Breakthrough trial aims to stop dangerous bleeding in emergency surgery

NCT ID NCT07288489

Summary

This study is testing whether a new drug called VMX-C001 can safely and effectively control bleeding during urgent, high-risk surgeries for patients taking common blood thinners (FXa DOACs). Researchers will compare the new drug to the usual standard of care in 800 participants. The main goal is to see if VMX-C001 leads to better or excellent bleeding control during the procedure, as judged by independent experts.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alfred Health, Melbourne

    Melbourne, Victoria, 3004, Australia

  • Aotearoa Clinical Trials - Middlemore (ACTT) Middlemore Hospital

    Papatoetoe, Auckland, 2025, New Zealand

  • Auckland City Hospital

    Grafton, Auckand, 1023, New Zealand

  • Beaumont Hospital, Royal Oak

    Royal Oak, Michigan, 48073, United States

  • Chandler Regional Medical Center (CRMC)

    Chandler, Arizona, 85224, United States

  • Christiana Care

    Newark, Delaware, 19718, United States

  • Denver Metro Orthopedics, P.C. - Englewood Location

    Englewood, Colorado, 80113, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Fiona Stanley Hospital

    Murdoch, Western Australia, 6150, Australia

  • Gold Coast University Hospital

    Southport, Queensland, 4215, Australia

  • HonorHealth John C Lincoln Medical Center

    Phoenix, Arizona, 85020, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mater Private Hospital

    South Brisbane, Queensland, 4101, Australia

  • Medical Center of the Rockies

    Fort Collins, Colorado, 80523, United States

  • Royal Brisbane and Women's Hospital (RBWH)

    Herston, Queensland, 4006, Australia

  • St Vincent Hospital, Melbourne

    Fitzroy, Victoria, 3065, Australia

  • St. Joseph's Hospital and Medical Center

    Phoenix, Arizona, 85013, United States

  • Stanford Hospital and Clinics

    Stanford, California, 94305, United States

  • Texas Tech University Health Sciences Center - El Paso

    El Paso, Texas, 79905, United States

  • The University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73126, United States

  • The University of Texas McGovern Medical School at Houston

    Houston, Texas, 77030, United States

  • University of Iowa Health Care

    Iowa City, Iowa, 52242, United States

  • University of South Florida

    Tampa, Florida, 33606, United States

  • Waikato Hospital

    Hamilton, Waikato Region, 3204, New Zealand

  • Wellington Hospital

    Newtown, Wellington Region, 6021, New Zealand

  • William Beaumont Hospital - Troy Campus

    Troy, Michigan, 48085, United States

Conditions

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