Scientists test new drug cocktail to fight advanced colon and pancreatic cancers

NCT ID NCT05039177

Summary

This early-stage trial tested a new oral drug, ERAS-007, in combination with other cancer therapies for people with advanced colorectal or pancreatic cancer. The main goals were to find the safest and most effective dose and to see if the drug combinations could shrink tumors. The study involved 101 adults whose cancers had specific genetic mutations and had spread to other parts of the body.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Duke Cancer Institute

    Durham, North Carolina, 27710, United States

  • Henry Ford Cancer Institute

    Detroit, Michigan, 48202, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02215, United States

  • Sarah Cannon Research Institute (Tennessee Oncology)

    Nashville, Tennessee, 37203, United States

  • Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UCSF Mount Zion Medical Ctr

    San Francisco, California, 94158, United States

  • University of Alabama at Birmingham (O'Neal Comprehensive Cancer Center)

    Birmingham, Alabama, 35233, United States

  • University of California Irvine College of Medicine

    Orange, California, 92868, United States

  • University of Washington - Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

  • Washington University (Siteman Cancer Center)

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.