Hope for young leukemia patients: new drug combo enters first human safety trial
NCT ID NCT06177067
First seen Nov 03, 2025 · Last updated Apr 22, 2026 · Updated 23 times
Summary
This early-stage study aims to find a safe dose of a new three-drug combination for children and young adults whose acute myeloid leukemia (AML) has returned or not responded to prior treatment. Researchers are testing a new drug called revumenib together with two standard chemotherapy drugs, azacitidine and venetoclax. The main goal is to see how well patients tolerate this combination and to find the safest dose for future studies.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Healthcare of Atlanta
RECRUITINGAtlanta, Georgia, 30329, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's Hospital Colorado
RECRUITINGAurora, Colorado, 80045, United States
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Children's Mercy Hospital of Kansas City
RECRUITINGKansas City, Missouri, 64108, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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Cook Children's Medical Center
RECRUITINGFort Worth, Texas, 76104, United States
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Memorial Sloan- Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Rady Children's Hospital
RECRUITINGSan Diego, California, 92132, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
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UT Southwestern/Simmons Cancer Center
RECRUITINGDallas, Texas, 75390, United States
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Conditions
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