New pill targets stubborn high blood pressure when standard meds fail

NCT ID NCT05769608

Completed Disease control Sponsor: Mineralys Therapeutics Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether a new drug called lorundrostat could help lower blood pressure in people whose high blood pressure wasn't controlled by their current medications. 285 adults with uncontrolled hypertension took either the new drug or a placebo pill in addition to a standard set of blood pressure medicines for 12 weeks. Researchers measured blood pressure changes to see if the new add-on treatment was safe and effective.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

ACRC Trials

Plano, Texas, 75024, United States
AMS Cardiology

Horsham, Pennsylvania, 19044, United States
Accel Research Sites

Decatur, Georgia, 30030, United States
Accelerated Enrollment Solutions (AES)- Anderson

Anderson, South Carolina, 29621, United States
Accelerated Enrollment Solutions (AES)- Vista

Vista, California, 92083, United States
ActivMed Practices & Research, LLC

Methuen, Massachusetts, 01844, United States
Advanced Internal Medicine, PLLC (Elligo Health Research)

Paducah, Kentucky, 42001, United States
Albany Medical College Div of Community Endocrinology

Albany, New York, 12203, United States
Alta Pharmaceutical Research Center

Peachtree Corners, Georgia, 30092, United States
Asheville Clinical Trials (Elite Clinical Network)

Asheville, North Carolina, 28803, United States
Blue Coast Research Center

Vista, California, 92081, United States
Boston Clinical Trials

Boston, Massachusetts, 02131, United States
Brown Road Family Medicine

Mesa, Arizona, 85213, United States
Burke Internal Medicine

Burke, Virginia, 22015, United States
CMR of Greater New Haven

Hamden, Connecticut, 06517, United States
Cambridge Clinical Trials

Alexandria, Louisiana, 71301, United States
Cardiology, P.C. - Birmingham

Birmingham, Alabama, 35211, United States
Catalina Research Institute

Montclair, California, 91763, United States
Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Centricity Research (Aventiv Research) - Women's Health

Dublin, Ohio, 43016, United States
Centricity Research (IACT Health) (Hampton Roads Center For Clinical Research, Inc.)) - Suffolk Multispecialty Research

Suffolk, Virginia, 23435, United States
Chandler Clinical Trials

Chandler, Arizona, 85224, United States
Charlottesville Medical Research

Charlottesville, Virginia, 22911, United States
Chattanooga Medical Research

Chattanooga, Tennessee, 37404, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Clinical Investigations of Texas (CIT)

Plano, Texas, 75075, United States
Clinical Neuroscience Solutions, INC.

Orlando, Florida, 32801, United States
Clinical Neuroscience Solutions, Inc

Memphis, Tennessee, 38119, United States
Clinical Neuroscience Solutions, Inc (Jacksonville)

Jacksonville, Florida, 32256, United States
Clinical Research of West Florida, Inc.

Tampa, Florida, 33606, United States
Clinical Trials Research

Lincoln, California, 95648, United States
Coastal Carolina Research Center

North Charleston, South Carolina, 29405, United States
Columbia University

New York, New York, 10032, United States
David Turbay, MD, PLLC (Elligo Health Research)

El Paso, Texas, 79905, United States
Del Sol Research Management, LLC

Tucson, Arizona, 85715, United States
Delta Waves, Inc.

Colorado Springs, Colorado, 80918, United States
Diabetes and Endocrinology Associates of Stark County, Inc.

Canton, Ohio, 44718, United States
Duke University Medical Center Heart Center Clinical Research Unit

Durham, North Carolina, 27710, United States
Eagle Clinical Research

Chicago, Illinois, 60621, United States
East Carolina University (ECU) Physicians - East Carolina Heart Institute - East Carolina University Location

Greenville, North Carolina, 27834, United States
Eastern Virginia Medical School

Norfolk, Virginia, 23510, United States
Elligo Health Research

Austin, Texas, 78704, United States
Fellows Research Alliance, Inc

Savannah, Georgia, 31406, United States
Fiel Family & Sports Medicine

Tempe, Arizona, 85383, United States
Franciscan Physician Network-Indiana Heart Physicians

Indianapolis, Indiana, 46237, United States
GenHarp Clinical Solutions

Evergreen Park, Illinois, 60805, United States
Georgia Clinical Research, LLC

Lawrenceville, Georgia, 30044, United States
Gulf Coast Clinical Research

Houston, Texas, 77070, United States
Henderson Clinical Trials

Henderson, Nevada, 89052, United States
Houston Methodist Research Institute

Houston, Texas, 77030, United States
Indago Research & Health Center, Inc.

