Lille, 59000, France

  • Centre Georges Francois Leclerc - Oncologie Medicale

    RECRUITING

    Dijon, 21079, France

  • Centre Hospitalier Universitaire (CHU) de Toulouse - IUCT Oncopole

    RECRUITING

    Toulouse, 31100, France

  • Centro Ricerche Cliniche Verona

    RECRUITING

    Verona, Italy

  • Changhua Christian Medical Foundation Changhua Christian Hospital

    RECRUITING

    Changhua, 50006, Taiwan

  • Changhua Christian Medical Foundation Changhua Christian Hospital

    RECRUITING

    Changhua, 500209, Taiwan

  • Chinese University of Hong Kong - Prince of Wales Hospital

    RECRUITING

    Shatin, N.T., Hong Kong

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Hospital Universitari Vall D Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Quironsalud Madrid

    RECRUITING

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Hospital Universitario Virgen De La Macarena

    RECRUITING

    Seville, 41009, Spain

  • Hospital Universitario Virgen De La Victoria

    RECRUITING

    Málaga, 29010, Spain

  • Hospital Universitario Y Politécnico La Fe

    RECRUITING

    Valencia, 46026, Spain

  • IEO - Istituto Europeo di Oncologia, IRCCS

    RECRUITING

    Milan, 20141, Italy

  • Institut Bergonie

    RECRUITING

    Bordeaux, 33000, France

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

  • Mayo Foundation for Medical Education and Research - Mayo Cl

    RECRUITING

    Scottsdale, Arizona, 85259, United States

  • NEXT Oncology Barcelona

    RECRUITING

    Barcelona, 08023, Spain

  • NEXT Oncology Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • National Cancer Center

    RECRUITING

    Goyang-si, 10408, South Korea

  • National Cancer Centre Singapore

    RECRUITING

    Singapore, South West, 168583, Singapore

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100225, Taiwan

  • National University Cancer Institue

    RECRUITING

    Singapore, South West, 11907, Singapore

  • Norton Cancer Institue Downtown

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • Ospedale San Raffaele, IRCCS

    RECRUITING

    Milan, 20132, Italy

  • Ospedale Santa Maria delle Croci di Ravenna Oncologia

    RECRUITING

    Ravenna, 48121, Italy

  • PU A. Gemelli, Universita Cattolica del Sacro Cuore

    RECRUITING

    Roma, Italy

  • Providence Medical Foundation

    RECRUITING

    Fullerton, California, 92835, United States

  • START Hospital HM Nou Delfos

    RECRUITING

    Barcelona, Spain

  • START Madrid- Centro Integral Oncologico Clara Campal

    RECRUITING

    PAU de Sanchinarro, Madrid, 28050, Spain

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • The University of Chicago Medical Center - Oncology

    RECRUITING

    Chicago, Illinois, 60637, United States

  • USC Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

  • Yale Comprehensive Cancer Center

    RECRUITING

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.