Experimental injection tested for devastating skin disease
NCT ID NCT05856526
Summary
This study tested whether a medicine called spesolimab could help people with Netherton syndrome, a rare and severe genetic skin disorder. Participants aged 12 and older received either spesolimab or a placebo injection for 4 months, after which everyone could receive the active drug. The main goal was to see if the treatment significantly reduced skin redness and scaling. The trial was terminated early, and the final results are not yet publicly available.
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Contacts and locations
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Locations
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ASMC-IPSMC-skin and Veneral Diseases
Sofia, 1407, Bulgaria
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Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino
Torino, 10126, Italy
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Beijing Children's Hospital, Capital Medical University
Beijing, 100045, China
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Dermatology Hospital, Chinese Academy of Medical Sciences
Nanjing, 210000, China
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Erasmus MC Sophia Kinderziekenhuis
Rotterdam, 3015 GD, Netherlands
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HOP Saint-Louis
Paris, 75010, France
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Hospital Tunku Azizah
Kuala Lumpur, 50300, Malaysia
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Istituto Dermopatico Dell'Immacolata - IDI - IRCCS
Roma, 00167, Italy
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Juntendo University Urayasu Hospital
Chiba, Urayasu, 279-0021, Japan
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Klinikum der Universität München AÖR
München, 80337, Germany
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Mission Dermatology Center
Rancho Santa Margarita, California, 92688, United States
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Nagoya University Hospital
Aichi, Nagoya, 466-8560, Japan
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Okayama University Hospital
Okayama, Okayama, 700-8558, Japan
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Queen Elizabeth University Hospital
Glasgow, G51 4TF, United Kingdom
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Shanghai Skin Disease Hospital
Shanghai, 200000, China
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Sourasky Medical Center
Tel Aviv, 6423906, Israel
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Southern Medical University Dermatology Hospital
Guangzhou, 510091, China
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The Children's Hospital Zhejiang University School Of Medicine
Hangzhou, 310000, China
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The First Affiliated Hospital, Zhejiang University
Hangzhou, 310003, China
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ULS de São José, E.P.E. - Hospital Sto. António Capuchos
Lisbon, 1169-050, Portugal
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University Children Hospital Zürich
Zurich, 8032, Switzerland
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Universitätsklinikum Heidelberg
Heidelberg, 69120, Germany
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Universitätsklinikum Schleswig-Holstein, Campus Kiel
Kiel, 24105, Germany
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Virginia Clinical Research, Inc.
Norfolk, Virginia, 23502, United States
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Westmead Hospital
Westmead, New South Wales, 2145, Australia
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Xinhua Hospital Affiliated to Shanghai Jiaotong University
Shanghai, 200092, China
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Yale University School of Medicine
New Haven, Connecticut, 06519, United States
Conditions
Explore the condition pages connected to this study.