Hialeah, Florida, 33012, United States
Indiana Clinical Research

Merrillville, Indiana, 46410, United States
Intrepid Research

Cincinnati, Ohio, 45245, United States
Iredell Memorial Hospital, Inc (Elligo Health Research)

Statesville, North Carolina, 28677, United States
Juno Research LLC

Houston, Texas, 77040, United States
Las Vegas Clinical Trials

Las Vegas, Nevada, 89030, United States
Lifedoc Research

Memphis, Tennessee, 38115, United States
Lillestol Research LLC

Fargo, North Dakota, 58104, United States
Lucas Research, Inc.

New Bern, North Carolina, 28557, United States
Marian David, MD, PC (Elligo Health Research)

New York, New York, 11415, United States
Marvel Clinical Research

Huntington Beach, California, 92647, United States
Medical Colleagues of Texas, LLP (Elligo Health Research)

Katy, Texas, 77450, United States
Medical Colleagues of Texas, LLP (Elligo Health Research)

Paris, Texas, 75462, United States
Nephrology Associates, PC - Downtown Augusta

Augusta, Georgia, 30901, United States
Noble Clinical Research

Tucson, Arizona, 85704, United States
Northridge Clinical Trials

Northridge, California, 91325, United States
Nuovida Research Center Corp

Miami, Florida, 33186, United States
Oasis Clinical Trials

Las Vegas, Nevada, 89121, United States
PRX Research - Mesquite

Mesquite, Texas, 75149, United States
Patron Medical - Andres Patron D.O. (Patron Ventures, LLC)

Pembroke, Florida, 33026, United States
Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States
Progressive Medical Research

Port Orange, Florida, 32127, United States
Punzi Medical Center

Carrollton, Texas, 75006, United States
Quality Clinical Research Inc. (QCR) - Omaha

Omaha, Nebraska, 68114, United States
Randomize Now

Peachtree City, Georgia, 30269, United States
Renown Regional Medical Center

Reno, Nevada, 89502, United States
Research Innovations (Elligo Health Research)

Beavercreek, Ohio, 45431, United States
Reserka, LLC

Miami, Florida, 33176, United States
STAT Research

Springboro, Ohio, 45066, United States
Saint Louis University

St Louis, Missouri, 63104, United States
San Antonio Clinical Trials

San Antonio, Texas, 78240, United States
San Jose Clinical Trials

San Jose, California, 95117, United States
Scottsdale Clinical Trials (Elite Clinical Network)

Scottsdale, Arizona, 85260, United States
Seacoast Kidney & Hypertension Specialist

Portsmouth, New Hampshire, 03801, United States
Southern Illinois School of Medicine

Springfield, Illinois, 62702, United States
Sugar Lakes Family Practice (Elligo Health Research)

Sugar Land, Texas, 77479, United States
Sun Research Institute (SRI) - San Antonio

San Antonio, Texas, 78215, United States
Synergy Groups Medical - Bissonet Site

Katy, Texas, 77494, United States
The Medical Research Group Inc.

Fresno, California, 93720, United States
The Pierone Research Institute (Elligo Health Research)

Vero Beach, Florida, 32960, United States
The Research Group of Lexington, LLC

Lexington, Kentucky, 40503, United States
The University of Chicago Medicine

Chicago, Illinois, 60637, United States
The University of Utah

Salt Lake City, Utah, 84108, United States
Triad Internal Medicine

Asheboro, North Carolina, 27205, United States
Triwest Research Associates

San Diego, California, 92108, United States
University of Alabama at Birmingham (UAB) - Vascular Biology and Hypertension Program

Birmingham, Alabama, 35294, United States
University of Buffalo

Buffalo, New York, 14215, United States
University of California Irvine Medical Center

Orange, California, 92868, United States
University of California San Diego (UCSD) - Altman Clinical and Translational Research Institute (ACTRI)

La Jolla, California, 92037, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Vanderbilt University Medical Center (VUMC)

Nashville, Tennessee, 37232, United States
Versailles Family Medicine

Versailles, Kentucky, 40383, United States
WR- Notus Clinical Trials, LLC

Charleston, South Carolina, 29414, United States
Williamette Valley Clincial Studies

Eugene, Oregon, 97404, United States

Conditions

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HYPERTENSION