New drug combo aims to halt debilitating nerve damage

NCT ID NCT05065554

Summary

This study is testing whether combining the drug acalabrutinib with an antibody treatment (like rituximab) is safe and effective for people with nerve damage (neuropathy) caused by specific blood conditions. The goal is to control the underlying disease and improve or stabilize nerve symptoms like weakness, numbness, and walking problems. About 33 participants will receive the treatment for up to four years and be followed for two more.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02214, United States

Conditions

Explore the condition pages connected to this study.