New hope for Tough-to-Treat leukemia: experimental drug added to standard chemo

NCT ID NCT03330821

Summary

This study is testing a new drug called pevonedistat, given alongside standard chemotherapy drugs, for adults newly diagnosed with high-risk acute myeloid leukemia (AML). The main goals are to find the safest and most effective dose of the new combination and to see if it helps more patients achieve remission. It is for patients who are considered fit for intensive chemotherapy.

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Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Los Angeles County-USC Medical Center

    Los Angeles, California, 90033, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Arizona Cancer Center - North Campus

    Tucson, Arizona, 85724, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.