New cancer drug injected directly into tumors in first human trial

NCT ID NCT05155332

Summary

This is a first-in-human study testing a new drug called BI 1831169 for adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find the highest safe dose of the drug when given alone and when combined with an existing immunotherapy, and to see if the treatment can shrink tumors. The drug is given either as an injection directly into a tumor, an infusion into a vein, or both, and participants are closely monitored for safety and response.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ASST Grande Ospedale Metropolitano Niguarda

    NOT_YET_RECRUITING

    Milan, 20162, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliera Universitaria Integrata Verona

    NOT_YET_RECRUITING

    Verona, 37126, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Banner MD Anderson Cancer Center-Gilbert-55251

    RECRUITING

    Gilbert, Arizona, 85234, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CTR Eugène Marquis

    RECRUITING

    Rennes, 35042, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Charité - Universitätsmedizin Berlin

    NOT_YET_RECRUITING

    Berlin, 12203, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clínica Universidad de Navarra

    RECRUITING

    Pamplona, 31008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Edegem - UNIV UZ Antwerpen

    RECRUITING

    Edegem, 2650, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fundación Jiménez Díaz

    RECRUITING

    Madrid, 28040, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOP Timone

    RECRUITING

    Marseille, 13385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Duran i Reynals

    RECRUITING

    L'Hospitalet de Llobregat, 08907, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Quiron. I.C.U.

    NOT_YET_RECRUITING

    Barcelona, 08023, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • INS Bergonie

    RECRUITING

    Bordeaux, 33000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto Valenciano de Oncología

    NOT_YET_RECRUITING

    Valencia, 46009, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Istituto Di Candiolo

    NOT_YET_RECRUITING

    Candiolo (TO), 10060, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • M Health Fairview University of Minnesota Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of Innsbruck

    RECRUITING

    Innsbruck, 6020, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Morristown Medical Center

    RECRUITING

    Morristown, New Jersey, 07960, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orlando Health Cancer Institute

    RECRUITING

    Orlando, Florida, 32806, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peninsula Haematology & Oncology

    NOT_YET_RECRUITING

    Frankston, Victoria, 3199, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Prisma Health

    NOT_YET_RECRUITING

    Greenville, South Carolina, 29605, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Providence St. John's Health Center

    RECRUITING

    Santa Monica, California, 90404, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Salzburg Cancer Research Institute

    COMPLETED

    Salzburg, 5020, Austria

  • Southern Oncology Clinical Research Unit

    NOT_YET_RECRUITING

    Bedford Park, South Australia, 5062, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Leuven

    RECRUITING

    Leuven, 3000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitair Ziekenhuis Gent

    NOT_YET_RECRUITING

    Ghent, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Bern

    NOT_YET_RECRUITING

    Bern, 3010, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Geneva

    NOT_YET_RECRUITING

    Geneva, 1205, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Arizona

    RECRUITING

    Tucson, Arizona, 85719, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California San Diego

    NOT_YET_RECRUITING

    La Jolla, California, 92037, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado Denver

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Louisville

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Miami

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Heidelberg

    NOT_YET_RECRUITING

    Heidelberg, 69120, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Tübingen

    RECRUITING

    Tübingen, 72076, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Ulm

    RECRUITING

    Ulm, 89081, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Winship Cancer Institute

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.