New hope for heartburn sufferers: study tests combo therapy for NERD
NCT ID NCT07174882
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is testing a new combination treatment for non-erosive reflux disease (NERD), a common form of GERD that causes heartburn and other symptoms. The treatment adds therapies to strengthen the esophagus's natural barrier on top of standard acid-reducing medication. Researchers will track symptom changes and measure improvements in the esophageal lining in 60 adults over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
complex therapy (acid-suppressive medication plus treatments to strengthen esophageal lining)
What this could lead to
If successful, this could point toward a more effective treatment for NERD, especially for patients who don't get relief from standard acid-blocking drugs.
What could go wrong
This is a small, early-stage study with only 60 participants, so results may not apply to everyone. The complex therapy may not prove better than standard care, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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V.Kh.Vasilenko Clinic of Propedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M.Sechenov First Moscow State Medical University (Sechenov University). Gastroenterology department, outpatient clinic.
Moscow, 119991, Russia