New antibiotic combo shows promise for tough UTIs

NCT ID NCT05887908

Completed Disease control Sponsor: Meiji Seika Pharma Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tested two new antibiotic combinations (cefepime/nacubactam and aztreonam/nacubactam) against a standard treatment for complicated urinary tract infections and kidney infections in adults. About 614 participants took part to see if the new drugs work better or as well as the current therapy. The goal was to clear the infection and improve symptoms.

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Contacts and locations

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Locations

Meiji Research Site

Pleven, Bulgaria
Meiji Research Site

Rousse, Bulgaria
Meiji Research Site

Silistra, Bulgaria
Meiji Research Site

Sofia, Bulgaria
Meiji Research Site

Beijing, China
Meiji Research Site

Changchun, China
Meiji Research Site

Chongqing, China
Meiji Research Site

Fuyang, China
Meiji Research Site

Ganzhou, China
Meiji Research Site

Huaian, China
Meiji Research Site

Huzhou, China
Meiji Research Site

Nanchang, China
Meiji Research Site

Nanning, China
Meiji Research Site

Quanzhou, China
Meiji Research Site

Shanghai, China
Meiji Research Site

Shantou, China
Meiji Research Site

Shijiazhuang, China
Meiji Research Site

Taian, China
Meiji Research Site

Tianjin, China
Meiji Research Site

Xuancheng, China
Meiji Research Site

Yunnan, China
Meiji Research Site

Zhejiang, China
Meiji Research Site

Zhengzhou, China
Meiji Research Site

Hradec Králové, Czechia
Meiji Research Site

Liberec, Czechia
Meiji Research Site

Prague, Czechia
Meiji Research Site

Ústí nad Labem, Czechia
Meiji Research Site

Meegomäe, Võrumaa, Estonia
Meiji Research Site

Kohtla-Järve, Estonia
Meiji Research Site

Tallinn, Estonia
Meiji Research Site

Tartu, Estonia
Meiji Research Site

Kutaisi, Georgia
Meiji Research Site

Rustavi, Georgia
Meiji Research Site

Tbilisi, Georgia
Meiji Research Site

Fukuyama, Japan
Meiji Research Site

Gifu, Japan
Meiji Research Site

Ibaraki-Town, Higashiibaraki-County, Japan
Meiji Research Site

Iwakuni, Japan
Meiji Research Site

Kanazawa, Japan
Meiji Research Site

Kawachi-Nagano, Japan
Meiji Research Site

Kofu, Japan
Meiji Research Site

Kumamoto, Japan
Meiji Research Site

Matsumoto, Japan
Meiji Research Site

Mizumaki-Town, Onga-County, Japan
Meiji Research Site

Nagasaki, Japan
Meiji Research Site

Nankoku, Japan
Meiji Research Site

Ōita, Japan
Meiji Research Site

Ōtake, Japan
Meiji Research Site

Sagamihara, Japan
Meiji Research Site

Sapporo, Japan
Meiji Research Site

Shinjuku-ku, Japan
Meiji Research Site

Toyota, Japan
Meiji Research Site

Ueda, Japan
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Yokohama, Japan
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Riga, Latvia
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Valmiera, Latvia
Meiji Research Site

Kaunas, Lithuania
Meiji Research Site

Vilnius, Lithuania
Meiji Research Site

Galanta, Slovakia
Meiji Research Site

Rimavská Sobota, Slovakia
Meiji Research Site

Svidník, Slovakia

Conditions

Explore the condition pages connected to this study.

ACUTE PYELONEPHRITIS AP COMPLICATED URINARY TRACT INFECTION CUTI