New hope for Hard-to-Treat cancers: drug combo enters human testing

NCT ID NCT05661201

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 20 times

Summary

This early-phase study tests the safety of combining two drugs, NEROFE and doxorubicin, in people with advanced solid tumors that have a KRAS mutation and express ST2. The main goal is to find the best dose and schedule. About 24 participants will receive weekly infusions of both drugs.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Georgetown Lombardi Comprehensive Cancer Center

    RECRUITING

    Washington D.C., District of Columbia, 20007, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.