First patients to receive experimental drug targeting common cancer mutation

NCT ID NCT06797336

Summary

This is the first human study of an experimental drug called PT0253 for people with advanced solid tumors that have a specific genetic change called KRAS G12D. The main goal is to find the safest dose and see how well the drug is tolerated in 115 participants. Researchers will also check if the drug shows any early signs of helping shrink tumors.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana Farber/Massachusetts General Hospital, Inc

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • New Experimental Therapeutics of San Antonio LLC

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • SCRI Lake Mary

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • START - South Texas Accelerated Research Therapeutics, LLC

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • START Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.