Radioactive 'Trojan Horse' drug enters brain cancer battle

NCT ID NCT05739942

Summary

This early-stage study is testing a new radioactive drug called [177Lu]Lu-NeoB for glioblastoma, a very aggressive brain cancer. For newly diagnosed patients, the drug is added to standard radiation and chemotherapy. For patients whose cancer has returned, it's given alone. The main goals are to find the safest and most effective dose and see how well the body tolerates it.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Mayo Clinic Jacksonville

    Jacksonville, Florida, 32224, United States

  • Memorial Sloan Kettering Cancer Ctr

    New York, New York, 10065, United States

  • Novartis Investigative Site

    Dijon, Cote D Or, 21034, France

  • Novartis Investigative Site

    Marseille, 13885, France

  • Novartis Investigative Site

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Novartis Investigative Site

    Essen, 45147, Germany

  • Novartis Investigative Site

    München, 80377, Germany

  • Novartis Investigative Site

    Rostock, 18057, Germany

  • Novartis Investigative Site

    Jerusalem, 9112001, Israel

  • Novartis Investigative Site

    Reggio Emilia, RE, 42123, Italy

  • Novartis Investigative Site

    Porto, 4200-072, Portugal

  • Novartis Investigative Site

    Granada, Andalusia, 18014, Spain

  • Novartis Investigative Site

    Badalona, Catalonia, 08916, Spain

  • Novartis Investigative Site

    Barcelona, Catalonia, 08003, Spain

  • Novartis Investigative Site

    Barcelona, 08907, Spain

  • Novartis Investigative Site

    Madrid, 28009, Spain

  • Novartis Investigative Site

    Madrid, 28040, Spain

  • Novartis Investigative Site

    Liverpool, CH63 4JY, United Kingdom

  • Uni of Utah Huntsman Cancer Inst

    Salt Lake City, Utah, 84103, United States

  • Univ Hosp Cleveland Medical Center

    Cleveland, Ohio, 44106-5028, United States

  • University of California LA

    Los Angeles, California, 90095, United States

  • University of Colorado Denver

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.