New pill targets Cancer's DNA repair in advanced tumor trial

NCT ID NCT05898399

Summary

This study is testing a new oral drug called ART6043 for people with advanced or metastatic solid tumors. It will check the safety and early signs of effectiveness of ART6043 when taken by itself and when combined with an existing cancer drug, olaparib. The trial will enroll about 220 participants, focusing on patients whose cancers have specific genetic weaknesses in DNA repair.

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Contacts and locations

Locations

  • Jefferson University Hospitals - Kimmel Cancer Center

    Philadelphia, Pennsylvania, 17107, United States

  • Mary Crowley Cancer Center - Clinic

    Dallas, Texas, 75251, United States

  • Memorial Sloan-Kettering Cancer Center (MSKCC)

    New York, New York, 10065-6800, United States

  • SCRI oncology partners

    Nashville, Tennessee, 37203, United States

  • South Texas Accelerated Research Therapeutics (START) - Midwest

    Grand Rapids, Michigan, 49546, United States

  • Stephenson Cancer Center - Oncology

    Oklahoma City, Oklahoma, 73104, United States

  • The University of Texas - MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.