Could a patch replace opioids after knee surgery?
NCT ID NCT07439666
First seen Feb 28, 2026 · Last updated May 23, 2026 · Updated 10 times
Summary
This study tests whether a device called NEUROCUPLE can lower pain and the need for opioid painkillers after total knee replacement. About 274 adults having knee surgery will use either the active device or an identical-looking placebo patch for 7 days after their operation. Researchers will track pain scores and opioid use during the first 24 hours and up to 7 days after surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UPMC East Hospital
Pittsburgh, Pennsylvania, 15146, United States
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UPMC Passavant Hospital
Pittsburgh, Pennsylvania, 15237, United States
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UPMC Shadyside Hospital
Pittsburgh, Pennsylvania, 15232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Conditions
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