New hope drug targets Tough-to-Treat advanced cancers

NCT ID NCT05384626

Recruiting now Disease control Sponsor: Nuvalent Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing a new oral medication called NVL-655 for people with advanced cancers that have a specific genetic change called ALK. The trial aims to find the safest and most effective dose and see how well the drug shrinks tumors. It's for adults with advanced lung cancer and other solid tumors who have tried other treatments or have limited options.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Azienda Ospedaliera Universitaria Ospedali Riuniti Umberto
RECRUITING

Ancona, 60126, Italy

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BC Cancer Center
RECRUITING

Vancouver, British Columbia, VZ 4E6, Canada

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Cancer Institute Hospital of JFCR
RECRUITING

Tokyo, 1358550, Japan

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Centre Leon Berard
RECRUITING

Lyon, 69373, France

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Chu De Nantes
RECRUITING

Nantes, 44093, France

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Chung-Shan Medical University Hospital
RECRUITING

Taichung, 402306, Taiwan

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Complejo Hospitalario Universitario de A Coruna
RECRUITING

A Coruña, 15006, Spain

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Cross Cancer Institute
RECRUITING

Edmonton, Alberta, T6G 1Z2, Canada

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Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States

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Duke University Medical Center
RECRUITING

Durham, North Carolina, 27705, United States

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Edinburgh Cancer Centre
RECRUITING

Edinburgh, EH4 2XU, United Kingdom

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Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITING

Milan, 20133, Italy

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Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States

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Georgetown University Medical Center
RECRUITING

Washington D.C., District of Columbia, 20007, United States

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Henry Ford Cancer Institute
RECRUITING

Detroit, Michigan, 48202, United States

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Hospital General Universitario Gregorio Maranon
RECRUITING

Madrid, 28009, Spain

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Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain

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IRCCS Istituto Tumori "G. Paolo II"
RECRUITING

Bari, 70124, Italy

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Institut Claudius Regaud
RECRUITING

Toulouse, 31059, France

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Institute Gustave Roussy
RECRUITING

Villejuif, 94805, France

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Instituto Europeo di Oncologia
RECRUITING

Milan, 20141, Italy

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Instituto Oncologico Veneto
RECRUITING

Padua, 35128, Italy

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Istituto Oncologico Svizzera Italiana
RECRUITING

Bellinzona, 6500, Switzerland

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John Hopkins University
RECRUITING

Baltimore, Maryland, 21224, United States

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Kanagawa Cancer Center
RECRUITING

Kanagawa, 2418515, Japan

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Kindai University Hospital
RECRUITING

Osaka, 5898511, Japan

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Laura & Isaac Perlmutter Cancer Center at NYU Langone Health
RECRUITING

New York, New York, 10016, United States

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LungenClinic Grosshansdorf GmbH
RECRUITING

Großhansdorf, 22927, Germany

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Luzerner Kantonsspital
RECRUITING

Lucerne, 6000, Switzerland

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MD Anderson Cancer Center
ACTIVE_NOT_RECRUITING

Houston, Texas, 77030, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

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Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States

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National Cancer Center
RECRUITING

Goyang-si, Gyeonggi-do, 10408, South Korea

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National Cancer Center Hospital
RECRUITING

Tokyo, 1040051, Japan

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National Cancer Centre Singapore
RECRUITING

Singapore, Singapore, 168583, Singapore

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National Cheng Kung University Hospital
RECRUITING

Tainan, 70403, Taiwan

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National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan

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National University Hospital
RECRUITING

Singapore, Singapore, 119074, Singapore

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OSU Brain & Spine Hospital
RECRUITING

Columbus, Ohio, 43210, United States

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Okayama University Hospital
RECRUITING

Okayama, 7008558, Japan

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Ospedale Santa Maria delle Croci
RECRUITING

Ravenna, 48100, Italy

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Peter MacCallum Cancer Centre
RECRUITING

Melbourne, Victoria, 3000, Australia

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Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, 4102, Australia

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Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 0A3, Canada

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Regina Elena Institute for Cancer Research
RECRUITING

Rome, 00144, Italy

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Royal Marsden Hospital
RECRUITING

Sutton, Surrey, SM2 5PT, United Kingdom

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Royal North Shore Hospital
RECRUITING

Sydney, New South Wales, 2065, Australia

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Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea

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Sarah Cannon
RECRUITING

Nashville, Tennessee, 37203, United States

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Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea

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Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea

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Shizuoka Cancer Center
RECRUITING

Shizuoka, 4118777, Japan

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Stanford Cancer Institute
RECRUITING

Stanford, California, 94305, United States

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The Christie NHS Foundation Trust
RECRUITING

Manchester, M20 4BX, United Kingdom

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The Netherlands Cancer Institute
RECRUITING

Amsterdam, 1066 CX, Netherlands

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The Ottawa Hospital Cancer Center
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada

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The Royal Marsden - Chelsea
RECRUITING

London, SM2 5PT, United Kingdom

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UOMI Cancer Center
RECRUITING

Barcelona, 08017, Spain

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Universitair Ziekenhuis Antwerpen (UZA)
RECRUITING

Antwerp, 2650, Belgium

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Universitaire Ziekenhuizen Leuven Campus Gastthuisberg
RECRUITING

Leuven, 3000, Belgium

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Universitatsklinikum Koln - University Hospital Cologne
RECRUITING

Cologne, 50937, Germany

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University Medical Center Groningen (UMCG)
RECRUITING

Groningen, 9713 GZ, Netherlands

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University of California Irvine Medical Center
RECRUITING

Orange, California, 92868, United States

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University of California, Davis Comprehensive Cancer Center
RECRUITING

Sacramento, California, 95817, United States

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University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States

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University of Colorado Cancer Center
RECRUITING

Aurora, Colorado, 80045, United States

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University of Miami; Sylvester Cancer Center
RECRUITING

Miami, Florida, 33136, United States

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University of Pennsylvania, Abramson Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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Universitätsklinikum Frankfurt
RECRUITING

Frankfurt, 60590, Germany

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Universkitatsklinikum Heidelberg - University Hospital Heidelberg
RECRUITING

Heidelberg, 69126, Germany

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Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain

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Wakayama Medical University Hospital
RECRUITING

Wakayama, 6418510, Japan

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Washington University School of Medicine Siteman Cancer Center
RECRUITING

St Louis, Missouri, 63310, United States

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Winship Cancer Institute, Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

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Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED SOLID TUMOR METASTATIC SOLID TUMOR