New hope for leukemia patients who have run out of options

NCT ID NCT06366789

Summary

This is a first-in-human study to test a new drug, ZE46-0134, for adults with a hard-to-treat blood cancer called acute myeloid leukemia (AML). The cancer has come back or resisted standard treatment and has specific genetic changes (FLT3 or spliceosome mutations). The main goals are to find a safe dose, see how the body processes the drug, and get an early look at whether it might help control the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China Medical University Hospital

    NOT_YET_RECRUITING

    Taichung, 404327, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Eastern Health - Box Hill Hospital

    RECRUITING

    Melbourne, Victoria, 3128, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

  • Gachon University Gil Medical Center

    NOT_YET_RECRUITING

    Incheon, Gyeonggi-do, 21565, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Korea University Anam Hospital

    NOT_YET_RECRUITING

    Seoul, 02841, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Linear Clinical Research Ltd

    RECRUITING

    Perth, Western Australia, 6009, Australia

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • National Cheng Kung University Hospital

    NOT_YET_RECRUITING

    Tainan, 704302, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact

  • Seoul National University Hospital

    NOT_YET_RECRUITING

    Seoul, 03080, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taichung Veterans General Hospital

    NOT_YET_RECRUITING

    Xitun, 407219, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare

    NOT_YET_RECRUITING

    New Taipei City, 235041, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Alfred Hospital

    RECRUITING

    Melbourne, Victoria, 3004, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Catholic University of Korea Seoul St. Mary's Hospital

    NOT_YET_RECRUITING

    Seoul, 06591, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

  • The University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact

  • The University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact

  • University of Kansas

    RECRUITING

    Lawrence, Kansas, 66160, United States

    Contact

  • University of Maryland

    RECRUITING

    College Park, Maryland, 20742, United States

    Contact

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact

Conditions

Explore the condition pages connected to this study.