Zapping the brain to steady Parkinson's steps?

NCT ID NCT07767006

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether combining two non-invasive brain stimulation techniques—transcranial direct current stimulation (tDCS) and transcranial ultrasound stimulation (TUS)—can improve balance and posture in people with Parkinson's disease. Participants are randomly assigned to one of four treatment schedules, ranging from daily sessions over two weeks to a shorter one-week course, or a sham (placebo) version. The goal is to see which schedule, if any, reduces motor symptoms like tremor, stiffness, and postural instability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Combined transcranial direct current stimulation (tDCS) and transcranial ultrasound stimulation (TUS)
What this could lead to
If effective, this could point toward a non-invasive way to improve balance and reduce falls in people with Parkinson's disease.
What could go wrong
This is an early-stage trial, and the optimal schedule is unknown. Results may vary, and the effects might not last or translate to real-world improvements.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Spaulding Rehabilitation Hospital for Continuing Care

    Cambridge, Massachusetts, 02138, United States