Antibody breakthrough could save artificial joints from infection
NCT ID NCT06621251
Summary
This study is testing whether a new antibody drug called TRL1068 can help treat chronic infections in artificial hip or knee joints. The goal is to clear the infection while keeping the original artificial joint in place, avoiding the need for a major two-stage replacement surgery. About 60 adults with confirmed joint infections will receive either the new antibody treatment plus a cleaning procedure and antibiotics, or will be observed while receiving the standard two-stage surgery.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Gulfcoast Research Institute
NOT_YET_RECRUITINGSarasota, Florida, 34232, United States
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Houston Methodist
RECRUITINGHouston, Texas, 77030, United States
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M3 Wake Research Associates
RECRUITINGWilmington, North Carolina, 28412, United States
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Mayo Clinic Jacksonville
RECRUITINGJacksonville, Florida, 32224, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10003, United States
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New England Baptist Hospital
RECRUITINGBoston, Massachusetts, 02120, United States
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North Texas Medical Research Institute
RECRUITINGRockwall, Texas, 75087, United States
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OrthoArizona
RECRUITINGGilbert, Arizona, 85234, United States
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Paradigm Research Center
RECRUITINGHouston, Texas, 77030, United States
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Phoenix Clinical Research
RECRUITINGTamarac, Florida, 33321, United States
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Proactive RGV
NOT_YET_RECRUITINGBrownsville, Texas, 78520, United States
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Sinai Hospital Baltimore
RECRUITINGBaltimore, Maryland, 21215, United States
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UCLA
RECRUITINGLos Angeles, California, 90024, United States
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University of Arkansas for Medical Sciences (UAMS)
RECRUITINGLittle Rock, Arkansas, 72205, United States
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University of Rochester
RECRUITINGRochester, New York, 14623, United States
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University of Texas Medical Branch at Galveston
RECRUITINGGalveston, Texas, 77555, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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Conditions
Explore the condition pages connected to this study.