First patients dosed in early trial of new pill targeting tough cancers
NCT ID NCT05627063
Summary
This is the first study in people to test a new oral drug called ABSK121-NX. The main goal is to find a safe dose and see how the body processes the drug in 169 patients with advanced solid tumors that have stopped responding to standard treatments. Researchers will also look for early signs that the drug might help control the cancer, especially in tumors with specific genetic changes in the FGFR genes.
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Contacts and locations
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Locations
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Chongqing University Cancer Hospital
Chongqing, Chongqing Municipality, China
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Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, 89119, United States
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Fujian Cancer Hospital (Department of Hepatobiliary and Pancreatic Oncology /Phase I Ward)
Fuzhou, China
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Gabrail Cancer Center Research
Canton, Ohio, 44718, United States
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Harbin Medical University Cancer Hospital (Gastroenterology Department 2nd Ward)
Haerbin, China
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Hubei Cancer Hospital
Wuhan, Hubei, China
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Hunan Central Hospital
Changsha, Hunan, China
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Jilin Cancer Hospital
Changchun, Jilin, China
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Liaoning Cancer Hospital (Phase I Ward)
Shenyang, China
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Mianyang Central Hospital
Mianyang, Sichuan, China
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Shanghai East Hospital Tongji University
Shanghai, Shanghai Municipality, China
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Shanxi Provincial Cancer Hospital
Taiyuan, Shanxi, China
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The Affiliated Hospital of Inner Mongolia Medical University
Hohhot, Inner Mongolia, China
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The First Affiliated Hospital of Henan University of Science & Technology
Luoyang, Henan, China
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The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
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The First Hospital of China Medical University
Shenyang, Liaoning, China
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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West China School of Medicine/West China Hospital of Sichuan University
Chengdu, Sichuan, China
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Yantai Yuhuangding Hospital (Department of Medical Oncology, 1)
Yantai, China
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Zhejiang University Cancer Hospital
Hangzhou, Zhejiang, China
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Zhongshan Hospital of Fudan University (Hepatological Surgery Department)
Shanghai, China
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Zhongshan Hospital of Fudan University (Medical Oncology Department)
Shanghai, China
Conditions
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