First human tests begin for new genetic disease therapy
NCT ID NCT06405633
Summary
This early-stage study is testing a new drug called WVE-006 for people with Alpha-1 Antitrypsin Deficiency (AATD), a genetic condition that can damage the lungs and liver. Researchers will give the drug to 24 participants to first check if it's safe and how the body handles it. The main goal is to see if the treatment increases a key protective protein that people with AATD lack.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cambridge University - Addenbrooke's Hospital
RECRUITINGCambridge, CB2 0QQ, United Kingdom
Contact Email: •••••@•••••
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Dalhousie University - Queen Elizabeth II Health Sciences Centre
RECRUITINGHalifax, Nova Scotia, B3H 1V7, Canada
Contact Email: •••••@•••••
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Inspiration Research Limited
RECRUITINGToronto, Ontario, M5T 3A9, Canada
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Queen Elizabeth Hospital, University Hospital Birmingham
RECRUITINGBirmingham, B15 2GW, United Kingdom
Contact Email: •••••@•••••
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Royal Free London NHS Foundation Trust
RECRUITINGLondon, SW8 3RN, United Kingdom
Contact Email: •••••@•••••
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St. Vincent's Hospital, Melbourne
RECRUITINGFitzroy, Victoria, 3065, Australia
Contact Email: •••••@•••••
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Turku University Hospital
RECRUITINGTurku, 20520, Finland
Contact Email: •••••@•••••
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Universitaetsklinikum Aachen, AoeR
RECRUITINGAachen, 52074, Germany
Contact Email: •••••@•••••
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Waikato Hospital
RECRUITINGHamilton, 3204, New Zealand
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.